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SIRT1 Mediates Sestrin1-Induced Improvement in Hepatic Insulin Resistance

查看全文 作  者:GENG [1]Chao;XUE [1]Yuan;YANG Jia [2]Hui;GAO Ming [1]Yue;ZHAO [1]Wei;LI Chun [1]Mei;XIE Xiang [1]Hong;ZHANG Wei [2]Hong;ZHANG Hua [3]Bing;FANG Fu [1]De;YAO [2]Hong;LIU Xiao [1]Jun 高影响力作者 机构地区:[1]State Key Laboratory of Medical Molecular Biology,Institute of Basic Medical Sciences Chinese Academy of Medical Sciences&School of Basic Medicine Peking Union Medical College,Beijing 100005,China;[2]Department of Microbiology and Immunology,Shanxi Medical University,Taiyuan 030001,Shanxi,China;[3]Department of Biochemistry and Molecular Biology,School of Basic Medicine,Anhui Medical University,Hefei 230032,Anhui,China高影响力机构 出  处:《Biomedical and Environmental Sciences》索引2022年第35卷第1期,共5页高影响力期刊 基  金:supported by the grants from National Natural Science Foundation of China[Grants No.31371191];Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences[CIFMS2017-I2M-1-008,CIFMS2021-1-I2M-016]。 摘  要:Mitochondria are important intracellular organelles that carry out oxidative phosphorylation,synthesize ATP,and provide energy for cell activities.Mitochondrial dysfunction can affect the normal function of the entire cell and is thought to be a major risk factor in the onset and progression of some diseases associated with chronic inflammation and insulin resistance[1]. 关 键 词:SIRT1 INFLAMMATION HEPATIC
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