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| 1 | 西瓜果皮底色基因ClCGmenG的精细定位显示文摘目的与意义:西瓜是一种在世界范围内广泛种植的园艺作物,果皮颜色是西瓜重要的农艺性状.西瓜果皮颜色具有绿色(浅绿色到墨绿色)、黄色、灰白色等.西瓜果皮颜色是一种质量性状,但是其遗传规律和形成机制是有争议的.尽管文献中已报道多种关于西瓜皮色的遗传模型,但关于西瓜皮色的基因定位研究较少.通过2年的试验研究,西瓜果皮颜色(墨绿色和浅绿色)是由1个位于8号染色体末端的基因控制的,墨绿色对浅绿色是显性.本研究基于课题组遗传图谱关于果皮颜色的初定位结果,结合西瓜参考基因组(97103和Charleston Gray)的序列信息,旨在通过精细定位确定控制西瓜果皮颜色的候选基因,为西瓜分子遗传育种提供理论依据. | 李兵兵 刘文革 赵胜杰 豆峻岭 Ali Aslam Haileslassie Gebremeskel 高磊 何楠 路绪强 | 2019 | 中国瓜菜2019，32，8： | 6 |
| 2 | 不同葫芦科作物中瓜氨酸含量的比较显示文摘为了解瓜氨酸在不同葫芦科作物中的含量差异,以9种葫芦科作物为研究对象,分别测定了其果实、老叶、幼叶、根、茎中的瓜氨酸含量。结果表明,比较9种葫芦科作物的所有组织中的瓜氨酸含量,发现西瓜(Citrullus lanatus)果实中的瓜氨酸含量(w,后同)最高,可以达到1.40 g·kg^-1,其次是丝瓜(Luffa aegyptiaca)老叶中的瓜氨酸含量,为0.85 g·kg^-1,再次是苦瓜(Momordica charantia)老叶中的瓜氨酸含量,为0.66 g·kg^-1。比较不同葫芦科作物同一组织间瓜氨酸含量发现,不同作物果实中,西瓜的瓜氨酸含量最高,为1.40 g·kg^-1;茎中瓠瓜(Lagenaria siceraria)的瓜氨酸含量最高,为0.39 g·kg^-1;根中苦瓜的瓜氨酸含量最高,为0.43 g·kg^-1,幼叶中苦瓜的瓜氨酸含量最高,为0.47 g·kg^-1,而在老叶中丝瓜的瓜氨酸含量较高,为0.85 g·kg^-1。综上所述,葫芦科作物不仅在果实中含有瓜氨酸,其他组织也是潜在的瓜氨酸来源。 | ALI Aslam 王伟伟 何楠 路绪强 赵胜杰 朱红菊 刘文革 | 2020 | 中国瓜菜2020，33，6： | 4 |
| 3 | Elemental composition of rice using calibration free laser induced breakdown spectroscopy显示文摘In this paper, we apply laser induce breakdown spectroscopy (LIBS) to determine the elemental composition of different parts(root, stem and seed) of the rice plant and determine their weighted concentration using calibration free laser induced breakdown spectroscopy (CF-LIBS) technique. Ca, Fe and K are identified as major elements, while C, Ti, Mg, Si, Li, Ba, Sr, Cr, Na and Al as minor elements. We also detect the H-alpha line of hydrogen in the spectrum and determine the electron number density. The electron number density and its behavior as a function of laser energy, laser wavelength and the detector position are investigated. The plasma temperatures of samples are determined, and the validity of the assumption of the local thermodynamic equilibrium (LTE) is discussed. | Abdul Jabbar Mahmood Akhtar Arslan Ali Shaukat Mehmood Sidra Iftikhar Muhmmad Aslam Baig | 2019 | Optoelectronics Letters2019，15，1： | 4 |
| 4 | In vitro antioxidant,cytotoxic,thrombolytic activities and phytochemical evaluation of methanol extract of the A.philippense L.leaves显示文摘Objective:To study the leaves of Adiantum philippense L.for their antioxidant,cytotoxicity and thrombolytic activities and to perform phytochemical evaluation.Methods:In-vitro antioxidant activity of extract was studied using DPPH radical scavenging,reducing power,total phenol and total flavonoid content determination assays.The cytotoxic activity was determined using brine shrimp lethality bioassay,thrombolytic activity by clot disruption and phytochemical potential by qualitative analysis.Results:The antioxidant activity of the extracts was found promising.The reducing power of this crude extract increase with the increase of concentration;IC_(50)values of DPPH scavenging activity was(140.00±0.86)μg/mL as compared to ascorbic acid[IC_(50)(130.00±0.76)μg/mL];Total phenol and total flavonoids content were(148.26±0.24)mg/mL and(163.06±0.56)mg/mL respecnvely.In cytotoxicity assay the LC_(50)values of the sample was(106.41±0.78)μg/mL where as for standard vincristin sulphate was(08.50±0.24)μg/mL as a positive control and the extract shows(12.8611.02)%clot lytic whereas standard streptokinase shows(30.86+0.44%clot lytic activity in thrombolytic assay.The phytochemical evaluation indicates the presence of chemical constituents including carbohydrates,alkaloids,saponins,glycosides,flavonoids.Conclusions:This study shows that the methanol extract of leaves of Adiantum philippense L.has bioactivitv but further compound isolation is necessary to confirm the activities of individual compounds. | Mohammad Sekendar Ali Mohammad Ruhul Amin Chowdhury Mohammad Imtiaz Kamal Mohammad Aslam Hossain | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，6： | 3 |
