Effects of phosvitin phosphopeptide-Ca complex prepared by efficient enzymatic hydrolysis on calcium absorption and bone deposition of mice

查看全文 作　　者：Mengdie [1]Zhao;Dong Uk [2]Ahn;Songming [1]Li;Wei [1]Liu;Shengwei [3]Yi;Xi [1]Huang

机构地区：[1]National Research and Development Center for Egg Processing,College of Food Science and Technology,Huazhong Agricultural University,Wuhan 430070,China;[2]Animal Science Department,Iowa State University,Ames 50011,USA;[3]Chongqing Institute for Food and Drug Control,Chongqing 401121,China

出　　处：《Food Science and Human Wellness》索引2022年第11卷第6期,共10页

基　　金：supported by the General Program of National Natural Science Foundation of China(32072237);the Hubei Provincial Natural Science Foundation of China(2020CFB583);Fundamental Research Funds for the Central Universities(2662020SPPY006)。 摘　　要：Phosvitin(PV)was treated with high-temperature,mild pressure(HTMP),and enzyme combination,and then phosvitin phosphopeptides-calcium(PPP-Ca)complexes were prepared.The low-calcium specific pathogen free-Kunming(SPF-KM)mice were used to determine the effect of PPP-Ca complexes on intestinal calcium absorption and their utilization for bone formation.The serum calcium content was the highest with the HTMP-Enz-PPP-Ca treatment(2.19 mmol/L),and it significantly down-regulated the abnormal elevation of serum alkaline phosphatase(AKP)caused by calcium deficiency.The low-calcium control group had the lowest calcium deposited to the femur(80.41 mg/g)and the lowest femur bone mineral density(BMD)(0.17 g/cm^(3)),while HTMP-Enz-PPP-Ca significantly improved bone calcium content(94.33 mg/g)and BMD(0.29 g/cm^(3)).The micro-computed tomography(MCT)images showed that the femur with the normal control,PV-Ca,and HTMP-Enz-PPP-Ca treatments had a more compact,complete,and thicker trabecular network than the low-calcium and CaCl_(2)treatments.These results indicated that the organic calcium(HTMP-Enz-PPP-Ca)promoted calcium absorption and bone deposition,and the effect of HTMP-Enz-PPP-Ca was better than the inorganic CaCl_(2). 关键词：Phosvitin phosphopeptide(PPP)-Ca complex SPF KM mice Calcium absorption Bone formation

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Effects of phosvitin phosphopeptide-Ca complex prepared by efficient enzymatic hydrolysis on calcium absorption and bone deposition of mice

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