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| 1 | The Isogene 1-Deoxy-D-Xylulose 5-Phosphate Synthase 2 Controls Isoprenoid Profiles, Precursor Pathway Allocation, and Density of Tomato Trichomes显示文摘植物 isoprenoids 从先锋被形成由 mevalonate (MVA ) 综合了在 cytosol 或由 methyl-D-erythritol 4 磷酸盐(MEP ) 的小径在质体的小径。尽管先锋的一些交换发生, cytosolic sesquiterpenes 被假定主要源于 MVA,当 plastidial monoterpenes 从 MEP 先锋优先地被生产时。另外的复杂性在 MEP 小径的第一步产生,它被二分叉的 1-deoxy-D-xylulose 5 磷酸盐 synthase isoforms 典型地催化(DXS1, DXS2 ) 。在西红柿(茄属 lycopersicum ) , SlDXS1 基因无所不在地在而 SlDXS2 抄本充满仅仅很少纸巾,成熟的水果期间与高水平被表示,包括年轻叶子,花瓣,和孤立的毛状体。SlDXS2 表示的特定的下面规定被 RNA 干扰在转基因的植物执行调查反馈机制。SlDXS2 下面规定在在二 sesquiterpenes 的 monoterpene -phellandrene 和毛状体的增加导致了减少。而且,进剩余 monoterpenes 并且进 sesquiterpenes 的导出 MVA 的先锋的加入是由 13C 的比较决定了到 12C 天赋同位素比率被提高。SlDXS1 的一条补偿起来规定没被观察。也展出的下面调整的线增加了毛状体密度并且由喂叶的 Spodoptera littoralis 毛虫显示出更少的损坏。结果在 isoprenoid 先锋分配在 modulating isoprenoid 新陈代谢和显著粘性揭示 DXS2 的新奇、非冗余的角色。 | Heike Paetzold Stefan Garms Stefan Bartram Jenny Wieczorek Eva-Maria Uros-Gracia Manuel Rodriguez-Concepcion Wilhelm Boland Dieter Strack Bettina Hause Michael H. Walter | 2010 | Molecular Plant2010，3，5： | 11 |
| 2 | Mutifactorial analysis of risk factors for reduced bone mineral density in patients with Crohn’s disease显示文摘AIM: To determine the prevalence of osteoporosis in a cohort of patients with Crohn’s disease (CD) and to identify the relative significance of risk factors for osteoporosis. METHODS: Two hundred and fifty-eight unselected patients (92 M, 166 F) with CD were studied. Bone mineral density (BMD) was measured at the lumbar spine and hip by dual X-ray absorptiometry. Bone formation was assessed by measuring bone specific alkaline phosphatase (BSAP) and bone resorption by measuring urinary excretion of deoxypyridinoline (DPD) and N-telopeptide (NTX). RESULTS: Between 11.6%-13.6% patients were osteoporotic (T score < -2.5) at the lumbar spine and/or hip. NTX levels were significantly higher in the patients with osteoporosis (P < 0.05) but BSAP and DPD levels were not significantly different. Independent risk factors for osteoporosis at either the lumbar spine or hip were a low body mass index (P < 0.001), increasing corticosteroid use (P < 0.005), and male sex (P < 0.01). These factors combined accounted for 23% and 37% of the reduction in BMD at the lumbar spine and hip respectively. CONCLUSION: Our results confirm that osteoporosis is common in patients with CD and suggest that increased bone resorption is the mechanism responsible for thebone loss. However, less than half of the reduction in BMD can be attributed to risk factors such as corticosteroid use and low BMI and therefore remains unexplained. | Sarah A Bartram Robert T Peaston David J Rawlings David Walshaw Roger M Francis Nick P Thompson | 2006 | World Journal of Gastroenterology2006，12，35： | 2 |
| 3 | Local radiological staging of rectal cancer显示文摘 | Goh V Halligan S Bartram CI | | 0，，： | 1 |
| 4 | Mast cells dis- rupt epithelial barrier function during enteric nematode infection 显示文摘 | McDermott J R Bartram R E Knight P A | 2003 | PNAS2003，100，： | 1 |
| 5 | InternationalEvidence on Financial Derivatives Usage显示文摘 | Bartram S M G W Brown and F Fehle | 2009 | Financial Management Vol 38 No 12009，，： | 1 |
| 6 | Dynamic imaging of posterior compartment pelvic floor dysfunction by evacuation proctography: techniques, indications, results and limitations 显示文摘 | Maglinte DD Bartram C | 2007 | Eur J Radiol2007，61，3： | 1 |
| 7 | Eating in side lying facilitates rehabilitation in neurogenic dysphagia显示文摘 | O'Donoghue S Bartram C | 1997 | Brain Inj1997，11，： | 1 |
| 8 | Anal endosonography in the evaluation of perianal sepsis and fistula in ano显示文摘 | Law PJ Talbot RW Bartram CI | 1989 | Br J Surg1989，76，： | 1 |
| 9 | Clinical examination, endosonography, and MR imaging in preoperative assessment of fistula in ano: comparison with outcome-based reference standard显示文摘 | Buchanan G N Halligan S Bartram C I | 2004 | Radiology2004，233，3： | 1 |
| 10 | The role of CT colonography in colorectal cancer screening显示文摘 | Nicholson FB Bano JL Bartram CI | 2005 | Am J Gastroenterol2005，100，4： | 1 |
| 11 | The role of transforming growth faetorl3 in lung development and disease 显示文摘 | Bartram U Speer CP | 2004 | Chest2004，125，2： | 1 |
| 12 | Acute lympho- blastic leukemia in children: treatment planning via minimal residual disease assessment 显示文摘 | Bartram CR Schrauder A Kohler R | 2012 | Dtsch Arztebl Int2012，109，40： | 1 |
| 13 | The role of transforming growth factor beta in lung development and disease显示文摘 | Bartram U Speer C P | 2004 | Chest2004，125，2： | 1 |
| 14 | Ion-Size Effects in Color Centers显示文摘 | Bartram R H Stoneham A M Gash P | 1968 | Jphys Rev1968，176，315： | 1 |
| 15 | Translocation of c- abl oncogene correlates with the presence of a Philadelphia chro- mosome in chronic myelocytic leukaemia 显示文摘 | Bartram CR de Klein A Hagemeijer A | 1983 | Nature1983，306，5940： | 1 |
| 16 | Quantitative tumor perfusion assessment with multidetector CT: are measurements from two commercial software packages interchangeable? 显示文摘 | Goh V Halligan S Bartram C I | 2007 | Radiology2007，242，3： | 1 |
| 17 | The role of transforming growth factor beta in lung development and disease 显示文摘 | Bartram U Speer CP | 2004 | Chest2004，125，2： | 1 |
| 18 | Infants in a neonatal inten- sive care unit:parental response显示文摘 | Carter JD Mulder RT Bartram AF | 2005 | Arch Dis Child Fetal Neonatal Ed2005，90，2： | 1 |
| 19 | Global Access to Safe Water: Accounting for Water Quality and the Resulting Impact on MDG Progress显示文摘 | Onda K LoBuglio J Bartram J | 2012 | Int J Environ Res Pub Heal2012，9，3： | 1 |
| 20 | Leading prognostic relevance of the BCR-ABL translocation in adult acute B-lineage lymphoblastic leukemia:a prospective study of the German Multicenter Trial Group and confirmed polymerase chain reaction anlysis显示文摘 | Gleissner B Gokbuget N Bartram CR | 2002 | Blood2002，99，： | 1 |
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