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| 1 | Intermittent fasting promotes adipose thermogenesis and metabolic homeostasis via VEGF-mediated alternative activation of macrophage显示文摘 | Kyoung-Han Kim Yun Hye Kim Joe Eun Son Ju Hee Lee Sarah Kim Min Seon Choe Joon Ho Moon Jian Zhong Kiya Fu Florine Lenglin Jeong-Ah Yoo Philip J Bilan Amira Klip Andras Nagy Jae-Ryong Kim Jin Gyoon Park Samer MI Hussein Kyung-Oh Doh Chi-chung Hui Hoon-Ki Sung | 2017 | Cell Research2017，27，11： | 9 |
| 2 | Light Triggers the miRNA-Biogenetic Inconsistency for De-etiolated Seedling Survivability in Arabidopsis thaliana显示文摘The shift of dark-grown seedlings into light causes enormous transcriptome changes followed by a dramatic developmental transition.Here,we show that microRNA(miRNA)biogenesis also undergoes regulatory changes during de-etiolation.Etiolated seedlings maintain low levels of primary miRNAs(pri-miRNAs)and miRNA processing core proteins,such as Dicer-like 1,SERRATE,and HYPONASTIC LEAVES 1,whereas during de-etiolation both pri-miRNAs and the processing components accumulate to high levels.However,the levels of most miRNAs do not notably increase in response to light.To reconcile this inconsistency,we demonstrated that an unknown suppressor decreases miRNA-processing activity and light-induced SMALL RNA DEGRADING NUCLEASE 1 shortens the half-life of several miRNAs in de-etiolated seedlings.Taken together,these data suggest a novel mechanism,miRNA-biogenetic inconsistency,which accounts for the intricacy of miRNA biogenesis during de-etiolation.This mechanism is essential for the survival of de-etiolated seedlings after long-term skotomorphogenesis and their optimal adaptation to ever-changing light conditions. | Suk Won Choi Moon Young Ryu Andras Viczian Hyun Ju Jung Gu Min Kim Agustin LArce Natalia PAchkar Pablo Manavella Ulla Dolde Stephan Wenke Attila Molnar Ferenc Nagy Seok Keun Cho Seong Wook Yang | 2020 | Molecular Plant2020，13，3： | 3 |
| 3 | Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming显示文摘 | Payman Samavarchi-Tehrani Azadeh Golipour Laurent David Hoon-ki Sung Tobias A. Beyer Alessandro Datti Knut Woltjen Andras Nagy Jeffrey L. Wrana | 2010 | Cell Stem Cell2010，，1： | 3 |
| 4 | Analysis of optic disc damage by optical coherence tomography in terms of therapy in non-arteritic anterior ischemic optic neuropathy显示文摘This study aimed to assess the relationship between the rate of nerve fiber loss in non-arteritic anterior ischemic optic neuropathy(NAION) and time delay before therapy.Total 24 patients received the same treatment within or after 2wk(early and late groups).There were significantly lower level of destruction of nerve fibers(P=0.0014) and significantly better visual field sensitivity(P=0.039) in early group.The results indicate that therapy should be started within 2wk.The degree of ischemic damage due to NAION correlates well with retinal nerve fiber layer thickness and the ischemia-induced decrease in visual field sensitivity. | Zsuzsa Balogh Marta Kasza Julianna Varadai Izabella Reznek Judit Damjanovich Adrienne Csutak Andras Berta Valeria Nagy | 2016 | International Journal of Ophthalmology(English edition)2016，9，9： | 2 |
| 5 | A Short Amino-Terminal Part of Arabidopsis Phytochrome A Induces Constitutive Photomorphogenic Response显示文摘Phytochrome A (phyA ) 是在 Arabidopsis thaliana 察觉到的 far-red 光的主导的光敏电阻器。phyA 在发信号的变白的幼苗,和导致光的 phyA 的细胞质在高水平积累被一个复杂规章的网络调停。这包括光 -- 并且进在 vivo 的原子核的本国的 phyA 的 FHY1/FHL 蛋白质依赖者 translocation。phyA (PHYA406 ) 的短 N 终端碎片对 phenocopy 足够,这也被显示出在 vitro 的这个高度调整的细胞的过程。为了测试这 N 终端的生物活动,在 planta phyA 碎裂,我们生产了表示 PHYA406YFP 的转基因的 phyA-201 植物(黄荧光灯蛋白质) DD, PHYA406YFPDDNLS (原子本地化信号) ,和 PHYA406YFPDDNES (原子出口信号) 熔化蛋白质。这里,我们报导 PHYA406YFPDD 被进口进原子核,而 PHYA406YFPDDNLS 和 PHYA406YFPDDNES 显示期望的组成的本地化模式,这进程部分是轻依赖者的。我们的结果证明这些截断的 phyA 蛋白质是轻马厩的,当局部性时,他们在他们的原子核,和两个都不触发组成的象 photomorphogenic 一样回答导致合适的 phyA 发信号。我们证明在 vitro 并且在 vivo PHYA406, Pfr 和 Pr 绑 COP1, photomorphogenesis 的一个一般抑压者,并且在原子身体与它共同本地化。因此,我们断定在 planta,截断的 PHYA406 蛋白质以一种光无关的方式在原子核使 COP1 失去活性。 | Andra's Viczia'n E'va Ada'm Iris Wolf Ja'nos Bindics Stefan Kircher Marc Heijde Roman Ulm Eberhard Scha'fer Ferenc Nagy | 2012 | Molecular Plant2012，5，3： | 2 |
