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| 1 | Micro RNAs as lung cancer biomarkers显示文摘Lung cancer is the leading cause of cancer mortality worldwide. Its high mortality is due to the poor prognosis of the disease caused by a late disease presentation, tumor heterogeneities within histological subtypes, and the relatively limited understanding of tumor biology. Importantly, lung cancer histological subgroups respond differently to some chemotherapeutic substances and side effects of some therapies appear to vary between subgroups. Biomarkers able to stratify for the subtype of lung cancer, prognosticate the course of disease, or predict the response to treatment are in high demand. In the last decade, microR NAs(miR NAs), measured in resected tumor samples or in fine needle aspirate samples have emerged as biomarkers for tumor diagnosis, prognosis and prediction of response to treatment, due to the ease of their detection and in their extreme specificity. Moreover, miR NAs present in sputum, in plasma, in serum or in whole blood have increasingly been explored in the last five years as less invasive biomarkers for the early detection of cancers. In this review we cover the increasing amounts of datathat have accumulated in the last ten years on the use of miR NAs as lung cancer biomarkers. | Valerio Del Vescovo Margherita Grasso Mattia Barbareschi Michela A Denti | 2014 | World Journal of Clinical Oncology2014，5，4： | 11 |
| 2 | p21 RNA and protein expression in non-small cell lung carcinomas:evidence of p53 indepent expression and association with tumoral differentiation显示文摘 | Marchetti A Doglioni C Barbareschi M | 1996 | Oncogene1996，12，6： | 1 |
| 3 | p 21^WAF1 immunohistochemical expression in breast carcinoma: correlations with clinicopathological data, oestrogen receptor status, MIBI expression, p53 gene and protein alterations and relapse-free survival 显示文摘 | Barbareschi M Carlo O Doglioni C | 1996 | Br J Cancer1996，74，2： | 1 |
| 4 | CDX-2 homeobox gene expression is a reliable marker of colorectal adenocarcinoma metastases to the lungs显示文摘 | Barbareschi M Murer B Colby TV | 2003 | Am J Surg Pathol2003，27，： | 1 |
| 5 | CDX 22 homeobox gene product exp ression in neuroendocrine tumors: its role as a marker of intestinal neuroendoerine tumors显示文摘 | Barbareschi M Roldo C Zamboni G | 2004 | Am J Surg Pathol2004，28，9： | 1 |
| 6 | P27Kip1 expression in breast carcinomas: an immunohistochemical study on 512 patients with long-term follow-up显示文摘 | Barbareschi M Van Tinteren H Mauri FA | 2000 | Int J Cancer2000，89，： | 1 |
| 7 | UbcH10 is overexpressed in malignat breast carcinomas显示文摘 | Berlingieri M T Pallante P Sboner A Barbareschi M Bianco M Ferraro A | 2007 | Eur J Cancer2007，43，： | 1 |
| 8 | p21 RNA and protein expression in non-small cell lung carcinomas: evidence of p53-independent expression and association with tumoral differenti- ation显示文摘 | Marchetti A Doglioni C Barbareschi M | 1996 | Oncogene1996，12，6： | 1 |
| 9 | Different prognos tic roles of mutations in the helical and kinase domains of the PIK3CA gene in breast carcinomas显示文摘 | Barbareschi M Buttitta F Felicioni L | 2007 | Clin Cancer Res2007，13，20： | 1 |
| 10 | Prognostic value of intratumoral microvessel density, a measure of tumor angio- genesis,in node - negative breast carcinoma - - results of a muhiparametric study 显示文摘 | Bevilacqua P Barbareschi M Verderio P | 1995 | Breast Cancer Res Treat1995，36，2： | 1 |
| 11 | Cutaneous granulomatous reaction to injectable hyaluronic acid gel 显示文摘 | GHISIANZONI M BIANCHI F BARBARESCHI M | 2006 | Br J Dermatol2006，154，4： | 1 |
| 12 | Different prognosticroles of mutations in the helical and kinase domains of the PIK3CA gene in breast carcinomas 显示文摘 | Barbareschi M Buttitta F Felicioni L | 2007 | Clin Cancer Res2007，13，20： | 1 |
| 13 | Prognostic value of intratumoral microvessel density,a measure of tumor angiogenesis in node-negative breast carcinoma,results of a multiparametric study 显示文摘 | Bevilacqua P Barbareschi M Verderio P | 1995 | Breast Cancer Res Treat1995，36，2： | 1 |
| 14 | Cyclin D1 and retinoblastoma susceptibility gene alterations in non-small cell lung cancer显示文摘 | Marchetti A Doglioni C Barbareschi M | 1998 | Int J Cancer1998，75，2： | 1 |
| 15 | Prognostic value of thymidine phosphorylase expression in breast carcinoma 显示文摘 | Yang QF Barbareschi M Mori I | 2002 | Int J Cancer2002，97，4： | 1 |
| 16 | p63, a p53 homologue, is a selective nuclearmarker of myoepithelial cells of the human breast 显示文摘 | Barbareschi M Pecciarini L Cangi M G | 2001 | Am J Surg Pathol2001，25，： | 1 |
| 17 | CDX-2 homeobox gene expression is a reliable marker of colorectal adenocarcinoma metastases to the lungs显示文摘 | Barbareschi M Murer B Colby TV | 2003 | Am J Surg Pathol2003，27，2： | 1 |
| 18 | Cell membrane reactivity of MIB-1 antibody to Ki67 in human tumors; fact or artifact?显示文摘 | Leonardo E Volante M Barbareschi M | 2007 | Appl Immunohistochem Mol Morphol2007，13，2： | 1 |
| 19 | HER2 status in gastroesophageal cancer: a tissue microarray study of 1040 cases显示文摘 | Rocco Cappellesso Matteo Fassan Esther Hanspeter Jan Bornschein Emanuele S.G. d’Amore Lucia V. Cuorvo Guido Mazzoleni Mattia Barbareschi Marco Pizzi Vincenza Guzzardo Peter Malfertheiner Marjan Micev Maria Guido Luciano Giacomelli Vladislav V. Tsukanov Vi | 2015 | Human Pathology2015，，5： | 1 |
| 20 | Bcl-2 and p53 expression in node-negative breast carcinoma: a study with long-term follow-up 显示文摘 | Barbareschi M Veronese S Caffo O | 1996 | HumPathol1996，27，11： | 1 |
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