Correlation of Ferroptosis and Other Types of Cell Death in Neurodegenerative Diseases

查看全文 作　　者：Xiaoting [1]Dang;Xuejie [1]Huan;Xixun [1]Du;Xi [1]Chen;Mingxia [1]Bi;Chunling [1]Yan;Qian [1]Jiao;Hong [1]Jiang

机构地区：[1]Department of Physiology,Shandong Provincial Key Laboratory of Pathogenesis,Prevention of Neurological Disorders,State Key Disciplines:Physiology,School of Basic Medicine,Qingdao University,Qingdao,266071,China

出　　处：《Neuroscience Bulletin》索引2022年第38卷第8期,共15页

基　　金：We gratefully acknowledge financial support from the National Natural Science Foundation of China(82071429 and 32171131);Shandong Province Natural Science Foundation(ZR2019ZD31,ZR2020MC072,and ZR2020QH125);Innovative Research Team of High-level Local Universities in Shanghai,China. 摘　　要：Ferroptosis is defined as an iron-dependent,non-apoptotic cell death pathway,with specific morphological phenotypes and biochemical changes.There is a growing realization that ferroptosis has significant implications for several neurodegenerative diseases.Even though ferroptosis is different from other forms of programmed death such as apoptosis and autophagic death,they involve a number of common protein molecules.This review focuses on current research on ferroptosis and summarizes the cross-talk among ferroptosis,apoptosis,and autophagy that are implicated in neurodegenerative diseases.We hope that this information provides new ideas for understanding the mechanisms and searching for potential therapeutic approaches and prevention of neurodegenerative diseases. 关键词：Ferroptosis APOPTOSIS Autophagic death Neurodegenerative diseases

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Correlation of Ferroptosis and Other Types of Cell Death in Neurodegenerative Diseases

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