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Biogenesis of autophagosomes from the ERGIC membrane system

查看全文 作  者:Yaping [1]Han;Shulin [1]Li;Liang [1]Ge 高影响力作者 机构地区:[1]The State Key Laboratory of Membrane Biology,Tsinghua University-Peking University Joint Center for Life Sciences,School of Life Sciences,Tsinghua University,Beijing 100084,China高影响力机构 出  处:《Journal of Genetics and Genomics》索引2023年第50卷第1期,共4页高影响力期刊 基  金:funded by Beijing Natural Science Foundation(JQ20028);the National Natural Science Foundation of China(32130023,91854114,32061143009);Ministry of Science and Technology of the People’s Republic of China(2019YFA0508602,2021YFA0804802)。 摘  要:Introduction Macroautophagy(hereafter referred as autophagy)is a process of cellular self-degradation.In response to nutrient deprivation or other stimuli,a nascent double-membrane autophagosome,encapsulating intracellular materials or damaged organelles,is generated.The autophagosome is transported toward and eventually fuses with the lysosome(or the vacuole in yeast and plant cells). 关 键 词:ERGIC COPII vesicle Autophagosome biogenesis Autophagy ERES
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