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| 1 | Effect of B vitamin supplementation on plasma homocysteine levels in celiac disease显示文摘AIM: To investigate the effect of vitamin supplements on homocysteine levels in patients with celiac disease. METHODS: Vitamin B6, folate, vitamin B12, and fasting plasma homocysteine levels were measured in 51 consecutive adults with celiac disease [median (range) age 56 (18-63) years; 40% men, 26 (51%) had villous atrophy, and 25 (49%) used B-vitamin supplements] and 50 healthy control individuals matched for age and sex. Finally, the C677T polymorphism of 5,10-methylene tetrahydrofolate reductase (MTHFR) was evaluated in 46 patients with celiac disease and all control individuals. RESULTS: Patients with celiac disease and using vitamin supplements had higher serum vitamin B6 (P = 0.003),folate (P < 0.001), and vitamin B12 (P = 0.012) levels than patients who did not or healthy controls (P = 0.035, P < 0.001, P = 0.007, for vitamin B6, folate, and vitamin B12, respectively). Lower plasma homocysteine levels were found in patients using vitamin supplements than in patients who did not (P = 0.001) or healthy controls (P = 0.003). However, vitamin B6 and folate, not vitamin B12, were significantly and independently associated with homocysteine levels. Twenty-four (48%) of 50 controls and 23 (50%) of 46 patients with celiac disease carried the MTHFR thermolabile variant T-allele (P = 0.89). CONCLUSION: Homocysteine levels are dependent on Marsh classification and the regular use of B-vitamin supplements is effective in reduction of homocysteine levels in patients with celiac disease and should be considered in disease management. | Muhammed Hadithi Chris JJ Mulder Frank Stam Joshan Azizi J Bart A Crusius Amado Salvador Pea Coen DA Stehouwer Yvo M Smulders | 2009 | World Journal of Gastroenterology2009，15，8： | 3 |
| 2 | Regulatory role of SGTI in early R Gene-Mediated plant defenses显示文摘 | Mark J Paul M Katherine K Bart J Jonathan D G Jane E | 2002 | Science2002，295，15： | 1 |
| 3 | Recent advances and application in the field of short-term traffic forecasting显示文摘 | van Arem Bart Kirby Howard R Van Der Vlist Martie J M | 1997 | International Journal of Forecasting1997，13，： | 1 |
| 4 | Modeling of induced anisotropic damage in granites显示文摘 | SHAO J F HOXHA D BART M | 1999 | International Journal of Rock Mechanics and Mining Sciences1999，36，8： | 1 |
| 5 | Design and Energetic Characterization of a Liquid Propellant Powered Actuator for Self--powered Robots显示文摘 | Goldfarb M Bart E J Gogola M A | 2003 | IEEE/ASME Transactions on Mechanics2003，8，2： | 1 |
| 6 | Echocardiographic quantification of myocardial function using tissue deformation imaging,a guide to image acquisition and analysis using tissue Doppler and speckle tracking显示文摘 | ARCO J T BART W L D B PAUL G M | 2007 | Cardiovasc Ultrasound2007，5，3： | 1 |
| 7 | Concomitant activation of jasmonate and thylene response pathways is required for induction of a plant defensin gene in Arabidopsis显示文摘 | Thomma Bart P J Buchala A | 1998 | The Plant Cell1998，10，： | 1 |
| 8 | Transoral Incisionless Fundoplication: 2-year Results from the Prospective Multicenter U.S. Study显示文摘 | Bell Reginald C W Barnes William E Carter Bart J Sewell Robert W Mavrelis Peter G Ihde Glenn M Hoddinott Kevin M Fox Mark A Freeman Katherine D Gunsberger Tanja Hausmann Mark G Dargis David Gill Brian DaCosta Wilson Erik Trad Karim S | 2014 | The American Surgeon2014，，11： | 1 |
| 9 | An HIV-1 clade C DNA prime,NYVAC boost vaccine regimen induces reliable,polyfunctional,and long-lasting T cell responses显示文摘 | Harari A Bart PA St(o)hr W Tapia G Garcia M Medjitna-Rais E Burnet S Cellerai C Erlwein O Barber T Moog C Liljestrom P Wagner R Wolf H Kraehenbuhl JP Esteban M Heeney J Frachette MJ Tartaglia J McCormack S Babiker A Weber J Pantaleo G | 2008 | J Exp Med2008，205，1： | 1 |
| 10 | Biomarkers in upper Holocene Eastern North Sea and Wadden Sea sediments显示文摘 | BART E VD W IC R CATHARINA J M P | 2000 | Organic Geochemistry2000，31，： | 1 |
| 11 | Molecular cloning and nucleotide sequence of hog cholera envelope glycoprotein EI 显示文摘 | Moonmann R J M Warmendarm P A M Bart V M | 1990 | Virology1990，177，： | 1 |
| 12 | CNS origins of sympathetic nervous system outflow to brown adipose tissue显示文摘 | BAMSHAD M SONG C K BARTNESS T J | 1999 | Am J Physiol1999，276，62： | 1 |
| 13 | Community based innovation: How to integrate members of virtual communities into new product development 显示文摘 | FULLER J BART L M ERNST H | 2006 | Electronic Commerce Research2006，6，1： | 1 |
| 14 | An alternation fluorescence ehancement solution for use in lanthanide based time-resolved fluoroimmunoassay显示文摘 | KEELAN J A FRANCE J T BARTING P M | 1978 | Clin Chem1978，33，： | 1 |
| 15 | Development of a service-simulating, accelerated aging testmethod for exterior tire rubber compounds 显示文摘 | DENG H’BART J LACOUNTJOSE M CASTRO | 2001 | PolymerDegradationand Stability2001，74，2： | 1 |
| 16 | An alternation fluorescence ehancement solution for use in lanthanide based time-fluoroimmunoassay显示文摘 | KEELAN J A FRANCE J T BARTING P M | 1978 | Clin Chem1978，33，： | 1 |
| 17 | The dialysis diet and fluid non-adherence questionnaire:validity testing of a self-report instrument for clinical practice显示文摘 | Bart M An J | 2001 | Journal of Clinical Nursing2001，10，： | 1 |
| 18 | Corticotropin-releasing factor testing reveals a dose-dependent difference in methadone maintained vs control subjects显示文摘 | Schluger J H Bart G Green M | 2003 | Neuropsychopharmacology2003，28，5： | 1 |
| 19 | New resolving bases for ibuprofen and mandelic acid : qualification by binary phase diagrams 显示文摘 | EELCO J E BART J M P GERRY J A A | 1997 | Tetrahedron : Asymmetry1997，8，24： | 1 |
| 20 | Overexpression of the endoplasmic reticulum chaperone BiP3 regulates XA21-mediated innate immunity in rice显示文摘 | Park C J Bart R Chem M | 2002 | Science2002，28，7： | 1 |
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