Interstitial lung disease and diabetes

查看全文 作　　者：Venkat [1]Rajasurya;Kulothungan [2]Gunasekaran;Salim [3]Surani

机构地区：[1]Department of Pulmonary and Critical Care,Novant Health System,Winston-Salem,NC 27103,United States;[2]Department of Pulmonary and Critical Care,Yale-New Haven Health Bridgeport Hospital,CT 06610,United States;[3]Department of Pulmonary Critical Care and Sleep Medicine,Texas A&M Health Science Center,Bryan,TX 77807,United States

出　　处：《World Journal of Diabetes》索引2020年第11卷第8期,共7页

摘　　要：Diabetes mellitus (DM) is a chronic metabolic disease and its prevalence has beensteadily increasing all over the world. DM and its associated micro andmacrovascular complications result in significant morbidity and mortality. Themicrovascular complications are usually manifested as retinopathy, neuropathy,nephropathy and macrovascular complications generally affect the cardiovascularsystem. In addition to these complications, DM also affects the lungs because of itsrich vascularity and abundance in connective tissue (collagen and elastin). DMhas been found to cause microvascular complications and proliferation ofextracellular connective tissue in the lungs, leading to decline in lung function in arestrictive pattern. Interstitial lung disease (ILD) includes a diverse group ofdisease conditions characterized by different degrees of inflammation and fibrosisin the pulmonary parenchyma. Idiopathic pulmonary fibrosis (IPF) is one of thecommon type of idiopathic interstitial pneumonia with a high mortality rate. IPFis characterized by chronic progressive fibrosis leading to progressive respiratoryfailure. In this review we focus on lung as the target organ in DM and theassociation of DM and ILD with special emphasis on IPF. 关键词：Diabetes mellitus Interstitial lung disease Idiopathic pulmonary fibrosis METFORMIN Diabetes complications Pulmonary function test Restrictive lung disease HYPERGLYCEMIA

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Interstitial lung disease and diabetes

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