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| 1 | Efficacy and safety of tenofovir disoproxil fumarate in pregnancy for the prevention of vertical transmission of HBV infection显示文摘AIM:To evaluate the effects of tenofovir disoproxil fumarate(TDF)use during late pregnancy to reduce hepatitis B virus(HBV)transmission in highly viremic mothers.METHODS:This retrospective study included 45 pregnant patients with hepatitis B e antigen(+)chronic hepatitis B and HBV DNA levels>107copies/mL who received TDF 300 mg/d from week 18 to 27 of gestation(n=21).Untreated pregnant patients served as controls(n =24).All infants received 200 IU of hepatitis B immune globulin(HBIG)within 24 h postpartum and 20μg of recombinant HBV vaccine at 4,8,and 24 wk.Perinatal transmission rate was determined by hepatitis B surface antigen and HBV DNA results in infants at week 28.RESULTS:At week 28,none of the infants of TDFtreated mothers had immunoprophylaxis failure,whereas2(8.3%)of the infants of control mothers had immunoprophylaxis failure(P=0.022).There were no differences between the groups in terms of adverse events in mothers or congenital deformities,gestational age,height,or weight in infants.At postpartum week 28,significantly more TDF-treated mothers had levels of HBV DNA<250 copies/mL and normalized alanine aminotransferase compared with controls(62%vs none,P<0.001;82%vs 61%,P=0.012,respectively).CONCLUSION:TDF therapy during the second or third trimester reduced perinatal transmission rates of HBV and no adverse events were observed in mothers or infants. | Mustafa Kemal Celen Duygu Mert Müzeyyen Ay Tuba Dal Safak Kaya Necmettin Yildirim Serda Gulsun Tunga Barcin Sevgi Kalkanli Mehmet Sinan Dal Celal Ayaz | 2013 | World Journal of Gastroenterology2013，19，48： | 26 |
| 2 | 肺动脉高压患者的负荷适应性显示文摘已知右心室对压力超负荷的适应是肺动脉高压(pulmonary arterial hypertension,PAH)患者预后的主要影响因素。为了评估右心室适应和负荷之间的关系,然后比较PAH中不同负荷适应性指数的预后价值,Amsallem及其同事纳入推导队列(n=85)和验证队列(n=200),使用3种方法评估负荷适应性:①脑室动脉耦合的替代物(例如右心室面积变化/收缩末期面积); | 刘莉 叶鹏 Amsallem M Boulate D Aymami M Guihaire J Selej M Huo J Denault AY McConnell MV Schnittger I Fadel E Mercier O Zamanian RT Haddad F | 2017 | 中华高血压杂志2017，25，8： | 2 |
| 3 | 强化与标准降压治疗对脑卒中亚型的影响显示文摘在收缩压干预试验(systolic blood pressure intervention trial, SPRINT)中,各治疗组的脑卒中发生比例差异无统计学意义,但脑卒中亚型的病因不同,可能对强化降压治疗的反应不同。SPRINT纳入患者(n=9 361)随机分为目标收缩压<120 mm Hg(1 mm Hg=0.133 kPa)的强化治疗与目标收缩压<140 mm Hg的标准治疗组。 | Wright CB Auchus AP Lerner A Ambrosius WT Ay H Bates JT Chen J Meschia JF Pancholi S Papademetriou V Rastogi A Sweeney M Willard JJ Yee J Oparil S 赵狄(摘译) 郑武洪(审校) | 2021 | 中华高血压杂志2021，29，3： | 2 |
| 4 | 高度近视伴色觉缺失的家系分析(英文)显示文摘目的:评估高度近视伴色觉缺失患者的遗传学特征和临床表现方法:就同一家族4代42个成员中有8位患者给予了详细的眼科检查,Ishihara盘和FM100H试验检测患者有无红绿色觉缺失,全视野视网膜电图评价其视网膜功能。结果:患者8位均因高度近视视力下降,其中6例有红绿色觉缺失,眼底检查显示以弥漫性视网膜脉络膜萎缩为特征的近视改变。2例患者ERG检查出现视杆细胞的暗适应异常和视锥细胞的反应消失,根据家系,红绿色觉缺失属X连锁的隐性遗传。结论:在这个家族成员中,同时发生的高度近视和色觉缺失可能有共同的遗传学基础。 | Nimet nay Gündogan Ay■e Gül Koak Altinta■ Nezih Durmazlar Koray Gümüs Zerrin Yilmaz Kemal Ksemehmetoglu | 2007 | 国际眼科杂志2007，7，3： | 2 |
