维普中文期刊产品整合服务

Osseointegration of porous titanium and tantalum implants in ovariectomized rabbits:A biomechanical study

查看全文 作　　者：Stanislav [1]Bondarenko;Volodymyr [1]Filipenko;Michael [2]Karpinsky;Olena [2]Karpinska;Gennadiy [3]Ivanov;Valentyna [4]Maltseva;Ahmed Amine [1]Badnaoui;Ran [5]Schwarzkopf 高影响力作者 机构地区：[1]Department of Joint Pathology,Sytenko Institute of Spine and Joint Pathology,Kharkiv 61124,Ukraine;[2]Department of Biomechanics,Sytenko Institute of Spine and Joint Pathology,Kharkiv 61124,Ukraine;[3]Department of Experimental Pathology,Sytenko Institute of Spine and Joint Pathology,Kharkiv 61124,Ukraine;[4]Morphology of Connective Tissue Department,Sytenko Institute of Spine and Joint Pathology,Kharkiv 61124,Ukraine;[5]Department of Orthopedic Surgery,NYU Langone Orthopedic Hospital,Hospital for Joint Diseases,New York,NY 10003,United States高影响力机构 出　　处：《World Journal of Orthopedics》索引2021年第12卷第4期,共9页高影响力期刊 摘　　要：BACKGROUND Today,biological fixation of uncemented press-fit acetabular components plays an important role in total hip arthroplasty.Long-term stable fixation of these implants depends on the osseointegration of the acetabular cup bone tissue into the acetabular cup implant,and their ability to withstand functional loads.AIM To compare the strength of bone-implant osseointegration of four types of porous metal implants in normal and osteoporotic bone in rabbits.METHODS The study was performed in 50 female California rabbits divided into nonovariectomized(non-OVX)and ovariectomized groups(OVX)at 6 mo of age.Rabbits were sacrificed 8 wk after the implantation of four biomaterials[TTM,CONCELOC,Zimmer Biomet's Trabecular Metal(TANTALUM),and ATLANT]in a 5-mm diameter defect created in the left femur.A biomechanical evaluation of the femur was carried out by testing implant breakout force.The force was gradually increased until complete detachment of the implant from the bone occurred.RESULTS The breakout force needed for implant detachment was significantly higher in the non-OVX group,compared with the OVX group for all implants(TANTALUM,194.7±6.1 N vs 181.3±2.8 N;P=0.005;CONCELOC,190.8±3.6 N vs 180.9±6.6 N;P=0.019;TTM,186.3±1.8 N vs 172.0 N±11.0 N;P=0.043;and ATLANT,104.9±7.0 N vs 78.9 N±4.5 N;P=0.001).In the OVX group,The breakout forces in TANTALUM,TTM,and CONCELOC did not differ significantly(P=0.066).The breakout force for ATLANT in the OVX group was lower by a factor of 2.3 compared with TANTALUM and CONCELOC,and by 2.2 compared with TTM(P=0.001).In the non-OVX group,the breakout force for ATLANT was significantly different from all other implants,with a reduction in fixation strength by a factor of 1.9(P=0.001).CONCLUSION TANTALUM,TTM,and CONCELOC had equal bone-implant osseointegration in healthy and in osteoporotic bone.ATLANT had significantly decreased osseointegration(P=0.001)in healthy and in osteoporotic bone. 关 键 词：Animals Bone-implant interface Osteoporosis FEMUR TANTALUM Titanium
相关文献

参考文献(27)

引证文献(1)

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1　渝公网安备 50019002500403号　违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费