Multidisciplinary approach of colorectal cancer liver metastases

查看全文 作　　者：Giammaria [1]Fiorentini;Donatella [1]Sarti;Camillo [2]Aliberti;Riccardo [2]Carandina;Andrea [3]Mambrini;Stefano [4]Guadagni

机构地区：[1]Onco-Ematology Department,Azienda Ospedaliera 'Ospedali Riuniti Marche Nord';[2]Oncology Radiodiagnostics Department,Oncology Institute of Veneto,Institute for the Research and Treatment of Cancer;[3]Oncology Department,Carrara General Hospital;[4]Department of Applied Clinical Sciences and Biotechnology,Section of General Surgery,University of L’Aquila

出　　处：《World Journal of Clinical Oncology》索引2017年第8卷第3期,共13页

摘　　要：Large bowel cancer is a worldwide public health challenge.More than one third of patients present an advanced stage of disease at diagnosis and the liver is the most common site of metastases.Selection criteria for early diagnosis,chemotherapy and surgery have been recently expanded.The definition of resectability remains unclear.The presence of metastases is the most significant prognostic factor.For this reason the surgical resection of hepatic metastases is the leading treatment.The most appropriate resection approach remains to be defined.The two step and simultaneous resection processes of both primary and metastases have comparable survival long-term outcomes.The advent of targeted biological chemotherapeutic agents and the development of loco-regional therapies(chemoembolization,thermal ablation,arterial infusion chemotherapy) contribute to extend favorable results.Standardized evidence-based protocols are missing,hence optimal management of hepatic metastases should be single patient tailored and decided by a multidisciplinary team.This article reviews the outcomes of resection,systemic and loco-regional therapies of liver metastases originating from large bowel cancer. 关键词：COLORECTAL CANCER Chemoembolization LIVER METASTASES Hepatic resection COLORECTAL CANCER LIVER METASTASES CHEMOTHERAPY Arterial infusion CHEMOTHERAPY RADIOEMBOLIZATION

相关文献

参考文献（113）
引证文献（5）
耦合文献（30）

参考文献(113)

引证文献(5)

耦合文献(30)

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

Multidisciplinary approach of colorectal cancer liver metastases

参考文献(113)

引证文献(5)

耦合文献(30)

用户提示