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Disease profile and plasma neutralizing activity of postvaccination Omicron BA.1 infection in Tianjin,China:a retrospective study

查看全文 作　　者：Hong [1]Zheng;Yunlong [2,3]Cao;Xiaosu [4]Chen;Fengmei [5]Wang;Ye [4]Hu;Weiliang [3]Song;Yangyang [6]Chai;Qingqing [2]Gu;Yansong [4]Shi;Yingmei [7]Feng;Shuxun [8]Liu;Yan [1]Xie;Xiaoliang Sunney [2,3]Xie;Wentao [1]Jiang;Zhongyang [1]Shen 高影响力作者 机构地区：[1]Organ Transplant Center,NHC Key Laboratory for Critical Care Medicine,Tianjin First Central Hospital,Nankai University,Tianjin,China;[2]Changping Laborarty,Beijing,China;[3]Biomedical Pioneering Innovation Center(BIOPIC),Peking University,Beijing,China;[4]Frontier Research Center for Cell Response,Institute of Immunology,College of Life Sciences,Nankai University,Tianjin,China;[5]Institute of Hepatobiliary Disease,Tianjin Third Central Hospital,Tianjin,China;[6]Department of Immunology,Center for Immunotherapy,Institute of Basic Medical Sciences,Chinese Academy of Medical Sciences,Beijing,China;[7]Beijing Youan Hospital,Capital Medical University,Beijing,China;[8]National Key Laboratory of Medical Immunology,Institute of Immunology,Navy Medical University,Shanghai,China高影响力机构 出　　处：《Cell Research》索引2022年第32卷第8期,共4页高影响力期刊 基　　金：funded by Changping Laboratory(CPL-1233);the Emergency Key Program of Guangzhou Laboratory(EKPG21-30-3);sponsored by Ministry of Science and Technology of People’s Republic of China. 摘　　要：Dear Editor,SARS-CoV-2 Omicron variant BA.1 first emerged on the Chinese mainland on January 8,2022,in Tianjin and caused a large wave of infections.1 Four rounds of mass testing of its~14 million residents were launched on January 9,12,15,and 20,respectively.As of February 7,2022,a total of 430 individuals were tested positive for Omicron BA.1,with no new infections detected for the following 16 days.In the Chinese mainland,the most delivered vaccines are inactivated vaccines.As of January 8,2022,up to 93.2%of Tianjin’s residents had been vaccinated with at least one dose.2 We investigated the protection conferred by vaccination against Omicron BA.1 by examining the breakthrough infections among vaccinees as compared with unvaccinated cases.Our study population comprised all 430 cases during the outbreak of Omicron BA.1 in Tianjin. 关 键 词：RESIDENTS MAINLAND BREAKTHROUGH
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