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| 1 | Relative peripheral refraction across 4 meridians after orthokeratology and LASIK surgery显示文摘Background:To characterize the axial and off-axis refraction across four meridians of the retina in myopic eyes before and after Orthokeratology(OK)and LASIK surgery.Methods:Sixty right eyes with a spherical equivalent(M)between−0.75 to−5.25 D(cylinder<−1.00 D)underwent LASIK(n=26)or OK(n=34)to treat myopia.Axial and off-axis refraction were measured with an open-field autorefractometer before and after stabilized treatments.Off-axis measurements were obtained for the horizontal(35°nasal and temporal retina)and vertical(15°superior and inferior retina)meridians,and for two oblique directions(45–225°and 135–315°)up to 20°of eccentricity.The refractive profile was addressed as relative peripheral refractive error(RPRE).Results:OK and LASIK post-treatment results showed an increase of myopic relative refraction at several eccentric locations.At the four meridians evaluated,the M component of the pre-treatment RPRE values was not statistically different(p>0.05)from the post-treatment RPRE within 30°and 20°of the central visual field after LASIK and OK,respectively.These results demonstrated that the treatment zone warrants an optimal central field of vision.Conclusions:The present study gives an overview of RPRE after refractive corneal reshaping treatments(OK and LASIK)across vertical,horizontal and two oblique meridians together.This allows a 3D representation of RPRE at the retina and shows that the myopic shift induced by both treatments is more relevant in horizontal directions. | António Queirós Ana Amorim-de-Sousa Daniela Lopes-Ferreira César Villa-Collar Ángel Ramón Gutiérrez JoséManuel González-Méijome | 2018 | Eye and Vision2018，5，1： | 8 |
| 2 | Focal liver lesions:Practical magnetic resonance imaging approach显示文摘With the widespread of cross-sectional imaging, a growth of incidentally detected focal liver lesions(FLL) has been observed. A reliable detection and characterization of FLL is critical for optimal patient management. Maximizing accuracy of imaging in the context of FLL is paramount in avoiding unnecessary biopsies, which may result in post-procedural complications. A tremendous development of new imaging techniques has taken place during these last years. Nowadays, Magnetic resonance imaging(MRI) plays a key role in management of liver lesions, using a radiation-free technique and a safe contrast agent profile. MRI plays a key role in the non-invasive correct characterization of FLL. MRI is capable of providing comprehensive and highly accurate diagnostic information, with the additional advantage of lack of harmful ionizing radiation. These properties make MRI the mainstay for the noninvasive evaluation of focal liver lesions. In this paper we review the state-of-the-art MRI liver protocol, briefly discussing different sequence types, the unique characteristics of imaging non-cooperative patients and discuss the role of hepatocyte-specific contrast agents. A review of the imaging features of the most common benign and malignant FLL is presented, supplemented by a schematic representation of a simplistic practical approach on MRI. | António P Matos Fernanda Velloni Miguel Ramalho Mamdoh AlObaidy Aruna Rajapaksha Richard C Semelka | 2015 | World Journal of Hepatology2015，7，16： | 6 |
| 3 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 4 | 金龟子绿僵菌分生孢子暴露在B段紫外光下毒力的降低显示文摘The UV-A and UV-B wavelengths of solar radiation may seriously reduce viability of Metarhizium anisopliae conidia,a fungus used extensively in Brazil for insect pest control.The conidial tolerances to UV-A and UV-B radiation were studied for one isolate(IBCB 425) commercially available product produced on rice grains.Aqueous or oil emulsion conidial suspensions were irradiated for 0(control),2,or 3 h using the solar simulator filtered with diacetate filter to remove UV-C radiation which afforded 652 mW·m-2 in the spectral range of 280~370 nm.The UV tolerance was based on conidial germination(viability) and virulence to Diatraea