Present and future management of viral hepatitis

查看全文 作　　者：Rocío González [1]Grande;Inmaculada Santaella [1]Leiva;Susana López [1]Ortega;Miguel Jiménez [1]Pérez

机构地区：[1]UGC de Aparato Digestivo.Unidad de Hepatología-Trasplante Hepático,Hospital Regional Universitario de Málaga,Málaga 29010,Spain

出　　处：《World Journal of Gastroenterology》索引2021年第27卷第47期,共22页

摘　　要：Viral hepatitis can result in important morbidity and mortality,with its impact on health conditioned by the specific type of hepatitis,the geographical region of presentation and the development and access to new drugs,among other factors.Most acute presentation forms are self-limiting and may even go unnoticed,with just a small percentage of cases leading to acute liver failure that may necessitate transplantation or even cause the death of the patient.However,when they become chronic,as in the case of hepatitis B virus and C virus,unless they are diagnosed and treated adequately they may have severe consequences,like cirrhosis or hepatocarcinoma.Understanding of the mechanisms of transmission,the pathogenesis,the presence of vaccinations and the development over recent years of new highly-efficient,potent drugs have meant that we are now faced with a new scenario in the management of viral hepatitis,particularly hepatitis B virus and hepatitis C virus.The spectacular advances in hepatitis C virus treatment have led the World Health Organization to propose the objective of its eradication by 2030.The key aspect to achieving this goal is to ensure that these treatments reach all the more vulnerable population groups,in whom the different types of viral hepatitis have a high prevalence and constitute a niche that may perpetuate infection and hinder its eradication.Accordingly,microelimination programs assume special relevance at the present time. 关键词：Hepatitis viral Diagnosis Treatment Trend direct-acting antivirals Inhibiting recycling

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Present and future management of viral hepatitis

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