| 5 | Vertical axis wind turbine – A review of various configurations and design techniques显示文摘 | Muhammad Mahmood Aslam Bhutta Nasir Hayat Ahmed Uzair Farooq Zain Ali Sh. Rehan Jamil Zahid Hussain | 2011 | Renewable and Sustainable Energy Reviews2011，，4： | 3 |
| 6 | Leonurus sibiricus L.(honeyweed):A review of its phytochemistry and pharmacology显示文摘Leonurus sibiricus is a herbaceous plant found in many countries in Asia and America.This plant is widely practiced as a remedy for the treatment of diabetes,menstrual irregularities,and bronchitis.The approval of therapeutic implications of any drugs depends on the well characterized mode of actions of the compounds.The bioactive compounds like diterpenes,triterpenes,flavonoids and phenolic acids in Leonurus sibiricus show analgesic,anti-inflammatory,anti-oxidant,anti-atherogenic and antihemorrhagic,anti-diabetic,anti-bacterial and allelopathic potency.Interestingly,the expression level of some genes is altered by the crude extract treatments,which are effective against cancers,diabetes and cardiovascular diseases where the molecular mechanisms are yet to be explored.Intriguingly,the extracts significantly induce nitric oxide production by endothelial nitric oxide synthase,a signaling molecule of vasodilation in combination with interferon-y indicating positive effect on atherosclerosis.Further investigations are required to unlock the effects of bioactive compounds found in extracts at clinical settings. | Abu Sayed AshraM Alam Shariful Islam Taif Ali Emdad Ullah Abu Zaffar Shibly Aslam Ali Mahdi Hasan-Olive | 2016 | Asian Pacific Journal of Tropical Biomedicine2016，6，12： | 2 |
| 7 | Reverse vaccinology assisted designing of multiepitope-based subunit vaccine against SARS-CoV-2显示文摘Background:Coronavirus disease 2019(COVID-19)linked with severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)cause severe illness and life-threatening pneumonia in humans.The current COVID-19 pandemic demands an effective vaccine to acquire protection against the infection.Therefore,the present study was aimed to design a multiepitope-based subunit vaccine(MESV)against COVID-19.Methods:Structural proteins(Surface glycoprotein,Envelope protein,and Membrane glycoprotein)of SARS-CoV-2 are responsible for its prime functions.Sequences of proteins were downloaded from GenBank and several immunoinformatics coupled with computational approaches were employed to forecast B-and T-cell epitopes from the SARS-CoV-2 highly antigenic structural proteins to design an effective MESV.Results:Predicted epitopes suggested high antigenicity,conserveness,substantial interactions with the human leukocyte antigen(HLA)binding alleles,and collective global population coverage of 88.40%.Taken together,276 amino acids long MESV was designed by connecting 3 cytotoxic T lymphocytes(CTL),6 helper T lymphocyte(HTL)and 4 B-cell epitopes with suitable adjuvant and linkers.The MESV construct was non-allergenic,stable,and highly antigenic.Molecular docking showed a stable and high binding affinity of MESV with human pathogenic toll-like receptors-3(TLR3).Furthermore,in silico immune simulation revealed significant immunogenic response of