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| 1 | Synthesis, Characterization and X-ray Structure of N-(4-bromobutanoyl-N'-(2-3-and 4-methylphenyl)thiourea显示文摘N-4-(bromobutanoyl)-N'-(o-, m- and p-tolyl)thioureas 3a, 3b and 3c respectively, were synthesized by the reaction of 4-bromobutanoylisothiocyanate with p-, m- and o-toludine. The products were characterized by IR, and NMR spectroscopic techniques. The two carbonoylthiourea isomers N-(4-bromobutanoyl)-N'-(3-methylphenyl)thiourea(3b) and N-(4-bromobutanoyl)-N'-(4-methylphenyl)thiourea(3c) were obtained in crystalline form by recrystallization from DMSO. Xray crystallographic studies showed that both compounds 3b and 3c crystallize in triclinic system with space group of P1. The molecules adopt trans-cis configuration with respect to the positions of 4-bromobutanoyl and tolyl groups respectively, against the thiono C=S bond across their C–N bonds. The configuration is attributed by the intrahydrogen bond between the carbonyl oxygen and amide hydrogen atoms. Both crystal structures are stabilized by N–H···S intermolecular hydrogen bonds to form dimers and arranged along the b axis. | Hamza M Abosadiya Siti Aishah Hasbullah Bohari M Yamin | 2015 | Chinese Journal of Structural Chemistry2015，34，3： | 3 |
| 2 | Anthocyanins from Hibisscus Sabdariffa,Melastoma malabathricum and Ipomoea batatas and its color properties显示文摘 | Aishah B Nursabrina M Noriham A Norizzah AR Mohamad S H | 2013 | International Food Research Journal2013，20，2： | 1 |
| 3 | Serum levels of squamous cell carcinoma antigen and CA 125 in cervical intraepithelial neoplasia and invasive squamous cell carci- noma of the uterine cervix 显示文摘 | Looi M D Hatta M A Siti Aishah | 2011 | International Journal of Cancer Research2011，2，3： | 1 |
| 4 | Biodiesel fuel production from algae as renewable energy 显示文摘 | A B M SHARIF HOSSAIN AISHAH SALLEH AMRU NASRULHAQ BOYCE | 2008 | American Journal of Biochemistry and Biotechnology2008，4，3： | 1 |
| 5 | Alkabloids from Mitragyna speciosa 显示文摘 | Peter J H Aishah L Ikyan M S | 1991 | Phytochemistry1991，30，1： | 1 |
| 6 | Biodiesel fuel productiong from algae as re- newable energy 显示文摘 | A B M Sharif Hossain Aishah Salleh Amru Nasrulhaq Boyce | 2008 | American Journal of Biochemistry and Biotechnology2008，4，3： | 1 |
| 7 | Swyer syndrome in a Woman with pure 46,XY gonadal dysgenesis and a hypoplasticuterus显示文摘 | AZIDAH A NIKHAZLINA N AISHAH M | 2013 | Malays Fam Physician2013，8，2： | 1 |
| 8 | An overview of ionic liquids as solvents in biodiesel synthesis显示文摘 | Ahmad Hafiidz M F Nor Aishah S A | 2012 | Renewable and Sustainable Energy Reviews2012，16，8： | 1 |
| 9 | Assessment of genotoxicity and cytotoxicity of standardized aqueous extract from leaves of Erythroxylum cuneatum in human HepG2 and WRL68 cells line显示文摘Objective:To investigate the cytotoxicity and the genotoxicity of standardized aqueous of dry leaves of Erythroxylum cuneatum(E.cuneatum)in human HepG2 and WRL68 cells.Methods:The cytoloxicity of E.cuneatum extract was evaluated by both MTS and LDH assays.Genotoxicity study on E.cuneatum extract was assessed by the single cell gel electrophoresis(comet assay).The protective effect of E.cuneatum against menadione-induced cytotoxicity was also investigated.Results:Results from this study showed that E.cuneatum extract exhibited cytotoxic activities towards the cells with IC_(50)value of(125±12)and(125±14)μg/mL for HepG2and WRL68 cells respectively,after 72 h incubation period as determined by MTS assay.LDH leakage was detected at(251±19)and(199.5±12.0)μg/mL for HepG2 and WRL68 respectively.Genotoxicity study results showed that treatment with E.cuneatum up to 1 mg/mL did not cause obvious DNA damage in WRL68 and HepG2 cells.Addition of E.cunaetum did not show significant protection towards menadione in WRL68 and HepG2 Cells.Conclusions:E.cuneatum standardized aqueous extract might be developed in onler to establish new pharmacological possibilities for its application. | RK Wesam AN Ghanya HH Mizaton M ILham A Aishah | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，10： | 0 |
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