| 5 | Inflammation, residualkidney function, and cardiac hypertrophy are interrelated and combine adversely to enhance mortality and ardiovasculardeath risk of peritoneal dialysis patients 显示文摘 | Wang AY Wang M Woo J | 2004 | J Am Soc Nephrol2004，15，： | 1 |
| 6 | cPLA2 is phosphorylated and activated by MAP kinase显示文摘 | Lin LL Wartmann M Lin AY | 1993 | Cell1993，72，2： | 1 |
| 7 | Correlation between NT proBNP andleft ventricular ejection fraction in elderly patients presenting to e- mergency department with dyspnoea显示文摘 | Belagavi AC Rao M Pillai AY | 2012 | Indian Heart J2012，64，： | 1 |
| 8 | New inorganic sorbent for Ion-selective purification of liquid radioactive wastes显示文摘 | Sharygin M Muromskii AY | 2000 | Atomic Energy2000，2，： | 1 |
| 9 | Mechanism and function of deu- biquitinating enzymes 显示文摘 | Amerik AY Hochstrasser M 2004 | 2004 | Biochimica et Biophysica Acta Bioen- ergetics2004，1695，13： | 1 |
| 10 | Green energy strategies for sustainable development显示文摘 | Midilli A Dincer I Ay M | 2006 | Energy Policy2006，34，18： | 1 |
| 11 | Role of hypoxia-inducible factor-l in hypoxia-induced ischemic tolerance in neonatal rat brain显示文摘 | Bergeron M Gidday JM Yu AY | 2000 | Ann Neu- rol2000，48，3： | 1 |
| 12 | Role of hypoxia- inducible factor-1 in hypoxia-induced ischemic tolerance in neonatal rat brain显示文摘 | Bergeron M Gidday JM Yu AY | 2000 | Ann Neurol2000，48，3： | 1 |
| 13 | Clinical- and imaging-based prediction of stroke risk after transient ischemic attack: theCIP model显示文摘 | Ay H Arsava E M Johnston S C | 2009 | Stroke2009，40，： | 1 |
| 14 | Heart failure in long - term peritoneal dialysis patients: a 4-year prospective analysis 显示文摘 | Wang AY Wang M Lam CW | 2011 | Clin J Am Socof Nephrol2011，6，4： | 1 |
| 15 | FOXP3 and NFAT: partners in tolerance 显示文摘 | Rudensky AY Gavin M Zheng Y | 2006 | Cell2006，126，2： | 1 |
| 16 | Role of hypoxia-induciblefactor-1 in hypoxia-induced ischemic tolerance in neonatal rat brain显示文摘 | Bergeron M Gidday JM Yu AY | | 0，，： | 1 |
| 17 | Milrinone enhances systolic,but not diastolic function during coronary artery bypass grafting surgery显示文摘 | Couture P Denault AY Pellerin M | | 0，，07： | 1 |
| 18 | Glucocorticoid corticosteroids for Duchenne muscular dystrophy 显示文摘 | Manzur AY Kuntzer T Pike M | 2008 | Cochrane Database Syst Rev2008，，13： | 1 |
| 19 | The non-structural polyprotein 3ABC of foot-and-mouth disease virus as a diagnostic antigen in ELISA to differentiate infected from vaccinated cattle显示文摘 | DE DIEGO M BROCCHI E MACK AY D | 1997 | Arch Virol1997，142，10： | 1 |
| 20 | Effect of peri-opera-tive red blood cell transfusion on 30-day and 1-year mortalityfollowing coronary artery bypass surgery显示文摘 | Kuduvalli M Oo AY Newall N | 2005 | Eur J CardiothoracSurg2005，27，4： | 1 |
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