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| 1 | Current medical treatment of estrogen receptor-positive breast cancer显示文摘Approximately 80% of breast cancers(BC) are estrogen receptor(ER)-positive and thus endocrine therapy(ET) should be considered complementary to surgery in the majority of patients. The advantages of oophorectomy, adrenalectomy and hypophysectomy in women with advanced BC have been demonstrated many years ago, and currently ET consist of(1) ovarian function suppression(OFS), usually obtained using gonadotropinreleasing hormone agonists(Gn RHa);(2) selective estrogen receptor modulators or down-regulators(SERMs or SERDs); and(3) aromatase inhibitors(AIs), or a combination of two or more drugs. For patients aged less than 50 years and ER+ BC, there is no conclusive evidence that the combination of OFS and SERMs(i.e., tamoxifen) or chemotherapy is superior to OFS alone. Tamoxifen users exhibit a reduced risk of BC, both invasive and in situ, especially during the first 5 years of therapy, and extending the treatment to 10 years further reduced the risk of recurrences. SERDs(i.e., fulvestrant) are especially useful in the neoadjuvant treatment of advanced BC, alone or in combination with either cytotoxic agents or AIs. There are two types of AIs: type Ⅰ are permanent steroidal inhibitors of aromatase, while type Ⅱ are reversible nonsteroidal inhibitors. Several studies demonstrated the superiority of the third-generation AIs(i.e., anastrozole and letrozole) compared with tamoxifen, and adjuvant therapy with AIs reduces the recurrence risk especially in patients with advanced BC. Unfortunately, some cancers are or became ET-resistant, and thus other drugs have been suggested in combination with SERMs or AIs, including cyclin-dependent kinase 4/6 inhibitors(palbociclib) and mammalian target of rapamycin(m TOR) inhibitors, such as everolimus. Further studies are required to confirm their real usefulness. | Franco Lumachi Davide A Santeufemia Stefano MM Basso | 2015 | World Journal of Biological Chemistry2015，6，3： | 16 |
| 2 | 国际胃袖状切除专家共识:基于>12000手术病例的最佳操作指南显示文摘腹腔镜胃袖状切除术(1aparoscopic sleeve gastrectomy,LSG)系相对较新的减重手术方式。因其操作相对简单、治疗肥胖合并疾病及减重效果明显,逐步得以广泛接受。目前美国代谢与减重手术协会将其推荐为肥胖症治疗的单独标准术式。2011年3月25~26日, | 苏远涛 徐安安 朱江帆 Diaz AA Arvidsson D Baker RS Basso N Bellanger D Boza C El Mourad H France M Gagner M Galvao-Neto M Higa KD Himpens J Hutchinson CM Jacobs M Jorgensen JO Jossart G Lakdawala M Nguyen NT Nocca D Prager G Pomp A Ramos AC Rosenthal RJ Shah S Vix M Wittgrove A Zundel N | 2013 | 中国微创外科杂志2013，13，9： | 12 |
| 3 | Cloning and expression of functional shikimate dehydrogenase from Mycobacterium tuberculosis H37Rv显示文摘 | Magalhaes M L B Pereira C P Basso L A | 2002 | Protein Expression and Purification2002，26，： | 2 |
| 4 | A phase Ⅱ, randomized, non-comparative clinical trial of the effect of bevaeizumab (BV) alone or in combination with irinotecan (CPT) on 6-month progression free survival ( PFS6 ) in recurrent, treatment-refractory glioblastoma (GBM)显示文摘 | Brandes AA Tosoni A Basso U | 2008 | J Clin Oncol2008，26，20： | 1 |
| 5 | Effect of chemical interesterification on physicochemical properties and industrial applications of c anola oil and fully hydrogenated cottonseed oil blends 显示文摘 | RIBEIRO A P B BASSO R C GRIMALDI R | 2009 | Journal of Food Lipids2009，16，3： | 1 |
| 6 | Reversal of axonal loss and disa bility in a mouse model of progressive multiple sclerosis 显示文摘 | Basso A S Frenkel D Quintana FJ Costa-Pinto F A Petrovic Stojkovic S Puckett L | 2008 | J Clin Invest2008，118，： | 1 |
| 7 | Analytical Control of Photocatalytic Treatments: Degradation of a Sulfonated Azo Dye 显示文摘 | Prevot A B Basso A Baiocchi C | 2004 | Anal Bioanal Chem2004，378，1： | 1 |
| 8 | Survival study of metallo- thionein-1 transgenic mice and respective controls(C57BL/6J) :in- fluence of a zinc - enriched environment 显示文摘 | Malavolta M Basso A Piaeenza F | 2012 | Rejuvenation Re- search2012，15，2： | 1 |
| 9 | Assessing potential of biochar for increasing water-holding capacity of sandy soils显示文摘 | Basso A S Miguez F E Laird D A | 2013 | Global Change Biology Bioenergy2013，5，2： | 1 |
| 10 | 12-lead ECG in the athlete: physiological versus pathological abnormalities显示文摘 | Corrado D Biffi A Basso C | 2009 | Br J Sports Med2009，43，9： | 1 |
| 11 | Determination of extracellular and intracellular pH of Bacillus subtilis suspension under CO2 treatment 显示文摘 | Spilimbergo S Bertucco A Basso G | 2005 | Biotechnology and Bioengineering2005，92，： | 1 |
| 12 | Mutations in desmoglein-2 gene are associated with arrhythmogenic right ventricular cardiomyopathy显示文摘 | Pilichou K Nava A Basso C | 2006 | Circulation2006，113，9： | 1 |
| 13 | Flexible-elastic eo- polymerized polyurethane-tannin foams显示文摘 | Basso M C Giovando S Pizzi A | 2014 | Journal of Ap- plied Polymer Science2014，131，40： | 1 |
| 14 | Cadmium uptake by lignocellulosic materia s: effect oflignin content显示文摘 | Basso M C Cerrella E G Cukiemlan A L | 2004 | Sep Sci Techn2004，39，： | 1 |
| 15 | Antiparasitic activity of substituted carbanilide complexes显示文摘 | CUCKLER A C MALANGA C M BASSO A J | 1955 | Science1955，122，3162： | 1 |
| 16 | Transport of MPEG-4 over IP/RTP显示文摘 | Basso A Varakliotis S | 2000 | IEEE International Conference2000，，2： | 1 |
| 17 | Long-term results of hiatal hernia mesh repair and antireflux laparoscopic surgery 显示文摘 | Soricelli E Basso N Genco A | 2009 | Surg Endosc2009，23，11： | 1 |
| 18 | A data envelopment analysis approach to measure the mutual fund performance显示文摘 | Basso A Funari S | 2001 | European Journal of Operational Research2001，135，3： | 1 |
| 19 | Clinical profile and long-term follow-up of 37 families with arrhythmogenic right ventricular cardiomyopathy显示文摘 | Nava A Bauce B Basso C | 2000 | J Am Coll Cardiol2000，36，3： | 1 |
| 20 | Interactions of cyclophilin with the mitochondrial inner membrane and regulation of the permeability transition pore,and cyclosporin Asensitive channel显示文摘 | Nicolli A Basso E Petronilli V | 1996 | J Biol Chem1996，271，4： | 1 |
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