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Post-appendectomy pelvic abscess with extended-spectrum beta-lactamase producing Escherichia coli : A case report and review of literature

查看全文 作　　者：Andrew [1,2]Tse;Rajkumar [3]Cheluvappa;Selwyn [1,2]Selvendran 高影响力作者 机构地区：[1]Department of Surgery, St George Public Hospital;[2]St George and Sutherland Clinical School, University of New South Wales;[3]BN Program, Discipline of Nursing and Midwifery, University of Canberra高影响力机构 出　　处：《World Journal of Clinical Cases》索引2018年第6卷第16期,共7页高影响力期刊 摘　　要：BACKGROUND Appendicitis, the inflammation of the appendix, is the most common abdominal surgical emergency requiring expedient surgical intervention. Extendedspectrum beta-lactamases(ESBLs) are bacterial enzymes that catalyse the degradation of the betalactam ring of penicillins and cephalosporins(but without carbapenemase activity), leading to resistance of these bacteria to beta-lactam antibiotics. Recent increases in incidence of ESBL-producing bacteria have caused alarm worldwide. Proportion estimates of ESBLEnterobacteriaceae hover around 46% in China, 42% in East Africa, 12% in Germany, and 8% in the United States.CASE SUMMARY The impact of ESBL-producing bacteria on appendiceal abscesses and consequent pelvic abscesses are yet to be examined in depth. A literature review using the search words 'appendiceal abscesses' and 'ESBL Escherichia coli(E. coli)' revealed very few cases involving ESBL E. coli in any capacity in the context of appendiceal abscesses. This report describes the clinical aspects of a patient with appendicitis whodeveloped a postoperative pelvic abscess infected with ESBL-producing E. coli. In this report, we discuss the risk factors for contracting ESBL E. coli infection in appendicitis and post-appendectomy pelvis abscesses. We also discuss our management approach for postappendectomy ESBL E. coli pelvic abscesses, including drainage, pathogen identification, and pathogen characterisation. When ESBL E. coli is confirmed, carbapenem antibiotics should be promptly administered, as was done efficaciously with this patient. Our report is the first one in a developed country involving ESBL E. coli related surgical complications in association with a routine laparoscopic appendectomy.CONCLUSION Our report is the first involving ESBL E. coli and appendiceal abscesses, and that too consequent to laparoscopic appendectomy. 关 键 词：APPENDECTOMY APPENDICEAL ABSCESS Appendicitis BETA-LACTAM Antibiotic resistance BETA-LACTAMASE Carbanepem CEPHALOSPORIN Escherichia coli Extended-spectrum BETA-LACTAMASE Infection Pelvic ABSCESS Penicillin Case report
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