Photothermal performance of MFe2O4 nanoparticles

查看全文 作　　者：Kuang [1]Wang;Peng [1]Yang;Ranran [1]Guo;Xianxian [1]Yao;Wuli [1]Yang

机构地区：[1]State Key Laboratory of Molecular Engineering of Polymer and Department of Macromolecular Science, Fudan University

出　　处：《Chinese Chemical Letters》索引2019年第30卷第12期,共4页

基　　金：supported by the National Key R&D Program of China(No.2016YFC1100300);National Natural Science Foundation of China(Nos.51873041 and 51473037) 摘　　要：Photothermal therapy(PTT) has emerged as one of the promising cancer therapy approaches.As a representative photothermal agent(PTA),magnetite possesses many advantages such as biodegradability and biocompatibility.However,photothermal instability hampers its further application.Herein,we systematically synthesized three kinds of ferrite nanoparticles and detailedly investigated their photothermal effect.Compared with Fe304 and MnFe2 O4 nanoparticles,ZnFe2 O4 nanoparticles exhibited a superior photothermal effect.After preservation for 70 days,the photothermal effect of Fe304 and MnFe2 O4 nanoparticles observably declined while ZnFe2 O4 nanoparticles showed slight decrease.Furthermore,in vitro experiment,ZnFe2 O4 nanoparticles showed little toxicity to cells and achieved outstanding effect in killing cancer cells under NIR laser irradiation.Overall,through synthesizing and studying three kinds of ferrite MFe2 O4 nanoparticles,we obtained ferrites as PTAs and learned about their changing trend in photothermal effect,expecting it can inspire further exploration of photothermal agents. 关键词：Photothermal therapy Photothermal agent MFe2O4 OXIDIZATION STABLE

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Photothermal performance of MFe2O4 nanoparticles

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