Improving mechanical and antibacterial properties of PMMA via polyblend electrospinning with silk fibroin and polyethyleneimine towards dental applications

查看全文 作　　者：Ugur Yunus [1]Karatepe;Tugba [1]Ozdemir

机构地区：[1]Molecular Biology and Genetics Department,Tokat Gaziosmanpasa University,Tasliciftlik,Tokat,Turkey

出　　处：《Bioactive Materials》索引2020年第5卷第3期,共6页

基　　金：supported in part by Turkish Science and Technology Agency(TUBITAK,3001 program,217M910)(to T.O.). 摘　　要：Poly(methylmethacrylate)(PMMA)is a widely used material in dental applications,particularly as denture resins.Due to thermally unstable and wet oral cavity,the implanted PMMA based resins occasionally deform and grow bacterial biofilms at the interface between oral cavity and the biomaterial.Several strategies attempted earlier to improve the bacterial resistance and mechanical performance of PMMA.Poly(ethyleneimine)(PEI)is a hyperbranched cationic polymer shown earlier to improve antibacterial activity of resins but do not improve mechanical properties of the resins alone,while silk fibroin(SF)is a natural biopolymer with unique material properties.In this study,we combined SF and PEI towards development of antibacterial and mechanically superior PMMA based materials towards overcoming its drawbacks.Using polyblend electrospinning to combine SF,PEI and PMMA,we successfully developed intrinsically antibacterial and mechanically reinforced nanofiber mats.We propose that the resulting nanofiber mats have the potential to be incorporated into PMMA based denture resin materials to overcome the problems of patients and improve their quality of life. 关键词：Dental biomaterials Reinforced Bacterial resistance PEI SF

相关文献

参考文献（32）
引证文献（5）
耦合文献（0）

参考文献(32)

引证文献(5)

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

Improving mechanical and antibacterial properties of PMMA via polyblend electrospinning with silk fibroin and polyethyleneimine towards dental applications

参考文献(32)

引证文献(5)

用户提示