Giant dedifferentiated liposarcoma of the gastrocolic ligament:A case report

查看全文 作　　者：Assamoi Brou Fulgence [1,2]Kassi;Kacou Sebastien [1,2]Yenon;Fian Marc Herve [2]Kassi;Adja Jacob [2]Adjeme;Khader Morel [2]Diarra;Cynthia Bombet-[2]Kouame;Marcellin [2]Kouassi 机构地区：[1]Surgery and Surgical Specialities,Medical Sciences Training and Research Unit,Abidjan Felix Houphouet-Boigny University,Abidjan 01 BP V 34,Cote d'Ivoire;[2]Surgery and Surgical Specialities,Digestive Surgery Unit,University Hospital of Cocody,Abidjan 01 BP V13,Cote d'Ivoire 出　　处：《World Journal of Gastrointestinal Surgery》索引2023年第15卷第10期,共6页 摘　　要：BACKGROUND Dedifferentiated liposarcoma(DDLS)has a worse prognosis and occurs most commonly in the retroperitoneal region and rarely in the intraperitoneal region.Histological diagnosis was revolutionized by the combined contributions of histoimmuno-chemistry and molecular biology.Aside from surgery,there is no consensus on the optimal treatment for this chemoresistant cancer.CASE SUMMARY A thirty-year-old black female presented with a large painful abdominal mass occupying nearly the entire abdomen and progressive weight loss was admitted for surgery.Abdominal computed tomography showed a large heterogeneous mass of the mesentery that was sized 18 cm×16 cm in size and had heterogeneous contrast enhancement.During laparotomy,en bloc excision of the large and multilobulated gastrocolic ligament mass was performed.The initial postoperative histopathological diagnosis was undifferentiated sarcoma.Finally,the results of immunohistochemistry and molecular biology allowed us to confirm the diagnosis of DDLS.The tumour followed an aggressive evolution with diffuse metastasis,causing the death of the patient less than 5 mo after the operation.CONCLUSION Dedifferentiated liposarcomas are rare tumours that typically originate in the retroperitoneum but may arise in unexpected locations. 关 键 词：Dedifferentiated liposarcoma Gastrocolic ligament mass En bloc excision IMMUNOHISTOCHEMISTRY Molecular biology Worse prognosis Case report