|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Molecular detection of monocyte chemotactic protein-1 polymorphism in spontaneous bacterial peritonitis patients显示文摘AIM: To investigate the association of the functional monocyte chemotactic protein-1(MCP-1) promoter polymorphism(A-2518G) with spontaneous bacterial peritonitis(SBP).METHODS: Fifty patients with post-hepatitis C liver cirrhosis and ascites were categorized into two groups; group Ⅰ included 25 patients with SBP and group Ⅱ included 25 patients free from SBP. In addition, a group of 20 healthy volunteers were included. We assessed the MCP-1 gene polymorphism and gene expression as well as interleukin(IL)-10 levels in both blood and ascitic fluid. RESULTS: A significant MCP-1 gene polymorphism was detected in groups Ⅰ and Ⅱ(P = 0.001 and 0.02 respectively). Group Ⅰ was associated with a significantly higher frequency of AG genotype [control 8(40%) vs SBP 19(76.0%), P < 0.001], and group Ⅱ was associated with a significantly higher frequency of GG genotype when compared to healthy volunteers [control 1(5%) vs cirrhotic 16(64%), P < 0.001]. Accordingly, the frequency of G allele was significantly higher in both groups(Ⅰ and Ⅱ) [control 10(25%) vs SBP 27(54%), P < 0.001 and vs cirrhotic 37(74.0%), P < 0.001, respectively]. The total blood and ascetic fluid levels of IL-10 and MCP-1 gene expression were significantly higher in group Ⅰ than in group Ⅱ. Group Ⅰ showed significant reductions in the levels of MCP-1 gene expression and IL-10 in the whole blood and ascetic fluid after therapy. CONCLUSION: MCP-1 GG genotype and G allele may predispose HCV infected patients to a more progressive disease course, while AG genotype may increase the susceptibility to SBP. Patients carrying these genotypes should be under supervision to prevent or restrict further complications. | Maysa Kamal Salama Dina Sabry Mohamed AS Al-Ghussein Rasha Ahmed Sayed AbdAllah Fatma Mohamed Taha Wael Fathy Miriam Safwat Wadie Mona Nabih Amr Abul-Fotouh Tarneem Darwish | 2014 | World Journal of Gastroenterology2014，20，33： | 7 |
| 2 | Ab external scleral fixation of the Cionni modified capsular tension ring显示文摘 | Ahmed Ⅱ K Crandall AS | 2001 | J Cataract Refract Surg2001，27，： | 1 |
| 3 | The occipital artery for posterior circulation bypass:microsurgical anatomy显示文摘 | AteO Ahmed AS Niemann D | 2008 | Neurosurg Focus2008，24，2： | 1 |
| 4 | Nonpenetrating glaucoma sur- gery 显示文摘 | Goldsmith JA Ahmed IK Crandall AS | 2005 | Ophthcdmol Clin North Am2005，18，3： | 1 |
| 5 | Small-incision iris fixation of foldable intraocular lenses in the absence of capsule support 显示文摘 | C-ondon GP Masket S i Kranemann C Crandall AS Ahmed Ⅱ | 2007 | Ophthalmology2007，114，7： | 1 |
| 6 | Neurodevelop -mental se- quelae in pneumococcal meningitis cases in Bangladesh:a compre- hensive follow - up study 显示文摘 | Saha SK Khan NZ Ahmed AS | 2009 | Clinical Infectious Diseases2009，48，2： | 1 |
| 7 | Antimicrobial activity and brine shrimp lethality bioassay of the leaves extract of Dillenia indica linn显示文摘 | Apu AS Muhit MS Tareq SM Pathan AH Jamaluddin ATM Ahmed M | 2010 | J Young Pharm2010，2，1： | 1 |
| 8 | Hepatie dys- function in kidney transplant recipients: prevalence and impact on graft and patient survival显示文摘 | Osama AG Mohamed AS Ahmed AH | 2007 | Clinical and Experimental Nephrology2007，11，4： | 1 |
| 9 | Matrix metalloprotein- ases and their pathological upregulation in multiple sclerosis : an o- verview 显示文摘 | Javaid MA Abdallah MN Ahmed AS | 2013 | Acta Neurol Belg2013，113，4： | 1 |
| 10 | Preoper- ative peritonsillar infiltration of dexamethasone and levobupivacaine reduces 显示文摘 | Basuni AS Ahmed Ezz HA Albirmawy OA | 2013 | J Anesth2013，27，： | 1 |
| 11 | The occipital artery for posterior circulation bypass: microsurgical anatomy 显示文摘 | Ates O Ahmed AS Niemann D | 2008 | Neurosurg Focus2008，24，2： | 1 |
| 12 | The effect of metformin on bloodglucose control in overweight patients with type 1 diabetes显示文摘 | Khan AS McLoughney CR Ahmed AB | 2006 | Diabet Med2006，23，10： | 1 |
| 13 | Functional andmorphological effects of postpercutaneous nephrolithotomysuperselective renal angiographic embolization 显示文摘 | AhmedRE Ahmed AS Tarek M | 2008 | Urol2008，71，3： | 1 |
| 14 | Chewing gum in preventing postoperative ileus in women undergoing caesarean section: a systematic review and meta-analysis of randomised controlled trials显示文摘 | Craciunas L Sajid MS Ahmed AS | 2014 | BJOG2014，121，7： | 1 |
| 15 | Septicemic neonates without umbar puncture: What are we missing显示文摘 | Hoque MM Ahmed AS Chowdhury MA | 2006 | J Trop Pediatr2006，52，1： | 1 |
| 16 | Functional and mor-phol ogical effects of postpercutaneous nephrolithotomy superseleetive renal angiographic embolization 显示文摘 | Ahmed RE Ahmed AS Tarek M | 2008 | Urol2008，71，3： | 1 |
| 17 | Use of self expanding stents in distal small cerebral vessels显示文摘 | Turk AS Niemann DB Ahmed M Aagaard--Kienitz B | 2007 | AJNR Am J Neuroradiol2007，28，： | 1 |
| 18 | Septicemic neonates without lumbar puncture:What are we missing显示文摘 | Hoque MM Ahmed AS Chowdhury MA | 2006 | J Trop Pediatr2006，52，1： | 1 |
| 19 | Effect of skin barrier therapy on neonatal mortality rates in preterm infants in Bangladesh: a randomized, controlled, clinical trial 显示文摘 | Darmstadt GL Saha SK Ahmed AS | 2008 | Pediatrics2008，121，3： | 1 |
| 20 | Microstrnctural and compositional characterisation of the pyrocarbon interlayer in SiC coated low density carbon/carbon composites显示文摘 | Ahmed AS Rawlings RD | 2011 | Journal of the European Ceramic Society2011，31，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员