A metabolome atlas of mouse brain on the global metabolic signature dynamics following short-term fasting

查看全文 作　　者：Yaping [1]Shao;Zhenfa [1]Fu;Yanfeng [2]Wang;Zhaofei [1]Yang;Yushan [1]Lin;Song [1]Li;Cheng [1]Cheng;Min [1]Wei;Zheyi [2]Liu;Guowang [2]Xu;Weidong [1,3]Le

机构地区：[1]Liaoning Provincial Key Laboratory for Research on the Pathogenic Mechanisms of Neurological Diseases,The First Affliated Hospital,Dalian Medical University,193 Lianhe Road,116021 Dalian,China;[2]CAS Key Laboratory of Separation Science for Analytical Chemistry,Dalian Institute of Chemical Physics,Chinese Academy of Sciences,457 Zhongshan Road,116023 Dalian,China;[3]Institute of Neurology,Sichuan Academy of Medical Science-Sichuan Provincial Hospital,Medical School of UESTC,611731 Chengdu,China

出　　处：《Signal Transduction and Targeted Therapy》索引2023年第8卷第10期,共12页

基　　金：This work was supported by the National Natural Science Foundation of China(NSFC 22004013,82271524,and 21934006);Doctoral Scientific Research Foundation of the Liaoning Science and Technology Department(2020-BS-200);the Central Guidance on Local Science and Technology Development Fund of Dalian Science and Technology Bureau. 摘　　要：Calorie restriction(CR)or a fasting regimen is considered one of the most potent non-pharmacological interventions to prevent chronic metabolic disorders,ameliorate autoimmune diseases,and attenuate aging.Despite efforts,the mechanisms by which CR improves health,particularly brain health,are still not fully understood.Metabolic homeostasis is vital for brain function,and a detailed metabolome atlas of the brain is essential for understanding the networks connecting different brain regions. 关键词：FASTING HOMEOSTASIS diseases

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A metabolome atlas of mouse brain on the global metabolic signature dynamics following short-term fasting

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