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| 1 | Stem cell therapy for chronic skin wounds in the era of personalized medicine:From bench to bedside显示文摘With the significant financial burden of chronic cutaneous wounds on the healthcare system,not to the personal burden mention on those individuals afflicted,it has become increasingly essential to improve our clinical treatments.This requires the translation of the most recent benchtop approaches to clinical wound repair as our current treatment modalities have proven insufficient.The most promising potential treatment options rely on stem cellbased therapies.Stem cell proliferation and signaling play crucial roles in every phase of the wound healing process and chronic wounds are often associated with impaired stem cell function.Clinical approaches involving stem cells could thus be utilized in some cases to improve a body’s inhibited healing capacity.We aim to present the laboratory research behind the mechanisms and effects of this technology as well as current clinical trials which showcase their therapeutic potential.Given the current problems and complications presented by chronic wounds,we hope to show that developing the clinical applications of stem cell therapies is the rational next step in improving wound care. | Elam Coalson Elliot Bishop Wei Liu Yixiao Feng Mia Spezia Bo Liu Yi Shen Di Wu Scott Du Alexander J.Li Zhenyu Ye Ling Zhao Daigui Cao Alissa Li Ofir Hagag Alison Deng Winny Liu Mingyang Li Rex C.Haydon Lewis Shi Aravind Athiviraham Michael J.Lee Jennifer Moriatis Wolf Guillermo A.Ameer Tong-Chuan He Russell R.Reid | 2019 | Genes & Diseases2019，6，4： | 6 |
| 2 | Progress of Jinping Underground laboratory for Nuclear Astrophysics(JUNA)显示文摘Jinping Underground laboratory for Nuclear Astrophysics(JUNA) will take the advantage of the ultra-low background of CJPL lab and high current accelerator based on an ECR source and a highly sensitive detector to directly study for the first time a number of crucial reactions occurring at their relevant stellar energies during the evolution of hydrostatic stars. In its first phase, JUNA aims at the direct measurements of^(25)Mg(p,γ)^(26)Al,^(19)F(p,α)^(16)O,^(13)C(α,n)^(16)O and ^(12)C(α,γ)^(16)O reactions. The experimental setup,which includes an accelerator system with high stability and high intensity, a detector system, and a shielding material with low background, will be established during the above research. The current progress of JUNA will be given. | WeiPing Liu ZhiHong Li JiangJun He XiaoDong Tang Gang Lian Zhu An JianJun Chang Han Chen QingHao Chen XiongJun Chen ZhiJun Chen BaoQun Cui XianChao Du ChangBo Fu Lin Gan Bing Guo GuoZhu He Alexander Heger SuQing Hou HanXiong Huang Ning Huang BaoLu Jia LiYang Jiang Shigeru Kubono JianMin Li KuoAng Li Tao Li YunJu Li Maria Lugaro XiaoBing Luo HongYi Ma ShaoBo Ma DongMing Mei YongZhong Qian JiuChang Qin Jie Ren YangPing Shen Jun Su LiangTing Sun WanPeng Tan Isao Tanihata Shuo Wang Peng Wang YouBao Wang Qi Wu ShiWei Xu ShengQuan Yan LiTao Yang Yao Yang XiangQing Yu Qian Yue Sheng Zeng HuanYu Zhang Hui Zhang LiYong Zhang NingTao Zhang QiWei Zhang Tao Zhang XiaoPeng Zhang XueZhen Zhang ZiMing Zhang Wei Zhao Zuo Zhao Chao Zhou | 2016 | Science China(Physics,Mechanics & Astronomy)2016，59，4： | 3 |
| 3 | Photonic synapses with ultralow energy consumption for artificial visual perception and brain storage显示文摘The human visual system,dependent on retinal cells,can be regarded as a complex combination of optical system and nervous system.Artificial retinal system could mimic the sensing and processing function of human eyes.Optically stimulated synaptic devices could serve as the building blocks for artificial retinas and subsequent information transmission system to brain.Herein,photonic synaptic transistors based on polycrystalline MoS_(2),which could simulate human visual perception and brain storage,are presented.Moreover,the photodetection range from visible light to near-infrared light of MoS_(2) multilayer could extend human eyes’vision limitation to near-infrared light.Additionally,the photonic synaptic transistor shows an ultrafast speed within 5μs and ultralow power consumption under optical stimuli about 40 aJ,several orders of magnitude lower than biological synapses(50 ms and 10 fJ).Furthermore,the backgate control could act as emotional modulation of the artificial brain to enhance or suppress memory function,i.e.the intensity of photoresponse.The proposed carrier trapping/detrapping as the main working mechanism is presented for the device.In addition,synaptic functionalities including short synaptic plasticity,long synaptic plasticity and paired-pulse facilitation could be successfully simulated based on the prepared device.Furthermore,the large difference between short synaptic plasticity and long synaptic plasticity reveals the better image pre-processing function of the prepared photonic synapses.The classical Pavlovian conditioning associated with the associative learning is successfully implemented as well.Therefore,the efficient and rich functionalities demonstrate the potential of the MoS_(2) synaptic device that integrates sensing-memory-preprocessing capabilities for realizing artificial neural networks with different emotions that mimic human retina and brain. | Caihong Li Wen Du Yixuan Huang Jihua Zou Lingzhi Luo Song Sun Alexander OGovorov Jiang Wu Hongxing Xu Zhiming Wang | 2022 | Opto-Electronic Advances2022，5，9： | 3 |