MESV.Finally,MEV codons were optimized for its in silico cloning into the Escherichia coli K-12 system,to ensure its increased expression.Conclusion:The MESV developed in this study is capable of generating immune response against COVID-19.Therefore,if designed MESV further investigated experimentally,it would be an effective vaccine candidate against SARS-CoV-2 to control and prevent COVID-19. | Muhammad Tahir ul Qamar Farah Shahid Sadia Aslam Usman Ali Ashfaq Sidra Aslam Israr Fatima Muhammad Mazhar Fareed Ali Zohaib Ling-Ling Chen | 2020 | Infectious Diseases of Poverty2020，9，5： | 2 |
| 8 | Recent Insights into Signaling Responses to Cope Drought Stress in Rice显示文摘Drought is one of the hot topics needing urgent attention in the current era of climate change.It massively disturbs the rice growth and productivity and is becoming a serious threat.The drought avoidance strategies in rice include stomatal closure,cellular adaptation and changes in root development.Moreover,the endogenous plant hormones(abscisic acid and jasmonic acid)and reactive oxygen species have paramount importance in drought tolerance in rice.The drought tolerance induces modification in biochemical,molecular and physiological properties of plants.At the molecular level,expression of several transcription-factors is modulated which further determine the activation of drought responsive gene families.Mitogen activated protein kinases and Ca signaling pathways initiate an array of signaling cascade for mediating the gene expression in rice.Approaches,conventional breeding methods combined with modern emerging techniques such as genetic engineering,to improve rice drought tolerance were discussed.This review provided recent insights into major regulatory factors against drought stress,signaling mechanisms and molecular engineering strategies(including conventional transgenic and recent genome editing approaches)to induce drought tolerance in rice. | Muhammad Mahran ASLAM Muhammad Abdul Rehman RASHID Mohammad Aquil SIDDIQUI Muhammad Tahir KHAN Fozia FARHAT Shafquat YASMEEN Imtiaz Ahmad KHAN Shameem RAJA Fatima RASOOL Mahboob Ali SIAL ZHAO Yan | 2022 | Rice science2022，29，2： | 2 |
| 9 | Esophageal varices on computed tomography and subsequent variceal hemorrhage显示文摘 | Ma Somsouk Katherine To’o Mujtaba Ali Eric Vittinghoff Benjamin M. Yeh Judy Yee Alex Monto John M. Inadomi Rizwan Aslam | 2014 | Abdominal Imaging2014，，2： | 1 |
| 10 | Flavonoid and cardenolide glycosides and a pentacyclic triterpene from the leaves of Nerium oleander and evaluation of cytotoxicity显示文摘 | Bina Shaheen Siddiqui Nasima Khatoon Sabira Begum Ahsana Dar Farooq Kehkashan Qamar Huma Aslam Bhatti Syed Kashif Ali | 2012 | Phytochemistry2012，，： | 1 |
| 11 | Intraparotid facial nerve schwannoma: a case report显示文摘 | Ali WM Aslam M Beg MH | 2011 | Int J Case Rep Image2011，2，8： | 1 |
| 12 | Bayesian estimation of the mixture of generalized exponential distribution: a versatile lifetime model in industrial processes 显示文摘 | ALI S ASLAM M KUNDU D | 2012 | Journal of the Chinese Institute of Industrial Engineers2012，29，4： | 1 |
| 13 | Chemical con-stituents of Centella asiatica 显示文摘 | SIDDIQUI B S ASLAM H ALI S T | 2007 | Journal of Asian NaturalProducts Research2007，9，4： | 1 |
| 14 | 西瓜果皮黄色的遗传及连锁标记的开发显示文摘目的与意义:果皮颜色作为一个重要的农艺性状,在不用物种中有不同的表型,西瓜果皮也有黑色、墨绿、绿色、黄色、白色等多种颜色.随着人民生活水平的提高,人们对特色的西瓜品种的需求日益增长,黄色果皮作为一个最直观的品质性状,越来越受到人们的喜爱.然而关于西瓜果皮黄色的遗传以及分子机理研究的相对较少,黄皮西瓜的育种工作大部分都是依靠传统的杂交育种方式,本实验通过传统杂交组合的配制,结合现代分子生物学技术,深入解析西瓜果皮黄色遗传模式,希望能够获得和西瓜果皮黄色的紧密连锁的分子标记,从而为今后的分子标记辅助育种提供帮助. | 豆峻岭 刘文革(编译) 路绪强 Aslam Ali 赵胜杰 张磊 何楠 匡汉晖 | 2019 | 中国瓜菜2019，32，8： | 1 |
