Hyperbaric oxygen therapy as a complementary treatment for radiation proctitis:Useless or useful?-A literature review

查看全文 作　　者：Diogo Alpuim [1,2,3,4]Costa;Carla Espiney [3,5]Amaro;Ana [6]Nunes;Joana Santos [2,7]Cardoso;Pedro Modas [2,3,8]Daniel;Isabel [2,3,9]Rosa;João Vieira [2]Branco

机构地区：[1]Department of Haematology and Oncology,CUF Oncologia,Lisboa 1998-018,Portugal;[2]Centro de Medicina Subaquática e Hiperbárica(CMSH),Portuguese Navy,Lisboa 1649-020,Portugal;[3]Centro de Investigação Naval(CINAV),Portuguese Navy,Base Naval do Alfeite,Almada 2810-001,Portugal;[4]OVA Medical School,Faculdade de Ciências Médicas,Lisboa 1169-056,Portugal;[5]Department of Otorhinolaryngology,Hospital das Forças Armadas(HFAR),Lisboa 1649-020,Portugal;[6]Department of Gastroenterology,Hospital das Forças Armadas(HFAR),Lisboa 1649-020,Portugal;[7]Department of Vascular Surgery,Centro Hospitalar Universitário de Lisboa Central,Hospital de Santa Marta,Lisboa 1169-024,Portugal;[8]Department of Intensive Care Unit,Hospital das Forças Armadas(HFAR),Lisboa 1649-020,Portugal;[9]Department of General Surgery,Hospital das Forças Armadas(HFAR),Lisboa 1649-020,Portugal

出　　处：《World Journal of Gastroenterology》索引2021年第27卷第27期,共16页

摘　　要：Radiotherapy(RT)is the backbone of multimodality treatment of more than half of cancer cases.Despite new modern RT techniques,late complications may occur such as radiation proctitis(RP).The natural history of RP is unpredictable.Minor symptoms may resolve spontaneously or require conservative treatment.On the other hand,for similar and uncomplicated clinical contexts,symptoms may persist and can even be refractory to the progressive increase in treatment measures.Over the last decades,an enormous therapeutic armamentarium has been considered in RP,including hyperbaric oxygen therapy(HBOT).Currently,the evidence regarding the impact of HBOT on RP and its benefits is conflicting.Additional prospective and randomised studies are necessary to validate HBOT’s effectiveness in the‘real world’clinical practice.This article reviewed the relevant literature on pathophysiology,clinical presentation,different classifications and discuss RP management including a proposal for a therapeutic algorithm with a focus on HBOT. 关键词：Radiation proctitis Radiation proctopathy RADIOTHERAPY Radio-induced lesion Late radiation tissue injury Delayed radiation injury Late sequelae Hyperbaric oxygen therapy Hyperbaric oxygen Review

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Hyperbaric oxygen therapy as a complementary treatment for radiation proctitis:Useless or useful?-A literature review

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