|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Outcomes and patients' perspectives of transition from paediatric to adult care in inflammatory bowel disease显示文摘AIM: To describe the disease and psychosocialoutcomes of an inflammatory bowel disease(IBD) transition cohort and their perspectives.METHODS: Patients with IBD, aged > 18 years, who had moved from paediatric to adult care within 10 years were identified through IBD databases at three tertiary hospitals. Participants were surveyed regarding demographic and disease specific data and their perspectives on the transition process. Survey response data were compared to contemporaneously recorded information in paediatric service case notes. Data were compared to a similar age cohort who had never received paediatric IBD care and therefore who had not undergone a transition process. RESULTS: There were 81 returned surveys from 46 transition and 35 non-transition patients. No statistically significant differences were found in disease burden, disease outcomes or adult roles and responsibilities between cohorts. Despite a high prevalence of mood disturbance(35%), there was a very low usage(5%) of psychological services in both cohorts. In the transition cohort, knowledge of their transition plan was reported by only 25/46 patients and the majority(54%) felt they were not strongly prepared. A high rate(78%) of discussion about work/study plans was recorded prior to transition, but a near complete absence of discussion regarding sex(8%), and other adult issues was recorded. Both cohorts agreed that their preferred method of future transition practices(of the options offered) was a shared clinic appointment with all key stakeholders. CONCLUSION: Transition did not appear to adversely affect disease or psychosocial outcomes. Current transition care processes could be optimised, with better psychosocial preparation and agreed transition plans. | Alice L Bennett David Moore Peter A Bampton Robert V Bryant Jane M Andrews | 2016 | World Journal of Gastroenterology2016，22，8： | 3 |
| 2 | Th1 cytokines promote T-cell binding to antigen-presenting cells via enhanced hyaluronan production and accumulation at the immune synapse显示文摘Hyaluronan(HA)production by dendritic cells(DCs)is known to promote antigen presentation and to augment T-cell activation and proliferation.We hypothesized that pericellular HA can function as intercellular‘glue’directly mediating T cell–DC binding.Using primary human cells,we observed HA-dependent binding between T cells and DCs,which was abrogated upon pre-treatment of the DCs with 4-methylumbelliferone(4-MU),an agent which blocks HA synthesis.Furthermore,T cells regulate HA production by DCs via T cell-derived cytokines in a T helper(Th)subset-specific manner,as demonstrated by the observation that cell-culture supernatants from Th1 but not Th2 clones promote HA production.Similar effects were seen upon the addition of exogenous Th1 cytokines,IL-2,interferon c(IFN-c)and tumor necrosis factor a(TNF-a).The critical factors which determined the extent of DC–T cell binding in this system were the nature of the pre-treatment the DCs received and their capacity to synthesize HA,as T-cell clones which were pre-treated with monensin,added to block cytokine secretion,bound equivalently irrespective of their Th subset.These data support the existence of a feedforward loop wherein T-cell cytokines influence DC production of HA,which in turn affects the extent of DC–T cell binding.We also document the presence of focal deposits of HA at the immune synapse between T-cells and APC and on dendritic processes thought to be important in antigen presentation.These data point to a pivotal role for HA in DC–T cell interactions at the IS. | Paul L Bollyky Stephen P Evanko Rebecca P Wu Susan Potter-Perigo S Alice Long Brian Kinsella Helena Reijonen Kelly Guebtner Brandon Teng Christina K Chan Kathy R Braun John A Gebe Gerald T Nepom Thomas N Wight | 2010 | Cellular & Molecular Immunology2010，7，3： | 3 |
