Relationship between obesity and cardiovascular risk factors in elderly Chinese subjects

查看全文 作　　者：G Neil [1]THOMAS;[1]赵海潞;[1]马艳青;Wilson YS LEUNG;Juliana CN CHAN;Brian TOMLINSON;Julian AJH CRITCHLEY;[1]梁润成;[1]陈重娥;[1]汤宁信;[1]郭志良 机构地区：[1]香港中文大学医学院内科药物与治疗系临床药理学部 出　　处：《Chinese Medical Journal》索引2002年第6期,共3页 基　　金：supported by the Hong Kong Research Grants Council(grants CUHK 425/95M and CUHK 4095/00M and CUHK Strategic Researeh Programme 9702). 摘　　要：Objective To investigate the relative effects of degree and distribution of body fat with several cardiovascular disease (CVD) risk factors in elderly Chinese subjects.Methods One-hundred and thirty-five elderly Chinese individuals (age range, 60-65 y) without any history of significant renal, hepatic or cardiac disease were recruited. Seated blood pressure, anthropometric and fasting plasma biochemical parameters were measured. Student’s t-test was used to compare the differences in biochemical and anthropometric markers between cohorts.Results Males were heavier (64.6±8.6, 57.2±8.2?kg, P<0.001), taller (1.65±0.06, 1.51± 0.05 m, P<0.001) and their greater body fat was predominantly deposited centrally (Waist-to-hip ratio, 0.91±0.06, 0.88±0.07, P<0.05). Females were more generally obese with increased body mass index (BMI, 23.8±4.6, 25.0±3.5 kg/m 2, P<0.05) and percentage body fat [26.3% (24.5%-28.1%) vs 37.2% (36.0%-38.9%), P<0.001] than the males. However, despite an 11% higher proportion of body fat in females, no significant differences were identified in blood pressure, lipid profile, indices of insulin resistance or albumin-to-creatinine ratios.Conclusion It is likely that central adiposity contributes disproportionately to these metabolic disorders in males even though they are much leaner than elderly Chinese females. 关 键 词：老年 中国人 肥胖 危险因素 性别