| 15 | COVID-19 and comorbidities of hepatic diseases in a global perspective显示文摘The worldwide outbreak of coronavirus disease 2019(COVID-19) has challenged the priorities of healthcare system in terms of different clinical management and infection transmission, particularly those related to hepatic-disease comorbidities. Epidemiological data evidenced that COVID-19 patients with altered liver function because of hepatitis infection and cholestasis have an adverse prognosis and experience worse health outcomes. COVID-19-associated liver injury is correlated with various liver diseases following a severe acute respiratory syndrome-coronavirus type 2(SARS-CoV-2) infection that can progress during the treatment of COVID-19 patients with or without pre-existing liver disease. SARS-CoV-2 can induce liver injury in a number of ways including direct cytopathic effect of the virus on cholangiocytes/hepatocytes, immune-mediated damage, hypoxia, and sepsis. Indeed, immediate cytopathogenic effects of SARSCoV-2 via its potential target, the angiotensin-converting enzyme-2 receptor, which is highly expressed in hepatocytes and cholangiocytes, renders the liver as an extra-respiratory organ with increased susceptibility to pathological outcomes. But, underlying COVID-19-linked liver disease pathogenesis with abnormal liver function tests(LFTs) is incompletely understood. Hence, we collated COVID-19-associated liver injuries with increased LFTs at the nexus of pre-existing liver diseases and COVID-19, and defining a plausible pathophysiological triad of COVID-19, hepatocellular damage, and liver disease. This review summarizes recent findings of the exacerbating role of COVID-19 in pre-existing liver disease and vice versa as well as international guidelines of clinical care, management, and treatment recommendations for COVID-19 patients with liver disease. | Aqsa Ahmad Syeda Momna Ishtiaq Junaid Ali Khan Rizwan Aslam Sultan Ali Muhammad Imran Arshad | 2021 | World Journal of Gastroenterology2021，27，13： | 1 |
| 16 | 基于全基因组重测序构建西瓜高密度遗传图谱和果实相关性状的基因定位显示文摘目的与意义:遗传图谱是进行重要农艺性状QTL/基因定位、图位克隆、分子标记辅助育种等工作的重要工具.长期的人工选择使得栽培种西瓜的遗传基础进一步狭窄,使得高效可获得的分子标记成为限制西瓜高密度遗传图谱构建的重要因素.随着高通量测序技术的发展和西瓜参考基因组草图的组装完成,通过测序获得大量分子标记以构建高密遗传图谱成为可能.通过全基因重测序构建高密度遗传图谱,可以更快更准确的检测重组断点,开发大量适于遗传图谱构建的分子标记.最近几年,陆续有多张西瓜遗传图谱发表.但这些图谱大都基于简化基因组测序,遗传图谱的饱和度相对不足;作图群体多为临时性分离群体,不能进行重复试验,影响后续基因定位工作的准确性.笔者构建了重组自交系作为永久性作图群体,通过对其进行全基因组重测序构建了一张西瓜高密度遗传图谱,并对果皮颜色、种皮颜色和果实苦味3个性状进行了初定位,以期用于西瓜分子遗传育种等工作. | 李兵兵 刘文革 路绪强 豆峻岭 Ali Aslam 高磊 赵胜杰 何楠 | 2019 | 中国瓜菜2019，32，8： | 1 |
| 17 | Contribution of greenhouse gas emissions during cropping and fallow seasons on total global warming potential in mono-rice paddy soils显示文摘 | Md Mozammel Haque Sang Yoon Kim Muhammad Aslam Ali | 2012 | Plant Soil2012，，387： | 1 |
| 18 | Chemical constituents of Centella asiatica显示文摘 | Siddiqui BS Aslam H Ali ST | 2007 | J Asian Nat Prod Res2007，9，35： | 1 |
| 19 | Metal-catalyzed synthesis of ultralong tin dioxide nanobelts: Electrical and optical properties with oxygen vacancy-related orange emission显示文摘 | Faheem K. Butt Chuanbao Cao Tariq Mahmood Faryal Idrees Muhammad Tahir Waheed S. Khan Zulfiqar Ali Muhammad Rizwan M. Tanveer Sajad Hussain Imran Aslam Dapeng Yu | 2014 | Materials Science in Semiconductor Processing2014，，： | 1 |
| 20 | Carolid-eavermons fislula presenting with a red eye显示文摘 | Aslam SA Sallam A Ali N | 2010 | Emerg Med J2010，27，4： | 1 |
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