Inflammatory myofibroblastic tumor of the liver:A case report and review of literature

查看全文 作　　者：Alexandra [1]Filips;Martin H [2]Maurer;Matteo [3]Montani;Guido [1]Beldi;Anja [1]Lachenmayer

机构地区：[1]Department of Visceral Surgery and Medicine,Inselspital,Bern University Hospital,University of Bern,Bern 3010,Switzerland;[2]Department of Radiology,Inselspital,Bern University Hospital,University of Bern,Bern 3010,Switzerland;[3]Institute of Pathology,Inselspital,University Hospital,University Bern,Bern 3010,Switzerland

出　　处：《World Journal of Hepatology》索引2020年第12卷第4期,共14页

摘　　要：BACKGROUND Inflammatory myofibroblastic tumors of the liver(IMTL)are extremely rare neoplasms and very little is known about their clinical presentation,pathogenesis,and biological behavior.Due to their absolute rarity,it is almost impossible to obtain a definite diagnosis without histological examination.Because of their intermediate biological behavior with the risk for local recurrence and metastases,surgical resection is recommend whenever IMTL is suspect.CASE SUMMARY We herein present a case of an otherwise healthy 32-year-old woman who presented with intermittent fever,unclear anemia,malaise and right flank pain 4 mo postpartum.The liver mass in segment IVa/b was highly FDG avid in the positron emission tomography-computed tomography.Hepatic resection was performed achieving a negative resection margin and an immediate resolution of all clinical symptoms.Histological analysis diagnosed the rare finding of an inflammatory myofibroblastic tumor of the liver and revealed cytoplasmic anaplastic lymphoma kinase expression by immunohistochemistry.Twelve months follow-up magnetic resonance imaging showed no recurrence and no metastases in the fully recovered patient.CONCLUSION IMTLs are extremely rare and difficult to diagnose.Due to their intermediate biological behavior,surgical resection should be perform whenever feasible and patients should be followed-up in order to detect recurrence and metastasis as early as possible. 关键词：INFLAMMATORY myofibroblastic TUMOR HEPATIC INFLAMMATORY ANAPLASTIC LYMPHOMA kinase-expression Case report Review

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Inflammatory myofibroblastic tumor of the liver:A case report and review of literature

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