Fulminant myocarditis:a comprehensive review from etiology to treatments and outcomes

查看全文 作　　者：Weijian [1]Hang;Chen [1]Chen;John [2]M.Seubert;Dao Wen [1]Wang

机构地区：[1]Division of Cardiology,Department of Internal Medicine,and Hubei Key Laboratory of Genetics and Molecular Mechanisms of Cardiological Disorders,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China;[2]Faculty of Pharmacy and Pharmaceutical Sciences University of Alberta,Edmonton,Alberta T6G 2E1,Canada

出　　处：《Signal Transduction and Targeted Therapy》索引2020年第5卷第1期,共15页

基　　金：supported by grants from the National Natural Science Foundation of China(91839302,81630010,and 81790624);Tongji Hospital Clinical Research Flagship Program(2019CR207);JMS is support by a grant from the Canadian Institutes of Health Sciences(FRN156393). 摘　　要：Fulminant myocarditis(FM)is characterized by a rapid progressive decline in cardiac function and a high mortality rate.Since the first report of FM patients in the 1980s,several clinical trials and research studies have been published increasing our knowledge regarding FM.Currently,the diagnosis of FM depends on various techniques including electrocardiography,echocardiography,endomyocardial biopsy,and cardiac magnetic resonance.The development of mechanical circulation support(MCS)devices and progress in our understanding of the pathophysiological mechanisms underlying FM,treatment regimens have evolved from simple symptomatic treatment to a life support-based comprehensive treatment approach.The core mechanism underlying the development of FM is the occurrence of an inflammatory cytokine storm.This review provides a comprehensive account of the current understanding of FM pathophysiology and knowledge regarding its etiology,pathophysiology,treatments,and outcomes. 关键词：ETIOLOGY MYOCARDITIS treatment

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Fulminant myocarditis:a comprehensive review from etiology to treatments and outcomes

参考文献(155)

引证文献(45)

耦合文献(75)

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