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| 1 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 2 | PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals显示文摘 | Maria Antonella Burza Carlo Pirazzi Cristina Maglio Kajsa Sj?holm Rosellina Margherita Mancina Per-Arne Svensson Peter Jacobson Martin Adiels Marco Giorgio Baroni Jan Borén Stefano Ginanni Corradini Tiziana Montalcini Lars Sj?str?m Lena Mariana Susann Car | 2012 | Digestive and Liver Disease2012，，12： | 2 |
| 3 | Increased cardiomyocyte apoptosis and changes in proapoptotic and antiapoptotic genes bax and Bcl-2 during left ventricular adaptations to chronic pressure overload in the rat显示文摘 | Gianluigi C Carmine M Giorgio S Antonella N Felicia F Giuseppe S | 1999 | Circulation1999，99，： | 1 |
| 4 | Short- Versus Long-Term Duration of Dual-Antiplatelet Therapy After Coronary Stenting: A Randomized Multicenter Trial显示文摘 | Marco Valgimigli Gianluca Campo Monia Monti Pascal Vranckx Gianfranco Percoco Carlo Tumscitz Fausto Castriota Federico Colombo Matteo Tebaldi Giuseppe Fucà Moh?d Kubbajeh Elisa Cangiano Monica Minarelli Antonella Scalone Caterina Cavazza Alice Frangione M | 2012 | Circulation2012，，16： | 1 |
| 5 | Traditional and Innovative Paths towards Time-based Competition显示文摘 | ALBERTO D T ANTONELLA M | 2000 | International Journal of Production Economics2000，66，3： | 1 |
| 6 | Lytic growth of HHV8:morphological aspects显示文摘 | Antonella T Paolo M Maria G A | 2000 | Ultrastruct Pathol2000，24，： | 1 |
| 7 | Glass fiber reinforced polymer pultruded members: constitutive model and stability analysis 显示文摘 | Antonella C Roberto D M | 2004 | Journal of Engineering Mechanics2004，130，8： | 1 |
| 8 | Local delivery of human tissue kallikrein gene accelerates spontaneous angiogenesis in mouse model of hindlimb ischemia显示文摘 | COSTANZA E ALESSANDRA M ANTONELLA Z | 2001 | Circulation2001，10，3： | 1 |
| 9 | A versatile and highly selective hypervalent iodine(III)/2,2,6,6-tetra-methyl-piperidinyloxyl-mediated oxidation of alcohols to carbonyl compounds显示文摘 | Roberto M Luca P | 1997 | J Org Chem1997，62，20： | 1 |
| 10 | Effect of propio- nyl-L-carnitine, L-arginine and nicotinic acid on the efficacy of var- denafil in the treatment of erectile dysfunction in diabetes 显示文摘 | Gentile V Antonini G Antonella Bertozzi M | 2009 | Curt Med Res Opin2009，25，9： | 1 |
| 11 | A novel ditopic zinc - salnphen maerocycle : a potential two - stationed wheel for - pseudorotaxanes显示文摘 | ANTONELLA D C LUIGI M CHIARA P | 2006 | Organic & Biomolecular Chemistry2006，4，24： | 1 |
| 12 | High concentmtions of prostate-specific antigen urine of women oral contraceptive显示文摘 | Ferdimand M Leone C Antonella C | 1998 | Clin Chem1998，44，1： | 1 |
| 13 | Outer product analysis of electronic nose and visible spectra: application to the measurement of peach fruit characteristics显示文摘 | Corrado DN Manuela ZS Antonella M | 2002 | Analytica Chimica Acta2002，45，1： | 1 |
| 14 | Aeromonas veronii biovar veronii septicaemia and acute suppurative cholangitis in a patient with hepatitis B显示文摘 | Antonella M Elio C Rosanna M | 2003 | J Med Microbiol2003，52，： | 1 |
| 15 | Outer product analysis o f electronic nose and visible spectra : application to the measurement of peach fruit characteristics显示文摘 | Corrado DN Manuela ZS Antonella M et 01 | 2002 | Analytica Chimica Acta2002，459，1： | 1 |
| 16 | Glass iiber reinforced polymer pultruded members : constitutive model and stability analysis 显示文摘 | Antonella C Roberto D M | 2004 | Journal of Engineering Mechanics2004，13，8： | 1 |
| 17 | Crystal structure of the blue multicoooer oxidase from the white-rot fungus Trametes trogii complexde with p-toluate显示文摘 | Iren M Antonella G Slivia T | 2008 | Inorganica Chimica Acta2008，361，14： | 1 |
| 18 | A novel ditopic zinc-salophen macrocycle:a potential two-stationed wheel for -pscudorotaxanes显示文摘 | Antonella D C Luigi M Chiara P | 2006 | Organic & Biomolecular Chemistry2006，4，24： | 1 |
| 19 | The novel proapoptotic activity of nonnatural enantiomer of Lentiginosine显示文摘 | Beatrice M Antonella M | 2010 | Glycobiology2010，20，5： | 1 |
| 20 | Evaluation of LIAISON treponema screen,A Novel recombinant antigen-based chemiluminescence immunoassay for laboratory diagnosis of syphilis显示文摘 | Antonella M Vittorio S Silvia A | 2005 | Clinical and Diagnostic Laboratory Immunology2005，12，10： | 1 |
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