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The cardiovascular aspects of a Ménière’s disease population——A pilot study

查看全文 作　　者：Angela Reis [1]Rego;David [1]Dias;Ana [1]Pinto;SANDra Sousa e [1]Castro;Telma [1]Feliciano;Cecília Almeida e [1]Sousa 高影响力作者 机构地区：[1]ENT Department, Centro Hospitalar e Universitário do Porto, Largo do Prof.Abel Salazar高影响力机构 出　　处：《Journal of Otology》索引2019年第14卷第2期,共6页高影响力期刊 摘　　要：Introduction:MD is considered a rare disease.An adequate model that explains MD's pathophysiology is not well established.Recently,the vascular theory of the disease has been revived.Objectives:To characterize a MD population according to its cardiovascular risk and correlate it to the MD clinical course.Methods:In this retrospective chart study the data of 31 MD patients observed between January 2017 and April 2018 in a tertiary university hospital were reviewed.Patients included in the study were diagnosed according to the Barany Society criteria.Lost follow-ups,patients with autoimmune disease,atopy or allergy,major psychiatric disease and migraine were excluded.Age,gender,cardiovascular risk factors,audiometric and vestibular parameters,occurrence of MD attacks in the previous 6 months,vestibular medication in course and time course of MD were recorded and compared between groups(with and without cardiovascular risk factors).Results:31 patients(61.3%females)mean aged 60.3 years(±9.7)were studied.74%of the population had at least one risk factor and 51.6%of patients had attacks in the last 6 months.There was a statistically significant difference in the occurrence of MD attacks in the last 6 months(p=0.014)between MD patients with and without risk factors.Mean PTA thresholds were higher and speech discrimination was lower in individuals with more cardiovascular risk factors.Conclusions:Treatment of MD focusing on vascular risk factors may allow a better control of symptoms and result in a decreased need for ablative procedures in this disorder. 关 键 词：Meniere DISEASE CARDIOVASCULAR DISEASE HYPERTENSION PROGNOSIS
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