Effects of percutaneous varicocele repair on testicular volume:results from a 12-month follow-up

查看全文 作　　者：Andrea [1]Sansone;Danilo Alunni [2]Fegatelli;Carlotta [1]Pozza;Giorgio [1]Fattorini;Rosa [3]Lauretta;Marianna [1]Minnetti;Francesco [1]Romanelli;Pierleone [4]Lucatelli;Mario [4]Corona;Mario [4]Bezzi;Francesco [1]Lombardo;Andrea [1]Lenzi;Daniele [1]Gianfrilli

机构地区：[1]Departme nt of Experime ntal Medici ne, Sa pie nza Un iversity of Rome, Rome 00161, Italy;[2]Department of Public Health and In fectious Diseases, Sapienza University of Rome, Rome 00161, Italy;[3]Unit of Endocrinology, Regina Elena National Cancer Institute, Rome 00144, Italy;[4]Vascular and Interventional Radiology Unit, Department of Radiological, Oncological and Anatomo-Pathological Sciences, Sapienza-University of Rome, Rome 00161, Italy

出　　处：《Asian Journal of Andrology》索引2019年第21卷第4期,共5页

摘　　要：Varicocele is a comm on fin ding in men. Varicocele correcti on has bee n advocated for young patients with testicular hypotrophy, but there is a lack of morphofunctional follow-up data. We assessed whether percutaneous treatment of left varicocele is associated with testicular 'catch-up growth' in the following 12 months by retrospectively reviewing data from an electronic database of 10 656 patients followed up in our clinic between 2006 and 2016. We selected all young adults (<35 years) with left varicocele who un derwe nt percuta neous treatment, had a minimum of 12 mon ths' ultraso und imagi ng follow-up, and had no other con ditions affecting testicular volume. One hundred and fourteen men (mean±standard deviation [s.d.] of age: 22.8 ± 5.4 years) met the inclusion and exclusion criteria. Left testicular hypotrophy (LTH), defined as a >20% difference between left and right testicular volume at baseline, was observed in 26 (22.8%) men. Participants with LTH (mean±s.d.: 14.5 ± 2.7 ml) had lower baseline testicular volume compared to those without LTH (mean±s.d.: 15.7 ± 3.8 ml;P= 0.032). Repeated measures mixed models showed a sign ifica nt in teraction betwee n LTH and time posttreatme nt when correcting for baseli ne left testicular volume (β= 0.114, 95% confidence interval [Cl]: 0.018-0.210, P=0.020), resulting in a catch-up growth of up to 1.37 ml per year (95% Cl: 0.221- 2.516). Age at intervention was also associated with reduced testicular volume (-0.072 ml per year, 95% Cl:-0.135--0.009;P = 0.024). Percutaneous treatment of left varicocele in young adults with LTH can result in catch-up growth over 1 year of follow-up. The reproductive and psychological implicati ons of these findings n eed to be confirmed in Ion ger and larger prospective studies. 关键词：CATCH-UP growth PERCUTANEOUS treatment TESTICULAR hypotrophy TESTICULAR ultrasound TESTICULAR volume VARICOCELE young adults

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Effects of percutaneous varicocele repair on testicular volume:results from a 12-month follow-up

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