The impact of genomic relatedness between populations on the genomic estimated breeding values

查看全文 作　　者：Peipei [1,2]Ma;Ju [1]Huang;Weijia [3]Gong;Xiujin [1]Li;Hongding [4]Gao;Qin [1]Zhang;Xiangdong [1]Ding;Chonglong [5]Wang

机构地区：[1]National Engineering Laboratory for Animal Breeding,Laboratory of Animal Genetics,Breeding and Reproduction,Ministry of Agriculture,College of Animal Science and Technology,China Agricultural University,Beijing 100193,China;[2]Department of Animal Science,School of Agriculture and Biology,Shanghai Jiao Tong University,Shanghai 200240,China;[3]Gènes DIFFSUION,3595 Route de Tourna,59500 Douai,France;[4]Center for Quantitative Genetics and Genomics,Department of Molecular Biology and Genetics,Aarhus University,Tjele,Denmark;[5]Key Laboratory of Pig Molecular Quantitative Genetics,Institute of Animal Husbandry and Veterinary Medicine,Anhui Academy of Agricultural Sciences,Hefei 230031,China

出　　处：《Journal of Animal Science and Biotechnology》索引2018年第9卷第4期,共6页

基　　金：supported by the earmarked fund for China Agriculture Research System(CARS-36);the National Natural Science Foundation of China(31671327,31701077,31371258);the Program for Changjiang Scholar and Innovation Research Team in University(Grant No.IRT1191);Anhui Science and Technology Key Project(17030701008);Anhui Academy of Agricultural Sciences Key Laboratory Project(18S0404) 摘　　要：In genomic selection, prediction accuracy is highly driven by the size of animals in the reference population(RP).Combining related populations from different countries and regions or using a related population with large size of RP has been considered to be viable strategies in cattle breeding. The genetic relationship between related populations is important for improving the genomic predictive ability. In this study, we used 122 French bulls as test individuals. The genomic estimated breeding values(GEBVs) evaluated using French RP, America RP and Chinese RP were compared.The results showed that the GEBVs were in higher concordance using French RP and American RP compared with using Chinese population. The persistence analysis, kinship analysis and the principal component analysis(PCA) were performed for 270 French bulls, 270 American bulls and 270 Chinese bulls to interpret the results. All the analyses illustrated that the genetic relationship between French bulls and American bulls was closer compared with Chinese bulls. Another reason could be the size of RP in China was smaller than the other two RPs. In conclusion, using RP of a related population to predict GEBVs of the animals in a target population is feasible when these two populations have a close genetic relationship and the related population is large. 关键词：GENOMIC PREDICTION GENOMIC relationship JOINT POPULATION PREDICTION

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The impact of genomic relatedness between populations on the genomic estimated breeding values

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