| 6 | Inflammation and oxidative stress caused might lead to left ventricular diastolic and hypertension by nitric oxide synthase uncoupling systolic dysfunction in patients with显示文摘 | Zsuzsanna Szelenyi Adam Fazakas Gabor Szenasi Melinda KiSS Narcis Tegze Bertalan CsabaFekete Eszter Nagy Imre Bodo Balint Nagy Attila Molvarec Attila Patocs Lilla Pepo Zoltan Prohatszka Andras Vereckei | 2015 | Journal of Geriatric Cardiology2015，12，1： | 2 |
| 7 | Combining algorithms for automatic detection of optic disc and macula in fundus images显示文摘 | Rashid Jalal Qureshi Laszlo Kovacs Balazs Harangi Brigitta Nagy Tunde Peto Andras Hajdu | 2011 | Computer Vision and Image Understanding2011，，1： | 1 |
| 8 | Micro RNA profile before and after antiviral therapy in liver transplant recipients for hepatitis C virus cirrhosis显示文摘 | Fanni Gelley Gergely Zadori Balazs Nemes Matteo Fassan Gabor Lendvai Eniko Sarvary Attila Doros Zsuzsanna Gerlei Peter Nagy Zsuzsa Schaff Andras Kiss | 2014 | J Gastroenterol Hepatol2014，，1： | 1 |
| 9 | Characterization of packed beds of plant materials processed by supercritical fluid extraction显示文摘 | Nagy B Simandi B Andras C D | 2008 | Journal of Food Engineering2008，88，1： | 1 |
| 10 | Progress made in the reprogramming field: new factors, new strategies and a new outlook显示文摘 | Samer MI Hussein Andras A Nagy | 2012 | Current Opinion in Genetics & Development2012，，5： | 1 |
| 11 | Ras pathway inhibition prevents neovascularization by repressing endothelial cell sprouting显示文摘 | Westenskow Peter D Kurihara Toshihide Aguilar Edith Scheppke Elizabeth L Moreno Stacey K Wittgrove Carli Marchetti Valentina Michael Iacovos P Anand Sudarshan Nagy Andras Cheresh David Friedlander Martin | 2013 | Journal of Clinical Investigation2013，，11： | 1 |
| 12 | Derivation of completely cell culture-derived mice from early-passage embryonic stem cells显示文摘 | | 1993 | Proc Natl Acad Sci USA1993，90，： | 1 |
| 13 | Trombophilic screening for nonarteritic anterior ischemic optic neuropathy显示文摘 | Valeria Nagy Zita Steiber Lili Takacs Gyorgy Vereb Andras Berta Zsuzsanna Bereczky Gyorgy Pfliegler | 2006 | Graefe’s Archive for Clinical and Experimental Ophthalmology2006，，1： | 1 |
| 14 | Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming显示文摘 | Payman Samavarchi-Tehrani Azadeh Golipour Laurent David Hoon-ki Sung Tobias A. Beyer Alessandro Datti Knut Woltjen Andras Nagy Jeffrey L. Wrana | 2010 | Cell Stem Cell2010，，1： | 1 |
| 15 | The color of mice: in the light of GFP-variant reporters显示文摘 | Anna-Katerina Hadjantonakis Andras Nagy | 2001 | Histochemistry and Cell Biology2001，，1： | 1 |
| 16 | Manipulating the mouse embryo:a laboratory manual (third edition 影印版)显示文摘 | Andras Nagy Marina Gertsenstein Kristina Vintersten | 2004 | 北京:科学出版社2004，，： | 1 |
| 17 | Mechanisms of vascularization in murine models of primary and metastatic tumor growth显示文摘Directed capillary ingrowth has long been considered synonymous with tumor vascularization.However,the vasculature of primary tumors and metastases is not necessarily formed by endothelial cell sprouting;instead,malignant tumors can acquire blood vessels via alternative vascularization mechanisms,such as intussusceptive microvascular growth,vessel co-option,and glomeruloid angiogenesis.Importantly,in response to anti-angiogenic therapies,malignant tumors can switch from one vascularization mechanism to another.In this article,we briefly review the biological features of these mechanisms and discuss on their significance in medical oncology. | Edina Bugyik Ferenc Renyi-Vamos Vanessza Szabo Katalin Dezso Nora Ecker Andras Rokusz Peter Nagy Balazs Dome Sandor Paku | 2016 | Chinese Journal of Cancer2016，35，2： | 1 |
