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| 1 | Prostate cancer upgrading or downgrading of biopsy Gleason scores at radical prostatectomy:prediction of'regression to the mean'using routine clinical features with correlating biochemical relapse rates显示文摘Recommendations for managing clinically localized prostate cancer are structured around clinical risk criteria,with prostate biopsy(PB)Gleason score(GS)being the most important factor.Biopsy to radical prostatectomy(RP)specimen upgrading/downgrading is welldescribed,and is often the ratio nale for costly imaging or genomic studies.We prese nt simple,no-cost an a lyses of clinical parametersto predict which GS 6 and GS 8 patients will change to GS 7 at prostatectomy.From May 2006 to December 2012,1590 patientsunderwent robot-assisted radical prostatectomy(RARP).After exclusions,we identified a GS 6 cohort of 374 patients and a GS 8cohort of 91 patients.During this era,>1000 additional patients were enrolled in an active surveillanee(AS)program.For GS 6,265(70.9%)of 374 patients were upgraded,and the cohort included 183(48.9%)patients eligible for AS by the Prostate Cancer ResearchInternational Active Surveillance Study(PRIAS)standards,of which 57.9%were upgraded.PB features that predicted a>90%chanceof upgrading included≥7 cores positive,maximum foci length≥8 mm in any core,and total tumor involvement≥30%.For GS 8,downgrading occurred in 46(50.5%),which was significantly higher for single core versus multiple cores(80.4%vs 19.6%,P=0.011).Biochemical recurre nee(BCR)occurred in 3.4%of GS 6 upgraded versus 0%non upgraded,and in GS 8,19.6%downgraded versus42.2%nondown graded.In coun seling men with clin ically localized prostate can cer,the odds of GS cha nge should be presented,andcertain men with high-volume GS 6 or low-volume GS 8 can be counseled with GS 7-based recommendations. | Muammer Altok Patricia Troncoso Mary F Achim Surena F Matin Graciela N Gonzalez John W Davis | 2019 | Asian Journal of Andrology2019，21，6： | 4 |
| 2 | Numerical Simulation of Resin Infusion and Reinforcement Consolidation Under Flexible Cover 显示文摘 | Joubaud L Achim V Trochu F | 2005 | Polymer Composites2005，26，4： | 1 |
| 3 | Cmposition of ethanolic extracts of wood and bark from Acer saccharum and Betula alleghaniensis trees of different vigor classes显示文摘 | St-Pierre F Achim A Stevanovic T | | 0，，： | 1 |
| 4 | The influence of conditioning and regeneration on the separation behavior of rigid surface filters for the separation of particles from gases显示文摘 | Achim Dittler Heinz F Umhauer | 2001 | Powder Technology2001，120，： | 1 |
| 5 | Specific and sensitive quantification of folate vitamers in foods by stable isotope dilution assays using high performance liquid chromatography-tandem mas spectrometry 显示文摘 | Achim F Peter S Michael R | 2003 | Anal Bioanal Chem2003，，376： | 1 |
| 6 | Quantification of pantothenic acid and folates by stable isotope dilution assays显示文摘 | Michael R Achim F | 2002 | Journal of food comnosition and analysis2002，15，： | 1 |
| 7 | The influence of the precipitation/ageing temperature on a Cu/ZnO/ZrO2 catalyst for methanol synthesis from H2 and CO2显示文摘 | ELIAS F ACHIM S THILO L HARALD H INGO K | 2014 | ChemCatChem2014，6，6： | 1 |
| 8 | High resolution dendrometer measurements in a tropical mountain rainforest and a dry forest in South Ecudaor显示文摘 | Volland-Voigt F Achim B Ganzhi O | 2009 | TRACE Tree Rings in Ar chaeology Climatology and Ecology2009，7，： | 1 |
| 9 | Evaluating environmental risks of genetically modified crops- ecological harm criteria for regulatory decision-making显示文摘 | Olivier Sanvidoa JiJrg Romeisa Achim F athmannb | 2012 | Environ Sci Pol2012，15，1： | 1 |
| 10 | Advanced numerical simulation of liquid composite molding for process analysis and optimization 显示文摘 | Trochu F Ruiz E Achim V | 2006 | Composites : Part A2006，37，： | 1 |
| 11 | Evidence for a warm-humid climate in arid northwestern China during 40 - 30 ka BP 显示文摘 | Yang B Shi Y F Achim B | 2004 | Quaternary Science Reviews2004，26，6： | 1 |
| 12 | Numerical Simulation of Resin Infusion and Reinforcement Consolidation Under Flexible Cover显示文摘 | Joubaud L Achim V Trcchu F | 2005 | Polymer Composites2005，26，4： | 1 |
| 13 | Micro- bial production of single cell from deproteinized whey concentrates 显示文摘 | Nadja Schultz Chang L F Achim Hauck | 2005 | Appl Microbiol Biotechnol2005，，10： | 1 |
| 14 | Human hibernating myoeardium is jeopardized by apoptotie and autophagie cell death显示文摘 | ALBRECHT E ACHIM M V HOLGER N E F | 2004 | J Am Coll Cardiol2004，43，： | 1 |
| 15 | A novel system for robust lane detection and tracking显示文摘 | WANG Y F NAIM D ACHIM A | 2012 | Signal Processing2012，92，2： | 1 |
| 16 | Carboxylation of phenylphosphate by phenol carboxylase,an enzyme system of anerobic phenol metabolism显示文摘 | Achim L Georg F | 1992 | J Bacteriol1992，174，11： | 1 |
| 17 | A novel system for robust lane detection and tracking显示文摘 | WANG Y F DAHNOUN N ACHIM A | 2012 | Signal Pro-cessing2012，，： | 1 |
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