saccharalis larvae.Conidia formulated with oil emulsion had higher survival after 3 h of UV exposure,but the virulence of the conidia previously exposed to 2 h of UV radiation were similar when oil formulated or not.The mortality of D.saccharalis caterpillars exposed to non-UV-irradiated conidia was greater than that of larvae exposed to irradiated conidia,and the LT50 values were lower for the non-irradiated suspensions than for those irradiated.This apparent reduction in virulence was directly related reduction in viability or delay of germination of UV-irradiated conidia. | Edimara A Francisco Drauzio E N Rangel Newton La Scala Jr José C Barbosa Antnia do C B Correia | 2008 | 安徽农业大学学报2008，35，2： | 2 |
| 5 | Propranolol for severe hemangiomas of infancy显示文摘 | Léanté-Larèze C Dumas de la Roque E Huhiche T | | 0，，24： | 1 |
| 6 | Internal fixation of the lumbar spine with pedicle screw plating显示文摘 | Roy-Camile R Sail ant G Mazel C | | 0，，： | 1 |
| 7 | Buckling strength of multi-story sway, non-sway and partially-sway frames with semi-rigid connections 显示文摘 | MAGEIROU G E ( -ANTES C J | 2006 | Journal of Constructional Steel Research2006，62，9： | 1 |
| 8 | Serum immunoglobulin G antibody to Porphyromonas gingivalis in rapidly progressive periodontitis:titer,avidity,and subclass distribution显示文摘 | Whitney C Ant J Monela B | 1992 | Infect Immun1992，60，6： | 1 |
| 9 | NOD2/CARD15 and TNFA, but not IL1B and IL1RN, are associated with Crohn’s disease显示文摘 | António CarlosFerreira SusanaAlmeida MartaTavares PauloCanedo FábioPereira Gon?aloRegalo CéuFigueiredo EuniceTrindade RaquelSeruca FátimaCarneiro JorgeAmil José CarlosMachado FernandoTavarela‐Veloso | 2006 | Inflamm Bowel Dis2006，，4： | 1 |
| 10 | 显示文摘 | Reynolds D C Leies G Antes L T | 1954 | PhysRev1954，96，： | 1 |
| 11 | A TALEN-based strategy for efficient bi-allelic miRNA ablation in human cells 显示文摘 | Uhde-Stone C Sarkar N Antes T | 2014 | RNA2014，20，6： | 1 |
| 12 | Comprehensive concretefracture tests: size effects of types 1 & 2, crack lengtheffect and post peak 显示文摘 | HOOVER C G BA譕ANT Z P | 2013 | Engineering FractureMechanics2013，110，2： | 1 |
| 13 | Modeling the effects of initial spacing on stand basal area development of loblolly pine显示文摘 | ANTN-FERNNDEZ C BURKHART H E AMATEIS R L | 2012 | Forest Science2012，58，2： | 1 |
| 14 | A new intravenous fat emul sion containing soybean oil, medium-chain triglycerides, olive oil,and fish oil: a single-center, double-blind randomized study on ef- ficacy and safety in pediatric patients receiving home parenteral nutrition显示文摘 | Goulet O Ant~bi H Wolf C | 2010 | J Parenter Enteral Nutr2010，34，5： | 1 |
| 15 | Diagnosis and follow-up of infections in intensive care patients: value of C-reactive protein compared with other clinical and biological variables显示文摘 | Reny JL Vuagnat A R ant C | 2002 | Crit Care Med2002，30，： | 1 |
| 16 | Sodium Isopropyl Xanthate Degradation by Advanced Oxidation Processes显示文摘 | Gerardo Cifuentes Molina Cármen Herrera Cayo Marco Ant?nio Siqueira Rodrigues Andréa Moura Bernardes | 2012 | Minerals Engineering2012，，： | 1 |
| 17 | Physical exercise prevents and mitigates non-alcoholic steatohepatitis-induced liver mitochondrial structural and bioenergetics impairments显示文摘 | Inês O. Gon?alves Emanuel Passos Silvia Rocha-Rodrigues Cátia V. Diogo Joan R. Torrella David Rizo Ginés Viscor Estela Santos-Alves Inês Marques-Aleixo Paulo J. Oliveira António Ascens?o José Magalh?es | 2014 | Mitochondrion2014，，： | 1 |
| 18 | IRECS:a new algorithm for the selection of most probable ensembles of side-chain conformations in protein models显示文摘 | Hartmann C Antes I Lengauer T | 2007 | Protein Sci2007，16，7： | 1 |
| 19 | Comparative genomies of MAP kinase and calcium calcineurin signaling components in plant and human pathogenic fungi 显示文摘 | Rispail N Soanes D M Ant C et cd | 2009 | Fung Genet Biol2009，46，2： | 1 |
| 20 | The Tat pathway of plant pathogen Dickeya dadantii 3937contributes to virulence and fitness显示文摘 | Rodríguez-Sanz M Antúnez-Lamas M Rojas C | 2010 | Fems Microbiology Letters2010，302，2： | 1 |
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