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54篇 您的检索式：作者名="BONAFE L"

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	题名	作者	年代	出处	被引量
1	Circulating leptin and its muscle gene expression in Nellore cattle with divergent feed efficiency显示文摘Background: Leptin has a strong relation to important traits in animal production, such as carcass composition,feed intake, and reproduction. It is mainly produced by adipose cells and acts predominantly in the hypothalamus.In this study, circulating leptin and its gene expression in muscle were evaluated in two groups of young Nellore bulls with divergent feed efficiency. Individual dry matter intake(DMI) and average daily gain(ADG) of 98 Nellore bulls were evaluated in feedlot for 70 d to determinate the residual feed intake(RFI) and select 20 animals for the high feed efficient(LRFI) and 20 for the low feed efficient(HRFI) groups. Blood samples were collected on d 56 and at slaughter(80 d) to determine circulating plasma leptin. Samples of Longissimus dorsi were taken at slaughter for leptin gene expression levels.Results: DMI and RFI were different between groups and LRFI animals showed less back fat and rump fat thickness,as well as less pelvic and kidney fat weight. Circulating leptin increased over time in all animals. Plasma leptin was greater in LRFI on 56 d and at slaughter(P = 0.0049). Gene expression of leptin were greater in LRFI animals(P = 0.0022) in accordance with the plasma levels. The animals of the LRFI group were leaner, ate less, and had more circulating leptin and its gene expression.Conclusion: These findings demonstrated that leptin plays its physiological role in young Nellore bulls, probably controlling food intake because feed efficient animals have more leptin and lower residual feed intake.	Lúcio Flávio Macedo Mota Cristina Moreira Bonafé Pamela Almeida Alexandre Miguel Henrique Santana Francisco JoséNovais Erika Toriyama Aldrin Vieira Pires Saulo da Luz Silva Paulo Roberto Leme JoséBento Sterman Ferraz Heidge Fukumasu	2018	Journal of Animal Science and Biotechnology2018，9，1：	3
2	TLR9-targeted biodegradable nanoparticles as immunization vectors protect a?gainst West Nile encephalitis显示文摘	DEMENTO S L BONAFE N CUI W G	2010	J Immunol2010，185，5：	1
3	Ultrastructural and histochemical examination of alveolar bone at the pressure areas of rat molars submitted to continuousorthodontic force显示文摘	Bonafe Oliveira L Faltin RM Arana Chavez VE	2003	Eur J Oral Sci2003，111，：	1
4	DNA polymorphisms of the KiSS1 3'Untranslated region interfere with the folding of a G-rich sequence into G-quadruplex显示文摘	Huijbregts L Roze C Bonafe G		0，，02：	1
5	Mutations in the sepiapterin reductase gene cause a novel tetrahydrobiopterin-dependent monoamine-neurotransmitter deficiency without hyperphenylalaninemia显示文摘	BONAFE L THONY B PENZIEN J M	2001	Am J Med Genet2001，69，2：	1
6	Extended tetrahydrobiopterin loading test in the diagnosis of cofactorresponsive phenylketonuria显示文摘	FIEGE B BONAFE L BALLHAUSEN D	2005	A Pilot Study2005，86，：	1
7	Endovascular treatment of intracrani-al aneurysms using Matrix coils:short-and mid-term results in ruptured and unruptured aneurysms显示文摘	Pierot L Leclrc X Bonafe A	2008	Neurosurgery2008，63，1：	1
8	Metabolic gene polymorphisms and p53 mutations in healthy centenarians and younger controls 显示文摘	Gaspari L Pedotti P Bonafe M	2003	Biomarkers2003，8，6：	1
9	Endovascular treatment of intracranial aneurysms with matrix detachable coils: midterm anatomic follow-up from a prospective multicenter registry 显示文摘	Pierot L Leclerc X Bonafe A	2008	AJNR2008，29，：	1
10	Evaluation of urinary acylglycines by electrospray tandem mass spectrometry in mitochondrial energy metabolism defects and organic acidurias显示文摘	Bonafe L Troxler H Kuster T	2000	Mol Genet Metab2000，69，4：	1
11	p66 (shc) is highly expressed in fibroblasts from centenarians显示文摘	Pandolfi S Bonafe M Di Tella L	2005	Mech Ageing Dev2005，126，8：	1
12	Endovascular treatment of intracranial aneurysms with Matrix detachable coils: midterm anatomic follow-up from a prospective multicenter registry 显示文摘	Pierot L Leclerc X Bonafe A	2008	AJNR2008，29，：	1
13	Mutations in the sepiapterin reductase gene cause a novel tetra hydrobiopterin dependent monoamine neurotransmitter deficiency without hyperphenylalaninemia 显示文摘	Bonafe L Thony B Penzien J M	2001	The American Journal of Human Genetics2001，69，2：	1
14	Metabolic gene polymor- phisms and p53 muta tions in healthy centenarians and younger controlsp显示文摘	Gaspari L Pedotti P Bonafe M	2003	Biomarkers2003，8，6：	1
15	Mutations in the sepiapterin reductase gene cause a novel tetrahydrobiopterin-dependent monoamine-neurotransmitter deficiency without hyperphenylalaninemia显示文摘	Bonafé L Th6ny B Penzien JM	2001	Am J Hum Genet2001，69，2：	1
16	Diagnosis of dopa-responsive dystonia and other tetrahydrobiopterin disorders by the study of biopterin metabolism in fibroblasts显示文摘	Bonafe L Thony B Leimbacher W	2001	Clin Chem2001，47，3：	1
17	Tetrahydrobiopterin deficiencies without hyperphenylalaninemia:diagnosis and genetics of dopa-responsive dystonia and sepiapterin reductase deficiency显示文摘	Blau N Bonafé L Th(o)ny B	2001	Mol Genet Metab2001，74，12：	1
18	The unsolved puzzle of neuropathogenesis in glutaric aciduria type Ⅰ显示文摘	Jafari P Braissant O Bonafe L		Molecular Genetics and Metabolism0，，：	1
19	Tetrahydrobiopterin deficiencies without hyperphenylalaninemia: diagnosis and genetics of dopa-responsive dystonia and sepiapterin reductase deficiency显示文摘	Blau N Bonafe L Thony B	2001	Molecular genetics and metabolism2001，74，1：	1
20	DTDST mutations are not a frequent cause of idiopathictalipes equinovarus (club foot)显示文摘	L Bonaf é S H Blanton A Scott S Broussard C A Wise A Superti-Furga J T Hecht	2002	J Med Genet2002，39，：	1

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