A mouse model for SARS-CoV-2 infection by exogenous delivery of hACE2 using alphavirus replicon particles

查看全文 作　　者：Ya-Nan [1]Zhang;Xiao-Dan [1,2]Li;Zhe-Rui [1]Zhang;Hong-Qing [1]Zhang;Na [1]Li;Jing [1]Liu;Jia-Qi [1]Li;Hua-Jun [1]Zhang;Ze-Jun [3]Wang;Shuo [3]Shen;Zheng-Li [1]Shi;Hong-Ping [1]Wei;Zhi-Ming [1]Yuan;Han-Qing [1]Ye;Bo [1]Zhang

机构地区：[1]Key Laboratory of Special Pathogens and Biosafety,Wuhan Institute of Virology,Center for Biosafety Mega-Science,Chinese Academy of Sciences,Wuhan,Hubei,430071,China;[2]Hunan Normal University,School of Medicine,Changsha,Hunan,410081,China;[3]Wuhan Institute of Biological Products Co.Ltd.,No.1 Huangjin Industrial Park Road,Jiangxia District,Wuhan,Hubei,420115,China

出　　处：《Cell Research》索引2020年第30卷第11期,共3页

基　　金：This work was supported by the National Key Research and Development Program of China(2018YFA0507201);the National Natural Science Foundation of China(81702005). 摘　　要：Dear Editor,Since the outbreak of a novel coronavirus disease(COVID-19)in late 2019,it has spread rapidly and developed into a global pandemic.As of August 12,2020,more than 215 countries and territories around the world have reported more than 20.5 million confirmed COVID-19 cases with over 745,693 deaths(http://gffzz58cf6dffd44b443cs6pwfu5k6wcwc6kpb.ffgz.tsg.suse.edu.cn/coronavirus/#countries).Such harsh conditions urged scientists across the world to gear up to develop vaccines and antiviral drugs against COVID-19,which also lead to massive requirement for experimental animals. 关键词：DRUGS INFECTION MASSIVE

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A mouse model for SARS-CoV-2 infection by exogenous delivery of hACE2 using alphavirus replicon particles

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