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Acquisition of deleterious mutations duringpotato polyploidization

查看全文 作  者:Qun [1,2]Lian;Die [1]Tang;Zhiyan [1]Bai;Jianjian [2]Qi;Fei [3,4]Lu;Sanwen [1]Huang;Chunzhi [1]Zhang 高影响力作者 机构地区:[1]Genome Analysis Laboratory of the Ministry of Agriculture,Agricultural Genomics Institute,theChinese Academy of Agricultural Sciences;[2]Inner Mongolia Potato Engineering and Technology Research Centre,Inner Mongolia University;[3]The State Key Laboratory of Plant Cell and Chromosome Engineering,Institute of Genetics and Developmental Biology,the Chinese Academy of Sciences;[4]CAS-JIC Centre of Excellence for Plant and Microbial Science(CEPAMS),Shanghai Institutes for Biological Sciences,the Chinese Academy of Sciences高影响力机构 出  处:《Journal of Integrative Plant Biology》索引2019年第61卷第1期,共5页高影响力期刊 基  金:the National Natural Science Foundation of China (31601360 to C.Z.);the Chinese Academy of Agricultural Sciences (ASTIP-CAAS to S.H.);the Ministry of Agriculture and Rural Affairs of the People’s Republic of China;the Shenzhen municipal;Dapeng district governments 摘  要:Potatoes(Solanum tuberosum L.) represent an important tuber crop, worldwide. During its prolonged clonal propagation, numerous deleterious mutations have accumulated in the potato genome,leading to severe inbreeding depression; however,the shaping of this mutation burden during polyploidization and improvement is largely unknown.Here, we sequenced 20 diploid landraces of the Stenotomum group, eight tetraploid landraces, and 20 tetraploid modern cultivars, to analyze variations in their deleterious mutations. We show that deleterious mutations accumulated rapidly during the polyploidization of tetraploid potatoes. This study provides a foundation for future potato improvement. 关 键 词:POTATOES STUDY
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