|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Neuroprotective effect of systemic and/or intravitreal rosuvastatin administration in rat glaucoma model显示文摘AIM:To evaluate the neuroprotective effect of rosuvastatin,in a rat experimental glaucoma model.· METHODS:Ocular hypertension was induced in right eyes of Long-Evans rats(n=30) by cauterization of three episcleral veins.Left eyes were defined as controls.Rats were divided into five groups:oral rosuvastatin,intravitreal rosuvastatin,oral +intravitreal rosuvastatin,intravitreal sham and glaucoma without intervention.Rats were sacrificed at day 14.Retinal ganglion cell(RGC) number was assessed by histopathological analysis.Terminal deoxynucleotidyl transferase-mediated dUTP-nick end-labeling(TUNEL) staining and the expression of glial fibrillary acidic protein(GFAP) in RGC layer was also examined.· RESULTS:A significant intraocular pressure(IOP)elevation was seen(P=0.002).Elevated IOP resulted in a significant decrease in number of RGCs in group 5(70.33±8.2 cells/mm^2) when compared with controls(92.50±13.72 cells/mm^2;P=0.03).The RGC number in group 1(92.4±7.3 cells/mm^2) was significantly higher than group 5(P=0.03).The numbers of RGC in groups 2,3(57.3±8.2 cells/mm^2,60.5±12.9 cells/mm^2) were comparable with that of group 5(P=0.18 and P=0.31).The apoptosis rates with TUNEL staining were also parallel to RGC number.Animals with experimentally induced glaucoma showed an increase in retinal GFAP immunoreactivity.· CONCLUSION:Decrease in RGC loss and apoptosis suggest the neuroprotective potential of oral rosuvastatin treatment in a rat model of ocular hypertension.However intravitreal rosuvastatin showed a contrary effect and further studies are required. | Metin Unlu Zeynep Aktas Pinar Uyar Gocun Sevil Ozger Ilhan Murat Hasanreisoglu Berati Hasanreisoglu | 2016 | International Journal of Ophthalmology(English edition)2016，9，3： | 7 |
| 2 | Trabeculectomy with large area mitomycin-C application as a first-line treatment in advanced glaucoma: retrospective review显示文摘AIM: To evaluate the outcomes of trabeculectomy with large area mitomycin-C(MMC) application as a first line treatment in advanced glaucoma. ·METHODS: The records of 55 patients with severe visual field defects undergoing trabeculectomy were retrospectively reviewed. The patients were classified as first-line therapy to either early trabeculectomy(initial trabeculectomy-Group 1) or long term medical therapy followed by trabeculectomy(primary trabeculectomy-Group 2). Trabeculectomy was performed with large-area MMC application. Intraocular pressure(IOP) values,visual acuities,mean deviations,morphology and function of the blebs,necessity for anti-glaucomatous medications and surgical complications were reported. ·RESULTS: There were 20 eyes of 18 patients in Group 1 and 37 eyes of 37 patients in Group 2. The mean preoperative IOPs in Groups 1 and 2 were 40.2±10.0mmHg(27-68mmHg) and 29.0±4.4mmHg(21-41mmHg),respectively(P=0.001). Average preoperative mean deviations(MD) in Groups 1 and 2 were 17.4±2.8dB(13.3-23dB) and 17.9± 2.4dB(13.7-23.2dB),respectively(P=0.441). Postoperative IOPs significantly decreased and were comparable in both Groups. The mean number of medications was significantly higher in Group 2(P =0.005). No cystic bleb formation was observed in Group 1,whereas 4 patients from Group 2(10.8%) developed cystic bleb(P =0.040). No visually devastating complication has occurred in both Groups. ·CONCLUSION: Initial trabeculectomy with large areaMMC application might be applied in patients with advanced glaucoma with low complication rates. Long-term topically applied anti-glaucomatous medications seem to increase the risk of cystic bleb formation. | Zeynep Aktas Safak Korkmaz Murat Hasanreisoglu Merih Onol Berati Hasanreisoglu | 2014 | International Journal of Ophthalmology(English edition)2014，7，1： | 6 |
