Incidence and outcomes of intracerebral haemorrhage with mechanical compression hydrocephalus

查看全文 作　　者：Bryce [1]Owen;Omar [2]Akbik;Michel [3]Torbey;Herbert [4]Davis;Andrew P [2]Carlson

机构地区：[1]School of Medicine,University of New Mexico School of Medicine,Albuquerque,New Mexico,USA;[2]Neurosurgery,University of New Mexico,Albuquerque,New Mexico,USA;[3]Neurology,University of New Mexico,Albuquerque,New Mexico,USA;[4]Division of Epidemiology,Biostatistics,and Preventive Medicine,University of New Mexico,Albuquerque,New Mexico,USA

出　　处：《Stroke & Vascular Neurology》索引2021年第6卷第3期,共9页

摘　　要：Introduction Intracerebral haemorrhage(ICH)within deep structures adjacent to the third ventricle is associated with worse outcomes when compared with lobar ICH due to the critical role of deep nuclei in normal neurological functioning.New evidence suggests another contributing factor to poor outcome is obstruction of cerebrospinal fluid outflow by clot burden causing mechanical compression of the third ventricle.The authors reviewed the incidence and outcomes of mechanical compression ICH in order to identify this high-risk group which may potentially benefit from minimally invasive evacuation.Methods Patients with spontaneous,non-traumatic,supratentorial ICH were identified retrospectively over a 30-month period.CT imaging was reviewed to assess location of the ICH,volume of the ICH,presence of hydrocephalus requiring external ventricular drain(EVD)placement,and time to clearing of the third ventricle.Hydrocephalus was then categorised as due to‘primarily intraventricular haemorrhage(IVH)’,‘primarily mechanical compression’or‘mixed’.Functional outcomes at discharge were assessed using the modified Rankin Score(mRS).Results 287 patients met inclusion criteria,of which 39(13.5%)patients developed hydrocephalus that required EVD.EVD patients had significantly higher mRS at discharge(p≤0.001)when compared with the non-EVD group.Lobar location was associated with lower odds of poor outcome compared with thalamic location(OR 0.107-0.560).Mechanical compression hydrocephalus was associated with poor outcome when compared with the primary IVH hydrocephalus subgroup(p=0.037)as well as longer time to clearing of the third ventricle(p=0.006).Conclusions Mechanical obstruction requiring EVD occurs in approximately(21/287)7.3%of all patients with spontaneous supratentorial ICH.It is unknown if the worse morbidity in these subjects is purely related to damage to deep structures surrounding the third ventricle or if secondary damage from hydrocephalus could be mitigated with targeted minimally invasive clot evacuation. 关键词：HYDROCEPHALUS DAMAGE primarily

相关文献

参考文献（20）
引证文献（2）
耦合文献（506）

参考文献(20)

引证文献(2)

耦合文献(506)

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

Incidence and outcomes of intracerebral haemorrhage with mechanical compression hydrocephalus

参考文献(20)

引证文献(2)

耦合文献(506)

用户提示