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T cell immune responses to SARS-CoV-2 and variants of concern(Alpha and Delta)in infected and vaccinated individuals

查看全文 作  者:Stanley [1]C.Jordan;Bong-Ha [1]Shin;Terry-Ann [1]M.Gadsden;Maggie [1]Chu;Anna [1]Petrosyan;Catherine [2]N.Le;Rachel [2]Zabner;Jillian [2]Oft;Isabel [2]Pedraza;Susan [3]Cheng;Ashley [1]Vo;Noriko [1]Ammerman;Jasmine [4]Plummer;Shili [1]Ge;Max [1]Froch;Anders [5]Berg;Mieko [1]Toyoda;Ruan [1]Zhang 高影响力作者 机构地区:[1]Comprehensive Transplant Center,Transplant Immunology Laboratory,Cedars-Sinai Medical Center,Los Angeles,CA,USA;[2]Division of Infectious Diseases,Cedars-Sinai Medical Center,Los Angeles,CA,USA;[3]Department of Cardiology,Cedars-Sinai Medical Center,Los Angeles,CA,USA;[4]Department of Bioinformatics&Functional Genomics,Cedars-Sinai Medical Center,Los Angeles,CA,USA;[5]Department of Pathology&Laboratory Medicine,Cedars-Sinai Medical Center,Los Angeles,CA,USA高影响力机构 出  处:《Cellular & Molecular Immunology》索引2021年第18卷第11期,共3页高影响力期刊 摘  要:Our understanding of immune responses to SARS-CoV-2 and variants of concern(VOCs)has been primarily acquired through analysis of Spike-specific IgG responses.However,a more comprehensive understanding of the breadth and longevity of immune responses after infection and vaccination requires analysis of cellular immunity.Herein,we report on T cell immunity in infected and vaccinated individuals,identifying CD4+/CD8+T cell cytokine responses to SARS-CoV-2 and variant peptides(Alpha,B.1.1.7 and Delta,B.1.617.2). 关 键 词:ALPHA INFECTED IMMUNITY
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