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| 1 | NEW TOXOPLASMA GONDII GENOTYPES ISOLATED FROM FREE-RANGE CHICKENS FROM THE FERNANDO DE NORONHA, BRAZIL: UNEXPECTED FINDINGS显示文摘 | Dubey J P Rajendran C Costa D G C Ferreira L R Kwok O C H Qu D Su C Marvulo M F V Alves L C Mota R A Silva J C R | 2010 | The Journal of Parasitology2010，，4： | 2 |
| 2 | 'Effect of tillage on fractal indices describing soil surface microrelief of a Brazilian Alfisol显示文摘 | Vi~lal'V~izquez E /Vliranda J G V Alves M C | 2006 | Geoderma2006，134，3： | 1 |
| 3 | Electoral Surveys' Influence on the Voting Processes: A Cellular Automata Model显示文摘 | Alves S G Oliveira N M Martins M L | 2002 | Physica A: Statistical Mechanics and Its Applications2002，316，14： | 1 |
| 4 | Simultaneous follow-up of mouse colon lesions by colonoscopy and endoluminal ultrasound biomicroscopy显示文摘AIM:To evaluate the potential use of colonoscopy and endoluminal ultrasonic biomicroscopy(eUBM)to track the progression of mouse colonic lesions.METHODS:Ten mice were treated with a single azoxy-methane intraperitoneal injection(week 1)followed by seven days of a dextran sulfate sodium treatment in their drinking water(week 2)to induce inflammationassociated colon tumors.eUBM was performed simultaneously with colonoscopy at weeks 13,17-20 and21.A 3.6-F diameter 40 MHz mini-probe catheter was used for eUBM imaging.The ultrasound mini-probe catheter was inserted into the accessory channel of a pediatric flexible bronchofiberscope,allowing simultaneous acquisition of colonoscopic and eUBM images.During image acquisition,the mice were anesthetized with isoflurane and kept in a supine position over a stainless steel heated surgical waterbed at 37℃.Both eUBM and colonoscopic images were captured and stored when a lesion was detected by colonoscopy or when the eUBM image revealed a modified colon wall anatomy.During the procedure,the colon was irrigated with water that was injected through a flush port on the mini-probe catheter and that acted as the ultrasound coupling medium between the transducer and the colon wall.Once the acquisition of the last eUBM/colonoscopy section for each animal was completed,the colons were fixed,paraffin-embedded,and stained with hematoxylin and eosin.Colon images acquired at the first time-point for each mouse were compared with subsequent eUBM/colonoscopic images of the same sites obtained in the following acquisitions to evaluate lesion progression.RESULTS:All 10 mice had eUBM and colonoscopic images acquired at week 13(the first time-point).Two animals died immediately after the first imaging acquisition and,consequently,only 8 mice were subjected to the second eUBM/colonoscopy imaging acquisition(at the second time-point).Due to the advanced stage of colonic tumorigenesis,5 animals died after the second time-point image acquisition,and thus,only three were subjected to the third eUBM/colonoscopy imaging acquisition(the third time-point).eUBM was able to detect the four layers in healthy segments of colon:the mucosa(the first hyperechoic layer moving away from the mini-probe axis),followed by the muscularis mucosae(hypoechoic),the submucosa(the second hyperechoic layer)and the muscularis externa(the second hypoechoic layer).Hypoechoic regions between the mucosa and the muscularis externa layers represented lymphoid infiltrates,as confirmed by the corresponding histological images.Pedunculated tumors were represented by hyperechoic masses in the mucosa layer.Among the lesions that decreased in size between the first and third time-points,one of the lesions changed from a mucosal hyperplasia with ulceration at the top to a mucosal hyperplasia with lymphoid infiltrate and,finally,to small signs of mucosal hyperplasia and lymphoid infiltrate.In this case,while lesion regression and modification were observable in the eUBM images,colonoscopy was only able to detect the lesion at the first and second time-points,without the capacity to demonstrate the presence of lymphoid infiltrate.Regarding the lesions that increased in size,one of them