| 3 | Retinal vessel diameters and their correlation with retinal nerve fiber layer thickness in patients with pseudoexfoliation syndrome显示文摘AIM: To compare retinal artery-vein diameters(RAVDs)of patients with pseudoexfoliation(PSX) syndrome with healthy controls and investigate the correlations between retinal nerve fiber layer(RNFL) thickness parameters and RAVDs.METHODS: Seventeen eyes with PSX and 17 eyes of age-matched controls were included in the study. All participants underwent routine ophthalmological examination, Humphrey visual field and RNFL examination by using Stratus OCT. Retinal images were obtained by using a retinal camera(Topcon 501X).RAVDs were measured from inferior nasal, inferior temporal, superior nasal and superior temporal arcuates by using IMAGEnet software. Superior, inferior, nasal,temporal and average RNFL thicknesses were recorded.RAVDs and RNFL parameters in groups and correlations were analyzed by Mann-Whitney U and Spearmann correlation tests.RESULTS: Only inferior quadrant and average RNFL thickness were detected thinner in the PSX group compared with control group(P =0.009, P =0.038,respectively). No statistically significant difference regarding RAVDs was found between two groups.CONCLUSION: RAVDs seems to be comparable in the PSX and control group. RNFL is thinner in the inferior quadrant in the PSX group. RNFL thickness and RAVDs show significant correlations in both groups. This correlation doesn't seem to be specific to PSX. | Mehmet Cuneyt Ozmen Zeynep Aktas Burcin Kepez Yildiz Murat Hasanreisoglu Berati Hasanreisoglu | 2015 | International Journal of Ophthalmology(English edition)2015，8，2： | 3 |
| 4 | Factors affecting smoking in schizophrenia显示文摘 | Beratis S Katrivanou A Gourzis P | 2001 | Compr Psychiatry2001，42，5： | 1 |
| 5 | Effect of prenatal tobaccosmoke exposure on fetal growth potential显示文摘 | Varvarigou AA Fouzas S Beratis NG | 2010 | J Perinat Med2010，38，6： | 1 |
| 6 | Kniest syndrome with dominant inheritance and mucopolysacchariduria显示文摘 | Kim HJ Beratis NG Brill P | 1975 | Am J Hum Genet1975，27，6： | 1 |
| 7 | Effect of bevacizumab on comealneovascul in experimental rabbit model显示文摘 | Ahmed A Berati H Nalan A | | 0，，7： | 1 |
| 8 | Symptomatology of the initial prodromal phase in schizophrenia显示文摘 | Gourzis P Katrivanou A Beratis S | 2002 | Schizophr Bull2002，28，4： | 1 |
| 9 | Psychosocial issues and quality of life in patients on renal replacement therapy显示文摘 | Panagopoulou A Hardalias A Berati S | | 0，，02： | 1 |
| 10 | Psychosocial issues and quality of life in patients on renal replacement therapy 显示文摘 | Panagopoulou A Hardalias A Berati S | 2009 | Sa- udi J Kidney Dis Transpl2009，20，2： | 1 |
| 11 | Psychosocial issues and quality of life in patients on renal replacement therapy显示文摘 | Panagopoulou A Hardalias A Berati S | 2009 | Saudi J Kidney Dis Transpl2009，20，2： | 1 |
| 12 | Increased activity of lysosomal acid hydrolases in the cell- free cerebrospinal fluid of bacterial meningitis显示文摘 | Beratis NG Mavrommatis T Hatiris I | 1997 | Pediatr Res1997，，： | 1 |
| 13 | Matrix metalloproteinase-9 expression in retinal ganglion cell layer and effect of topically applied brimonidine tartrate 0.2% therapy on this expression in an endothelin-1-induced optic nerve ischemia model显示文摘 | Zeynep Aktas Gokhan Gurelik P?nar Uyar G??ün Nalan Akyürek Merih ?nol Berati Hasanreiso?lu | 2010 | International Ophthalmology2010，，3： | 1 |
| 14 | Psychosocial issues and quality of life in patients on renal replacement therapy 显示文摘 | Panagopoulou A Hardalias A Berati S | 2009 | Saudi J Kidney Dis Transplant2009，20，： | 1 |
| 15 | Psy- chosocial issues and quality of life in patients on renal replace- ment therapy显示文摘 | Panagopoulou A Hardalias A Berati S Fourtounas C | 2009 | Saudi J Kidney Dis Transpl2009，20，2： | 1 |
| 16 | Antimicrobial use and colonization with erythromycin-resistant streptococcus pneumoniae in Greece during the first 2 yeais of life显示文摘 | Syrogiannopulos GA Grivea N Davies TA Katopodis GD Appelbaum PC Beratis NG | 2000 | Clin Infect Dis2000，31，4： | 1 |
| 17 | Effect of bevacizumab on corneal neovascularization in experimental rabbit model显示文摘 | Ahmed A Berati H Nalan A | | 0，，07： | 1 |
| 18 | Psychosocial status in pre-adolescent children with beta-thalassemia 显示文摘 | Beratis S | 1993 | J Psychosomat Res1993，37，3： | 1 |
| 19 | Factors affecting smoking in schizophrenia显示文摘 | Beratis S Katrivanou A Gourzis P | 2001 | Compr Psychiatry2001，42，： | 1 |
| 20 | Resistance patterns of streptococcus pneumoniae from carriers attending day-care centers in southwestern Greece 显示文摘 | Syrogiarmopoulos GA Grivea IN Beratis NG | 1997 | Clin Infect Dis1997，25，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员