| 3 | Phylogeny ofRubus (Rosaceae) based on nuclear ribosomal DNA internal transcribed spacer region sequences 显示文摘 | Alice L A Campbell C S | 1999 | Am JBot1999，86，： | 1 |
| 4 | EHects of grazing on commu- nity structure and productivity o{ a Uruguayan Grassland显示文摘 | Alice A Mart O Elsa L etal | 2005 | Plant Ecology2005，179，1： | 1 |
| 5 | Effect of grazing on community structure and productivity of a Uruguayan grassland显示文摘 | ALICE A MARTIN O ELSA L | 2005 | Plant Ecology2005，179，： | 1 |
| 6 | Evolution of the Fucaceae(Phaeophyceae)inferred from nrDNA-ITS显示文摘 | Serr?o E A Alice L A Brawley S H | 1999 | Journal of Phycology1999，35，2： | 1 |
| 7 | Comparing the Effects of Echoic Prompts and Echoic Prompts plus Modeled Prompts on Intraverbal Behavior显示文摘 | Valentino Amber L Shillingsburg M Alice Call Nathan A | 2012 | Journal of Applied Behavior Analysis2012，，45： | 1 |
| 8 | Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case–control studies显示文摘 | Celeste Leigh Pearce Claire Templeman Mary Anne Rossing Alice Lee Aimee M Near Penelope M Webb Christina M Nagle Jennifer A Doherty Kara L Cushing-Haugen Kristine G Wicklund Jenny Chang-Claude Rebecca Hein Galina Lurie Lynne R Wilkens Michael E Carney Mar | 2012 | Lancet Oncology2012，，： | 1 |
| 9 | Effect of grazing on community structure and productivity of a Uruguayan grassland显示文摘 | Alice A Martin O Elsa L | 2005 | Plant Ecology2005，179，： | 1 |
| 10 | A phylogeny of Chloridoideae (Poaceae)based on matk sequences显示文摘 | Hilu K W Alice L A | 2001 | Syst Bot2001，26，2： | 1 |
| 11 | Effects of pH on Properties of Wheat Gluten and Soy Protein Isolate Films显示文摘 | GENNADIOS A BRANDERBERG Alice H WELLER C L | 1993 | Journal of Agriculture and Food Chemistry1993，41，11： | 1 |
| 12 | The nucleoporin Nup 96 is required for proper expression of interferon-regulated proteins and functions 显示文摘 | Faria A M Levay A Wang Y M Alice O K Rosa M L | 2006 | Immunity2006，24，3： | 1 |
| 13 | How reliable is satellite navigation for aviation?Checking availability properties with probabilistic verification显示文摘 | YU L ZHAO G P ALICE A | 2015 | Reliability Engineering and System Safety2015，，144： | 1 |
| 14 | Evolution of the Fucaceae (Phaeophyceae) inferred from nrDNA-ITS 显示文摘 | Serrao E A Alice L A Brawley S H | 1999 | J Phycol1999，35，： | 1 |
| 15 | Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty (RECORD4): a randomised trial显示文摘 | Alexander GG Turpie Michael R Lassen Bruce L Davidson Kenneth A Bauer Michael Gent Louis M Kwong Fred D Cushner Paul A Lotke Scott D Berkowitz Tiemo J Bandel Alice Benson Frank Misselwitz William D Fisher | 2009 | The Lancet2009，，9676： | 1 |
| 16 | Plant carbohydrate scavenging through Ton B-dependent recep?tors:A feature shared by phytopathogenic and aquatic bacteria显示文摘 | SERVANE B DAMIEN M ALICE B MARTINE L CATHE?RINE G D JACQUES V EMMANUELLE L MATTHIEU A | 2007 | PLo S One2007，2，2： | 1 |
| 17 | Relative impact of fouling and cleaning on PVDF membrane hydraulic performances显示文摘 | Shima H Alice A Greg L | 2012 | Sep Purif Technol2012，90，： | 1 |
| 18 | Phylogeny of Rubus (Rosacean) based on nuclear ribosomal DNA internal transcribed spacer region sequences显示文摘 | ALICE L A CAMPBELL C S | 1999 | America Journal of Botany1999，86，1： | 1 |
| 19 | Angiosperm phylogeny based on matK sequence information显示文摘 | Powell L Alice A Evans R H | 2003 | American Journal of Botany2003，90，： | 1 |
| 20 | 2005, Effect of grazing on community structure and productivity of a Uruguayan grassland显示文摘 | ALICE A MARTIN O ELSA L | 2005 | Plant Ecology2005，179，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员