Geoepidemiologic variation in outcomes of primary sclerosing cholangitis

查看全文 作　　者：Tej I [1]Mehta;Simcha [2]Weissman;Brian M [3]Fung;James H [4]Tabibian

机构地区：[1]Department of Medicine,University of South Dakota Sanford School of Medicine,Sioux Falls,SD 57108,United States;[2]Department of Medicine,Hackensack University-Palisades Medical Center,North Bergen,NJ 07047,United States;[3]Department of Medicine,Olive View-UCLA Medical Center,Sylmar,CA 91342,United States;[4]Department of Medicine,UCLA-Olive View Medical Center,Sylmar,CA 91342,and Health Sciences Clinical Associate Professor,David Geffen School of Medicine at UCLA,Los Angeles,CA 90095,United States

出　　处：《World Journal of Hepatology》索引2020年第12卷第4期,共9页

摘　　要：Primary sclerosing cholangitis(PSC)is a chronic,progressive,hepatobiliary disease characterized by inflammation and fibrosis of the intra-and extra-hepatic bile ducts.Its natural history is one that generally progresses towards cirrhosis,liver failure,cholangiocarcinoma,and ultimately disease-related death,with a median liver transplantation-free survival time of approximately 15-20 years.However,despite its lethal nature,PSC remains a heterogenous disease with significant variability in outcomes amongst different regions of the world.There are also many regions where the outcomes of PSC have not been studied,limiting the overall understanding of this disease worldwide.In this review,we present the geoepidemiologic variations in outcomes of PSC,with a focus on survival pre-and post-liver transplantation as well as the concurrence of inflammatory bowel disease and hepatobiliary neoplasia. 关键词：CHOLANGIOCARCINOMA Inflammatory BOWEL disease Liver transplantation GEOGRAPHY BILIARY TRACT AUTOIMMUNE

相关文献

参考文献（77）
引证文献（0）
耦合文献（25）

参考文献(77)

耦合文献(25)

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

Geoepidemiologic variation in outcomes of primary sclerosing cholangitis

参考文献(77)

耦合文献(25)

用户提示