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您的检索式：作者名="Barbara Polese"
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| 1 | Diet and functional dyspepsia: Clinical correlates and therapeutic perspectives显示文摘Hypervigilance and symptoms anticipation,visceral hypersensitivity and gastroduodenal sensorimotor abnormalities account for the varied clinical presentation of functional dyspepsia(FD)patients.Many patients recognize meals as the main triggering factor;thus,dietary manipulations often represent the first-line management strategy in this cohort of patients.Nonetheless,scarce quality evidence has been produced regarding the relationship between specific foods and/or macronutrients and the onset of FD symptoms,resulting in nonstandardized nutritional approaches.Most dietary advises are indeed empirical and often lead to exclusion diets,reinforcing in patients the perception of“being intolerant”to food and self-perpetuating some of the very mechanisms underlying dyspepsia physiopathology(i.e.,hypervigilance and symptom anticipation).Clinicians are often uncertain regarding the contribution of specific foods to dyspepsia physiopathology and dedicated professionals(i.e.,dietitians)are only available in tertiary referral settings.This in turn,can result in nutritionally unbalanced diets and could even encourage restrictive eating behaviors in severe dyspepsia.In this review,we aim at evaluating the relationship between dietary habits,macronutrients and specific foods in determining FD symptoms.We will provide an overview of the evidence-based nutritional approach that should be pursued in these patients,providing clinicians with a valuable tool in standardizing nutritional advises and discouraging patients from engaging into indiscriminate food exclusions. | Marcella Pesce Martina Cargiolli Sara Cassarano Barbara Polese Barbara De Conno Laura Aurino Nicola Mancino Giovanni Sarnelli | 2020 | World Journal of Gastroenterology2020，26，5： | 14 |
| 2 | Good adherence to mediterranean diet can prevent gastrointestinal symptoms:A survey from Southern Italy显示文摘AIM To evaluate how different levels of adherence to a mediterranean diet(MD) correlate with the onset of functional gastrointestinal disorders.METHODS As many as 1134 subjects(598 M and 536 F;age range 17-83 years) were prospectively investigated in relation to their dietary habits and the presence of functional gastrointestinal symptoms.Patients with relevant chronic organic disease were excluded from the study.The Mediterranean Diet Quality index for children and adolescents(KIDMED) and the Short Mediterranean Diet Questionnaire were administered.All subjects were grouped into five categories according to their ages:14-24 years;25-34;35-49;50-64;above 64.RESULTS On the basis of the Rome Ⅲ criteria,our population consisted of 719(63.4%) individuals who did not meet the criteria for any functional disorder and were classified as controls(CNT),172(13.3%) patients meetingcriteria for prevalent irritable bowel syndrome(IBS),and 243(23.3%) meeting criteria for prevalent functional dyspepsia(FD).A significantly lower adherence score in IBS(0.57 ± 0.23,P < 0.001) and FD(0.56 ± 0.24,P < 0.05) was found compared to CNT(0.62 ± 0.21).Females with FD and IBS exhibited significantly lower adherence scores(respectively 0.58 ± 0.24,P < 0.05 and 0.56 ± 0.22,P < 0.05) whereas males were significantly lower only for FD(0.53 ± 0.25,P < 0.05).Age cluster analyses showed a significantly lower score in the 17-24 years and 25-34 year categories for FD(17-24 years:0.44 ± 0.21,P < 0.001;25-34 years:0.48 ± 0.22,P < 0.05) and IBS(17-24 years:0.45 ± 0.20,P < 0.05;24-34 years:0.44 ± 0.21,P < 0.001) compared to CNT(17-24 years:0.56 ± 0.21;25-34 years:0.69 ± 0.20).CONCLUSION Low adherence to MD may trigger functional gastrointestinal symptoms,mainly in younger subjects.Moreover,with increasing age,patients tend to adopt dietary regimens closer to MD. | Francesco Paolo Zito Barbara Polese Letizia Vozzella Antonietta Gala Daniela Genovese Viviana Verlezza Fabiana Medugno Antonello Santini Luigi Barrea Martina Cargiolli Paolo Andreozzi Giovanni Sarnelli Rosario Cuomo | 2016 | World Journal of Gastrointestinal Pharmacology and Therapeutics2016，7，4： | 1 |
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