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| 1 | Nodoventricular accessory pathways in PRKAG2-dependent familial preexcitation syndrome reveal a disorder incardiac development显示文摘 | Tan H L van der Wal A C Campian M E Kruyswijk H H Bram T H J van Doorn D J | 2008 | Circ Arrhythm Electrophysiol2008，1，： | 1 |
| 2 | Thyroid function during pregnancy with special reference to hydatidi-form mole and hyperemesis 显示文摘 | BRAM T KRISTOFFERSEN K | 1978 | Acta Endocrinol1978，88，： | 1 |
| 3 | Renal Ca2+ wasting,hyperabsorption,and reduced bone thickness in micelacking TRPV 5 显示文摘 | Hoenderop Joost G J van Leeuwen Johannes P T M van der Eerden Bram C J | 2003 | J Clin Invest2003，112，： | 1 |
| 4 | Going green to be seen: status, reputation, and conspicuous conservation 显示文摘 | Vladas Griskevicius Bram Van den Bergh Joshua M T | 2010 | Journal of Personality and Social Psychology2010，98，3： | 1 |
| 5 | Condylar remodelling and resorption after Le Fort I and bimaxillary osteotomies in patients with anterior open bite显示文摘 | Theo J.M. Hoppenreijs Hans Peter M. Freihofer Paul J.W. Stoelinga Dirk Bram Tuinzing Martin A. van’t Hof | 1998 | International Journal of Oral & Maxillofacial Surgery1998，，： | 1 |
| 6 | In vitro IgE inhibition in B cells by anti-CD23 monoclonal antibodies is functionally dependent on the immunoglobulin Fc domain显示文摘 | Nakamura T Kloetzer WS Brams P | 2000 | Int J Immunopharmacol2000，22，2： | 1 |
| 7 | Testing of nanostructured gas separation membranes in the flue gas of a post-combustion power plant 显示文摘 | BRAM M BRANDS K DEMEUSY T ZHAO L MEULENBERG W A PAULS J GOTTLICHER G PEINEMANN K V SMART S BUCHKREMER H P STOVER D | 2011 | Int J Greenh Gas Control2011，5，1： | 1 |
| 8 | TACI-BLyS signaling via b cell-dendritic cell cooperation is required for cd8 + t cell priming in vivo显示文摘 | MANTCHEV G T BRAM R J | 2006 | Blood2006，107，2： | 1 |
| 9 | Conceptual modelling of behaviour in a virtual environment 显示文摘 | BRAM P OLGA de T | 2007 | Behavior Research Methods2007，4，6： | 1 |
| 10 | Testing of nanostructured gas separation membranes in the flue gas of a post-combustion power plant显示文摘 | Bram M Brands K Demeusy T | 2011 | International Journal of Greenhouse Gas Control2011，5，： | 1 |
| 11 | Comparison of Finite Volume Flux Vector Splittings for the Euler Equations 显示文摘 | W Kyle Anderson James L T Bram V L | 1986 | AIAA Journal1986，24，9： | 1 |
| 12 | Health-related quality-of-life and health-utility reporting in critical care显示文摘Mortality is a well-established patient-important outcome in critical care studies.In contrast,morbidity is less uniformly reported(given the myriad of critical care illnesses and complications of each)but may have a common end-impact on a patient’s functional capacity and health-related quality-of-life(HRQoL).Survival with a poor quality-of-life may not be acceptable depending on individual patient values and preferences.Hence,as mortality decreases within critical care,it becomes increasingly important to measure intensive care unit(ICU)survivor HRQoL.HRQoL measurements with a preference-based scoring algorithm can be converted into health utilities on a scale anchored at 0(representing death)and 1(representing full health).They can be combined with survival to calculate quality-adjusted life-years(QALY),which are one of the most widely used methods of combining morbidity and mortality into a composite outcome.Although QALYs have been use for health-technology assessment decision-making,an emerging and novel role would be to inform clinical decision-making for patients,families and healthcare providers about what expected HRQoL may be during and after ICU care.Critical care randomized control trials(RCTs)have not routinely measured or reported HRQoL(until more recently),likely due to incapacity of some patients to participate in patient-reported outcome measures.Further differences in HRQoL measurement tools can lead to non-comparable values.To this end,we propose the validation of a gold-standard HRQoL tool in critical care,specifically the EQ-5D-5L.Both combined health-utility and mortality(disaggregated)and QALYs(aggregated)can be reported,with disaggregation allowing for determination of which components are the main drivers of the QALY outcome.Increased use of HRQoL,health-utility,and QALYs in critical care RCTs has the potential to:(1)Increase the likelihood of finding important effects if they exist;(2)improve research efficiency;and(3)help inform optimal management of critically ill patients allowing for decision-making about their HRQoL,in additional to traditional health-technology assessments. | Vincent Issac Lau Jeffrey A Johnson Sean M Bagshaw Oleksa G Rewa John Basmaji Kimberley A Lewis M Elizabeth Wilcox Kali Barrett Francois Lamontagne Francois Lauzier Niall D Ferguson Simon J W Oczkowski Kirsten M Fiest Daniel J Niven Henry T Stelfox Waleed Alhazzani Margaret Herridge Robert Fowler Deborah J Cook Bram Rochwerg Feng Xie | 2022 | World Journal of Critical Care Medicine2022，11，4： | 0 |
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