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Recombinant protein subunit vaccine booster following two-dose inactivated vaccines dramatically enhanced anti-RBD responses and neutralizing titers against SARS-CoV-2 and Variants of Concern

查看全文 作  者:Jingwen [1]Ai;Haocheng [1]Zhang;Qiran [1]Zhang;Yi [1]Zhang;Ke [1]Lin;Zhangfan [1]Fu;Jieyu [1]Song;Yuanhan [1]Zhao;Mingxiang [1]Fan;Hongyu [1]Wang;Chao [1]Qiu;Yang [1]Zhou;Wenhong [1,2,3]Zhang 高影响力作者 机构地区:[1]Department of Infectious Diseases,National Medical Center for Infectious Diseases,Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response,Huashan Hospital,Shanghai Medical College,Fudan University,Shanghai,China;[2]National Clinical Research Center for Aging and Medicine,Huashan Hospital,Fudan University,Shanghai,China;[3]Key Laboratory of Medical Molecular Virology(MOE/MOH)Shanghai Medical College,Fudan University,Shanghai,China高影响力机构 出  处:《Cell Research》索引2022年第32卷第1期,共4页高影响力期刊 基  金:supported by the National Natural Science Foundation of China(82041010);the Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response(20dz2260100);the Key Discipline Construction Plan from Shanghai Municipal Health Commission(GWV-10.1-XK01). 摘  要:Dear Editor,As of October,2021,SARS-CoV-2 has infected more than 230 million people;promoting roll-out vaccinations could help build herd immunity for the pandemic.However,the waning of antibody in magnitude and decreased protective efficacy in multiple types of vaccines have been reported. 关 键 词:RBD protective NEUTRAL
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