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| 1 | Model for end-stage liver disease score versus Child score in predicting the outcome of surgical procedures in patients with cirrhosis显示文摘AIM:To determine factors affecting the outcome of patients with cirrhosis undergoing surgery and to compare the capacities of the Child-Turcotte-Pugh(CTP) and model for end-stage liver disease(MELD)score to predict that outcome. METHODS:We reviewed the charts of 195 patients with cirrhosis who underwent surgery at two teaching hospitals over a five-year period.The combined endpoint of death or hepatic decompensation was considered to be the primary endpoint. RESULTS:Patients who reached the endpoint had a higher MELD score,a higher CTP score and were more likely to have undergone an urgent procedure.Among patients undergoing elective surgical procedures,no statistically significant difference was noted in the mean MELD(12.8±3.9 vs 12.6±4.7,P=0.9)or in the mean CTP(7.6±1.2 vs 7.7±1.7,P=0.8)between patients who reached the endpoint and those who did not.Both mean scores were higher in the patients reaching the endpoint in the case of urgent procedures(MELD:22.4± 8.7 vs 15.2±6.4,P=0.0007;CTP:9.9±1.8 vs 8.5±1.8, P=0.008).The performances of the MELD and CTP scores in predicting the outcome of urgent surgery were only fair,without a significant difference between them (AUC=0.755±0.066 for MELD vs AUC=0.696±0.070 for CTP,P=0.3). CONCLUSION:The CTP and MELD scores performedequally,but only fairly in predicting the outcome of urgent surgical procedures.Larger studies are needed to better define the factors capable of predicting the outcome of elective surgical procedures in patients with cirrhosis. | Maarouf A Hoteit Amaar H Ghazale Andrew J Bain Eli S Rosenberg Kirk A Easley Frank A Anania Robin E Rutherford | 2008 | World Journal of Gastroenterology2008，14，11： | 16 |
| 2 | 抗炎介质表达缺陷参与中性粒细胞型支气管哮喘发病机制:半乳糖凝集素-3和白细胞介素-1RA/白细胞介素-1beta比例显著下降显示文摘支气管哮喘(哮喘)是具有异质性的气道炎症性疾病,其主要特点表现为气道高反应和可变的气流受限。在哮喘的发病机制中,过敏原诱导的TH2淋巴细胞激活以及IL-5介导的嗜酸粒细胞渗出起到重要的作用。近年来发现超过50%的哮喘患者气道的嗜酸粒细胞水平并不增高,并将这种亚型定义为非嗜酸粒细胞型哮喘。其中部分患者表现为气道中性粒细胞明显增高,称为中性粒细胞型哮喘。 | 高鹏 Peter G Gibson Katherine J Baines Ian A Yang John W Upham Paul N Reynolds Sandra Hodge Alan L James Christine Jenkins Matthew J Peters 张捷 Jodie L Simpson | 2016 | 中华结核和呼吸杂志2016，39，11： | 5 |
| 3 | High level expression of hepatitis B viral antigens in fibrosing cholestatic hepatitis 显示文摘 | Lau J Y N Davis GL Bain V G | 1992 | Gastroenterology1992，102，： | 1 |
| 4 | Human host defence peptide LL -37 prevents bacterial biofilm formation 显示文摘 | OVERHAGE J CAMPISANO A BAINS M | 2008 | hd''eet Immun2008，76，9： | 1 |
| 5 | Giant benign esophageal schwannoma requiring esophagectomy显示文摘 | Park B J Carrasquillo J Bains M S | 2006 | Ann Thorac Surg2006，82，1： | 1 |
| 6 | Construction of a whole-cell gene reporter for the fluorescent bioassay of nitrate 显示文摘 | Taylor C J Bain L A Richardson D J | 2004 | Anal Biochem2004，328，1： | 1 |
| 7 | Proteins of the outer layer of the vitelline membrane of hen's eggs显示文摘 | BACK J BAIN J VADEHRA D | 1982 | Biochem Biophys Acta1982，70，5： | 1 |
| 8 | The natural flow regime--A paradigm for river conservation and restoration 显示文摘 | Poff N L Allan J D Bain M B | 1997 | Bioscience1997，47，： | 1 |
| 9 | Construction of a whole-cell gene reporter for the fluorescent bioassay of nitrate显示文摘 | Taylor C J Bain L A Richardson DJ | 2004 | Anal Biochem2004，328，1： | 1 |
| 10 | Energy-storage technologies and electricity generation显示文摘 | HALL P J BAIN E J | 2008 | Energy Policy2008，36，12： | 1 |
| 11 | Decreased thin filament density and length in human atrophic soleus muscle fibers after spaceflight显示文摘 | Riley D A Bain J L Thompson J L | 2000 | J Appl Physiol2000，88，2： | 1 |
| 12 | Establishment of primary and continuous cultures of epithelial cells from larval lepidopteran midguts显示文摘 | Baines D Brownwright A Schwartz J L | 1994 | Insect Phyiol1994，40，4： | 1 |
| 13 | Probability of correct selection of Weibull versus gamma based on likelihood ratio 显示文摘 | Bain L J Engelhardt M | 1980 | Commun Stat Theory Method1980，9，： | 1 |
| 14 | The natural flow regime: A paradigm for river conservation and restoration 显示文摘 | Poff N L Allan J D Bain M B | 1997 | Bioscience1997，47，11： | 1 |
| 15 | The reaction of β-pinene with formaldehyde显示文摘 | BAIN J P NOPOL I | 1946 | J Am Chem Soc1946，，68： | 1 |
| 16 | Spectrin and ankyrin-based path- ways: metazoan inventions for integrating cells into tissues 显示文摘 | BENNETT V BAINES A J | 2001 | Physiological Reviews2001，81，3： | 1 |
| 17 | The selectivity of protein kinase inhibitors : a further update 显示文摘 | Bain J Plater L Elliott M | 2007 | Biochem J2007，408，： | 1 |
| 18 | Use of the ASA physical status system in pediatric practice 显示文摘 | Aplin S Baines D l)e Lima J | 2007 | Paediatr Anaesth2007，17，3： | 1 |
| 19 | The role of biomar- kers in the management of airways disease显示文摘 | Baines K J Pavord ID2 Gibson PG | 2014 | Int J Tuberc Lung Dis2014，18，11： | 1 |
| 20 | The natural flow regime--a paradigm for river conservation and restoration 显示文摘 | Poff N L Allan J D Bain M B | 1997 | Bioscience1997，47，： | 1 |
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