started as a small elevation in the mucosa layer and progressed to a pedunculated tumor.In this case,while eUBM imaging revealed the lesion at the first time-point,colonoscopy was only able to detect it at the second time-point.All colonic lesions(tumors,lymphoid infiltrate and mucosal thickening)were identified by eUBM,while colonoscopy identified just76%of them.Colonoscopy identified all of the colonic tumors but failed to diagnose lymphoid infiltrates and increased mucosal thickness and failed to differentiate lymphoid infiltrates from small adenomas.During the observation period,most of the lesions(approximately67%)increased in size,approximately 14%remained unchanged,and 19%regressed.CONCLUSION:Combining eUBM with colonoscopy improves the diagnosis and the follow-up of mouse colonic lesions,adding transmural assessment of the bowel wall. | Rossana C Soletti Kelly Z Alves Marcelo AP de Britto Dyanna G de Matos Mnica Soldan Helena L Borges Joo C Machado | 2013 | World Journal of Gastroenterology2013，19，44： | 1 |
| 5 | A geometric interpretation for transmission real losses minimization through the optimal power flow and its influence on voltage collapse显示文摘 | Alves D A Costa G R M | 2002 | Electric Power Systems Research2002，62，： | 1 |
| 6 | Mining user con- textual preferences 显示文摘 | DE AMO S BUENO M L P ALVES G | 2013 | Journal of InfmTnation & Data Manage- ment2013，4，1： | 1 |
| 7 | Mental health and physical inactivity during pregnancy:a cross-sectional study nested in the BRISA cohort study 显示文摘 | Takahasi E H Alves M T Alves G S | 2013 | Cad Sande Publica2013，29，8： | 1 |
| 8 | Fuel ethanol alter 25 years显示文摘 | Wheals A E Basso L C Alves D M G | 1999 | Trends Biotechnol1999，，17： | 1 |
| 9 | The demandcontrol model for job strain:a commentary on different ways to operationalize the exposure variable显示文摘 | ALVES M G BRAGA V M FAERSTEIN E | 2015 | Cad Saude Publica2015，31，1： | 1 |
| 10 | Friedel-Crafts acylaiton of anisole with acetic anhydride over silica-supported hetempolyphostungstic acid (HPW/SiO2 )显示文摘 | CARDOSO L A M ALVES W It GONZAGA A R E AGUIAR L M G ANDRADE H M C | 2004 | J Mol Catal A2004，209，12： | 1 |
| 11 | Higher education and employability of graduates: Will Bologna make a difference? 显示文摘 | Stiwne E E & Alves M G | 2010 | European Educational Research Journal2010，9，1： | 1 |
| 12 | Nanocomposites glass/conductive polymers显示文摘 | Zarbin A J G Paoli M D Alves O L | 1999 | Synth Met1999，99，3： | 1 |
| 13 | Early diagnostic and endoscopic dilatation for the treatment of acquired upper airway stenosis after intubation in children显示文摘 | MAKSOUD FILHO J G GONALVES M E CARDOSO S R | 2008 | J Pediatr Surg2008，43，7： | 1 |
| 14 | Multifractal characterization of saprolite particle-size distributions after topsoil removal 显示文摘 | Miranda J G V Montero E Alves M C | 2006 | Geoderma2006，134，： | 1 |
| 15 | Postharvestcontrol of brown rot and Rhizopus rot in plums and nectarines using carnaubawax显示文摘 | GON?ALVES F P MARTINS M C Jr SILVA G J | 2010 | Postharvest Biology and Technology2010，58，： | 1 |
| 16 | Electoral Surveys’Influence on the Voting Processes:A Cellular Automata Model显示文摘 | Alves S G Oliveira Neto N M Martins M L | 2002 | Physica A:Statistical Mechanics and Its Applications2002，316，14： | 1 |
| 17 | Nutritional quality and protein value of exotic almonds and nut from the Brazilian Savanna compared to peanut显示文摘 | De OLIVEIRA SOUSA A G FERNANDES D C ALVES A M | 2011 | Food Research International2011，44，： | 1 |
| 18 | Spatial activity and expression of plasma membrane H -ATPase in stem xylem of walnut during dormancy and growth resumption显示文摘 | ALVES G DEOURTEIX M FLEURAT-LESSARD P | 2007 | Tree Physiotogy2007，27，10： | 1 |
| 19 | Electoral surreysJ influ- ence on the voting processes: a cellular automata model显示文摘 | Alves S G Oliveira N M Martins M L | 2002 | PhysicaA2002，32，36： | 1 |
| 20 | Changes in motor subtype and risk for incident dementia in Parkinson's disease显示文摘 | Alves G Larsen J P Emre M | 2006 | Mov Disord2006，21，8： | 1 |
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