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Effects and mechanisms of acupuncture and electroacupuncture for functional dyspepsia:A systematic review

查看全文 作  者:Yu [1,2]Guo;Wei [1]Wei;Jiande DZ [2,3]Chen 高影响力作者 机构地区:[1]Department of Gastroenterology,Wangjing Hospital of China Academy of Chinese Medical Sciences,Beijing 100102,China;[2]Division of Gastroenterology and Hepatology,Johns Hopkins University School of Medicine,Baltimore,MD 21224,United States;[3]Division of Gastroenterology and Hepatology,University of Michigan School of Medicine,Ann Arbor,MI 48109,United States高影响力机构 出  处:《World Journal of Gastroenterology》索引2020年第26卷第19期,共18页高影响力期刊 基  金:Supported by the National Natural Science Foundation of China,No.81703923 and No.81820108033. 摘  要:BACKGROUND Functional dyspepsia(FD)is a common digestive disease with limited therapeutic options.According to evidence-based clinical practice,acupuncture or electroacupuncture(EA)seems to be a promising therapy for patients with FD.However,there is still a lack of systematic reviews that have analyzed current clinical trials for a better understanding of mechanisms involved in the ameliorating effect of acupuncture and EA on FD.AIM To evaluate the results and qualities of existing clinical evidence for researching the underlying mechanisms of acupuncture/EA in treating FD.METHODS A systematic search of the literature was performed to identify randomized controlled trials in which research on the mechanism of acupuncture or EA was conducted in FD patients.Databases searched included PubMed,EMBASE,Cochrane Library,and Web of Science.Data extraction and quality assessment were completed by two investigators independently and the results of quality evaluation were exported through Review Manager V5.3.RESULTS Eight studies were included in this review with a total of 17 items for detecting techniques for mechanistic research.Positive effects of acupuncture and EA were observed in regulating gastric motility,gastric accommodation,mental status,gastrointestinal hormones,and central and autonomic functions while improving dyspeptic symptoms and quality of life.CONCLUSION The key findings of this systematic review support the potential of acupuncture and EA in altering the heterogeneous pathophysiology in patients with FD.However,high-quality studies with well-planned designs are necessary to provide more credible evidence. 关 键 词:ACUPUNCTURE ELECTROACUPUNCTURE Functional dyspepsia Gastrointestinal motility Systematic review
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