|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Replacement of retinyl esters by polyunsaturated triacylglycerol species in lipid droplets of HSCs during activation显示文摘 | Testerink N Ajat M Houweling M | | 0，，： | 1 |
| 2 | Socioeconomic di{{erentials in the temperature mortality relationship in Sao Paulo, Brazil显示文摘 | Gouveia N H ajat S Armstrong B | 2003 | Internati- anal Journal o{ Epidemiology2003，32，： | 1 |
| 3 | Replacement of retinyl esters by polyunsaturated triacylglycerol species in lipid droplets of hepatic stellate cells during activation显示文摘 | Testerink N Ajat M Houweling M | | 0，，： | 1 |
| 4 | Using hybrid models to predict blood pressure reactivity to unsupported back based on anthropometric characteristics显示文摘目的:准确测量血压(BP)对于流行病学研究、筛查规划、调研研究和高血压相关病变(冠心病、中风、肾衰竭等)的早期诊断及预防有重要意义。被测者体位对于准确测量血压有重要影响。血压测量指南建议测试时被测者应在后背有支撑的情况下保持坐姿,以避免血压读数偏高。本文使用混杂模型预测血压对于无支撑后背的反应。创新点:本文考虑血压正常和高血压测试者的人体预测变量(如年龄、身高、体重、体块指数和上臂周长(AC)),使用基于PCA的前向逐步回归(PCA-SWR)、基于PCA的人工神经网络(PCA-ANN)、基于PCA的自适应神经模糊推理系统(PCA-ANFIS)和基于PCA的最小方差支持向量机(PCA-LS-SVM)等模型预测血压对无支撑后背的反应。方法:使用PCA消除人体预测变量间的多重共线性,并在原始数据集中选取主元(PC)。所选主元被输入至所建立预测模型用于建模及测试。结论:通过评估合适的统计指标(确定性系数、平均平方根误差、平均绝对百分比误差),得出较之其他模型,PCA-LS-SVM对于预测血压反应较有前景。此评估也展示了混杂模型在预测生物医学领域其他参数时的重要性和先进性。 | Gurmanik KAUR Ajat Shatru ARORA Vijender Kumar JAIN | 2015 | Frontiers of Information Technology & Electronic Engineering2015，16，6： | 1 |
| 5 | Generation of high energy laser-driven electron and proton sources with the 200 TW system VEGA 2 at the Centro de Laseres Pulsados显示文摘The Centro de Laseres Pulsados in Salamanca,Spain has recently started operation phase and the first user access period on the 6 J 30 fs 200 TW system(VEGA 2)already started at the beginning of 2018.In this paper we report on two commissioning experiments recently performed on the VEGA 2 system in preparation for the user campaign.VEGA 2 system has been tested in different configurations depending on the focusing optics and targets used.One configuration(long focal length F=130 cm)is for underdense laser-matter interaction where VEGA 2 is focused onto a low density gas-jet generating electron beams(via laser wake field acceleration mechanism)with maximum energy up to 500 MeV and an X-ray betatron source with a 10 keV critical energy.A second configuration(short focal length F= 40 cm)is for overdense laser-matter interaction where VEGA 2 is focused onto a 5 μm thick Al target generating a proton beam with a maximum energy of 10 MeV and temperature of 2.5 MeV.In this paper we present preliminary experimental results. | L.Volpe R.Fedosejevs G.Gatti J.A.Pérez-Hernández C.Méndez J.Apinaniz X.Vaisseau C.Salgado M.Huault S.Malko G.Zeraouli V.Ospina A.Longman D.De Luis K.Li O.Varela E.García I.Hernandez J.D.Pisonero J.Garcia Ajates J.M.Alvarez C.García M.Rico D.Arana J.Hernandez-Toro L.Roso | 2019 | High Power Laser Science and Engineering2019，7，2： | 0 |
| 6 | Multi-gigahertz mode-locked femtosecond Yb:KLuW waveguide lasers显示文摘We demonstrate multi-gigahertz continuous-wave mode-locking of a Yb:KLuW waveguide laser. A femtosecondlaser-inscribed Yb:KLuW channel waveguide in an extended laser cavity delivers a fundamentally mode-locked laser near 1030 nm. A tunable few-centimeter-long cavity containing a single-walled carbon nanotube saturable absorber as mode-locker generates self-starting femtosecond pulses with average output powers exceeding210 mW at repetition rates of 2.27, 2.69, and 3.55 GHz. The laser cavity, which includes a wedged waveguide,is extended by using a lens pair that controls the laser fluence on the saturable absorber for reliable mode-locked operation without instability. The presented laser performance, mode-locked up to 3.55 GHz, highly suggests the potential of crystalline Yb:KLuW waveguides for realizing high-power ultrafast lasers with higher GHz repetition rates in a quasi-monolithic cavity. | JI EUN BAE XAVIER MATEOS MAGDALENA AGUILÓ FRANCESC DÍAZ JAVIER GARCÍA AJATES CAROLINA ROMERO JAVIER RODRÍGUEZ VÁZQUEZ DE ALDANA FABIAN ROTERMUND | 2022 | Photonics Research2022，10，11： | 0 |
| 7 | Antimicrobial activity and mode of action of terpene linalyl anthranilate against carbapenemase-producing Klebsiella pneumoniae显示文摘Mining of plant-derived antimicrobials is the major focus at current to counter antibiotic resistance. This study was conducted to characterize the antimicrobial activity and mode of action of linalyl anthranilate(LNA) against carbapenemase-producing Klebsiella pneumoniae(KPC-KP). LNA alone exhibited bactericidal activity at 2.5%(V/V), and in combination with meropenem(MPM) at 1.25%(V/V). Comparative proteomic analysis showed a significant reduction in the number of cytoplasmic and membrane proteins,indicating membrane damage in LNA-treated KPC-KP cells. Up-regulation of oxidative stress regulator proteins and down-regulation of oxidative stress-sensitive proteins indicated oxidative stress. Zeta potential measurement and outer membrane permeability assay revealed that LNA increases both bacterial surface charge and membrane permeability. Ethidium bromide influx/efflux assay showed increased uptake of ethidium bromide in LNA-treated cells, inferring membrane damage. Furthermore, intracellular leakage of nucleic acid and proteins was detected upon LNA treatment. Scanning and transmission electron microscopies again revealed the breakage of bacterial membrane and loss of intracellular materials. LNA was found to induce oxidative stress by generating reactive oxygen species(ROS) that initiate lipid peroxidation and damage the bacterial membrane. In conclusion, LNA generates ROS, initiates lipid peroxidation, and damages the bacterial membrane, resulting in intracellular leakage and eventually killing the KPC-KP cells. | Shun-Kai Yang Khatijah Yusoff Mokrish Ajat Wai-Sum Yap Swee-Hua Erin Lim Kok-Song Lai | 2021 | Journal of Pharmaceutical Analysis2021，11，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员