| 18 | Autocrine VEGF Signaling Is Required for Vascular Homeostasis显示文摘 | Sunyoung Lee Tom T. Chen Chad L. Barber Maria C. Jordan Jared Murdock Sharina Desai Napoleone Ferrara Andras Nagy Kenneth P. Roos M. Luisa Iruela-Arispe | 2007 | Cell2007，，4： | 1 |
| 19 | Effect of silver-nanoparticles generated in poly(vinyl alcohol)membranes on ethanol dehydration via pervaporation显示文摘Pervaporation is an important membrane separation method of chemical engineering.In this work,silver-nanoparticles-poly(vinyl alcohol)nanocomposite membranes(AgNPs-PVA)are produced for the sake of improving its potentials for pervaporation of ethanol–water mixture so that the usual opposite trend between membrane selectivity and permeation can be reduced.The nanocomposite membranes are fabricated from an aqueous solution of poly(vinyl alcohol)with silver nanoparticles via the in-situ generation technique in the absence of any reducing agent.Successful generation of the nano size silver is measured by the UV–vis spectrum showing a single peak at 419 nm due to the plasmonic effect of silver nanoparticles.Our nanocomposite AgNPs-PVA membranes are characterized using scanning electron microscope(SEM),Fourier-transform infrared(FT-IR)spectroscopy,X-ray diffraction and thermogravimetric analysis(TGA).The pervaporation tests of our new AgNPs-PVA membranes show good results since at a higher temperature and higher ethanol concentration in the feed,the prepared membranes are highly permeable for the water having stable selectivity values and therefore our membranes show better performance compared to that of the other PVA-based nanocomposite membranes. | Asmaa Selim Andras Jozsef Toth Daniel Fozer Eniko Haaz Nóra Valentínyi Tibor Nagy Orsolya Keri Lászlo Péter Bakos Imre Miklós Szilágyi Peter Mizsey | 2019 | Chinese Journal of Chemical Engineering2019，27，7： | 0 |
| 20 | HIV among people who inject drugs in Hungary显示文摘Background:Before 2014(the year of closure of the two largest needle exchange programs in Hungary,which halved the number of available syringes in the country despite increased injecting risk practices)no HIV was reportedly acquired in Hungary among people who inject drugs(PWIDs)who were not also men who had sex with other men(MSM).In 2014,one and in 2015 two non-MSM PWIDs were newly diagnosed with HIV who supposedly became infected in Hungary,and both incident HIV cases in 2015 were diagnosed in the AIDS stage.In addition,two new(albeit supposedly imported)non-MSM PWID cases were also registered in the first three quarters of 2016,one of which subsequently was diagnosed with and then died of AIDS.At the same time,the prevalence of HCV doubled among PWIDs(from 24%to 49%in Hungary and from 34%to 61%in Budapest).Case presentation:The case that we discuss in this paper is a male PWID,who was diagnosed with HIV and AIDS in May of 2015 and then died of AIDS the next month.His HIV infection status was detected with delay,and then appeared in the official statistics as an incident PWID HIV case and an incident PWID AIDS case,but not as an incident PWID AIDS death.No contact tracing followed,even though it would have been relatively easy considering the circumstances.To our knowledge,no HIV post-exposure protocol exists in hospitals,in case of HIV exposure due to an eventual needle-stick injury.Conclusions:Our paper draws attention to recently published HIV and AIDS surveillance data,and shows the failure of the system.While sounding the alarm based on three newly detected PWID HIV cases in the past 2 years may be premature,there are definitely serious problems in the HIV detection and tracing system among PWIDs in Hungary. | Andras Ortutay VAnna Gyarmathy Zsuzsa Marjanek Karoly Nagy Jozsef Racz Istvan Barcs | 2017 | Infectious Diseases of Poverty2017，6，1： | 0 |
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