| 4 | Biomaterials as carrier, barrier and reactor for cell-based regenerative medicine显示文摘房间治疗在过去的几十年在再生药获得了巨大的成功。然而,质问例如房间损失,死亡并且在移植以后有免疫力拒绝仍然坚持。Biomaterials 作为搬运人被设计了为本地织物新生把房间送到理想的区域;当保护的障碍从宿主免疫者攻击移植了细胞;或当刺激的反应堆招待房间招募, homing 和区别。与 biomaterials 的帮助,在治疗效率的改进与平淡的免费基于房间的治疗相比在退化疾病的众多的动物模型被表明了。帮助房间治疗推进的 biomaterial 的新兴的临床的应用为复杂疾病在再生治疗甚至痊愈加亮他们的大诺言,它被没有通过由常规治疗学的途径认识到。 | Chunxiao Qi Xiaojun Yan Chenyu Huang Alexander Melerzanov Yanan Du | 2015 | Protein & Cell2015，6，9： | 2 |
| 5 | Topotecan versus treosulfan, an alkylating agent, in patients with epithelial ovarian cancer and relapse within 12 months following 1st-line platinum/paclitaxel chemotherapy显示文摘 | Werner Meier Andreas du Bois Alexander Reuss | 2009 | 2(114):199-2052009，2，114： | 1 |
| 6 | A site study of durability indexes for concrete in marine conditions显示文摘 | DU PREEZ A A ALEXANDER M G | 2004 | Materials and Structures2004，，37： | 1 |
| 7 | Interrelationships between sirtuin 1 and transcription factors p53 and NF-κB (p50/p65) in the control of ovarian cell apoptosis and proliferation显示文摘 | Alexander V. Sirotkin Petra Dekanová Abdel Halim Harrath Saleh Hamad Alwasel Du?an Va?í?ek | 2014 | Cell and Tissue Research2014，，2： | 1 |
| 8 | A role for natural simian immunodeficiency virus and human immunodeficiency virus type 1 nef alleles in lymphocyte activation 显示文摘 | ALEXANDER L DU Z ROSENZWEIG M | 1997 | J Virol1997，71，8： | 1 |
| 9 | CO 2 emissions embodied in China–US trade: Input–output analysis based on the emergy/dollar ratio显示文摘 | Huibin Du Jianghong Guo Guozhu Mao Alexander M. Smith Xuxu Wang Yuan Wang | 2011 | Energy Policy2011，，10： | 1 |
| 10 | A comparative study of SOAP and DCOM显示文摘 | Alexander Davis Du Zhang | 2005 | The Journal of Systems and Software2005，76，： | 1 |
| 11 | The potential contribution of ecotourism to African wild dog Lycan pictus conservation in South Africa显示文摘 | Lindsey P A Alexander R R Du Toit J T | 2005 | Biological Conservation2005，123，： | 1 |
| 12 | The potential contribution of ecotourism to African wild dog Lycaon pictus conservation in South Africa显示文摘 | Lindsey P A Alexander R R Du Toit J T | 2005 | Biological Conservation2005，123，3： | 1 |
| 13 | Film formation and redispersion of waterborne latex coatings 显示文摘 | ALEXANDER DU CHESNE ALBENA BOJKOVA JACEK GAPINSKI | 2000 | Journal of Colloid and Interface Scienee2000，224，1： | 1 |
| 14 | Carboplatin Hypersensitivity: Does Introduction of Skin Test and Desensitization Reliably Predict and Avoid the Problem? A Prospective Single-Center Study显示文摘 | Ruth Gomez Philipp Harter Hans-Joachim Lück Alexander Traut Stefan Kommoss Michaela Kandel Andreas du Bois | 2009 | International Journal of Gynecological Cancer2009，，7： | 1 |
| 15 | CO 2 emissions embodied in China–US trade: Input–output analysis based on the emergy/dollar ratio显示文摘 | Huibin Du Jianghong Guo Guozhu Mao Alexander M. Smith Xuxu Wang Yuan Wang | 2011 | Energy Policy2011，，10： | 1 |
| 16 | Uncertainty in Multiple Penetration Depth Fringing Electric Field Sensor Measurements 显示文摘 | Alexander Mamishev Yanqing Du Markus Zahn | 2002 | Instrumentation and Measurement IEEE Transactions on2002，51，6： | 1 |
| 17 | A site study of durability indexes for concrete in marine conditions显示文摘 | DU PREEZ A A ALEXANDER M G | 2004 | Materials and Structures2004，37，267： | 1 |
| 18 | The murine gastrin promoter is synergistically activated by transforming growth factor-/smad and wnt signaling pathways显示文摘 | Lei S Alexander DU Abhijit CH Lindsay WO Timothy CW | 2004 | J Biol Chem2004，279，42： | 1 |
| 19 | The segregation of suffactant upon film formation of latex dispersions:an investigation by energy filtering transmission electron microscopy显示文摘 | ALEXANDER DU CHESNE BETTINA GERHARZ GUNTER LIES- ER | 1997 | Polymer International1997，，43： | 1 |
| 20 | Prognostic factors for complete debulking in advanced ovarian cancer and its impact on survival. An exploratory analysis of a prospectively randomized phase III study of the Arbeitsgemeinschaft Gynaekologische Onkologie Ovarian Cancer Study Group (AGO-OVA显示文摘 | Pauline Wimberger Nils Lehmann Rainer Kimmig Alexander Burges Werner Meier Andreas Du Bois | 2007 | Gynecologic Oncology2007，，1： | 1 |
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