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| 1 | Computed tomography-guided percutaneous core needle biopsy in pancreatic tumor diagnosis显示文摘AIM: To evaluate the techniques, results, and complications related to computed tomography(CT)-guided percutaneous core needle biopsies of solid pancreatic lesions.METHODS: CT-guided percutaneous biopsies of solid pancreatic lesions performed at a cancer reference center between January 2012 and September 2013 were retrospectively analyzed. Biopsy material was collected with a 16-20 G Tru-Core needle(10-15 cm; Angiotech, Vancouver, CA) using a coaxial system and automatic biopsy gun. When direct access to the lesion was not possible, indirect(transgastric or transhepatic) access or hydrodissection and/or pneumodissection maneuvers were used. Characteristics of the patients, lesions, procedures, and histologic results were recorded using a standardized form. RESULTS: A total of 103 procedures included in the study were performed on patients with a mean age of 64.8 year(range: 39-94 year). The mean size of the pancreatic lesions was 45.5 mm(range: 15-195 mm). Most(75/103, 72.8%) procedures were performed via direct access, though hydrodissection and/or pneumodissection were used in 22.2%(23/103) of cases and indirect transhepatic or transgastric access was used in 4.8%(5/103) of cases. Histologic analysis was performed on all biopsies, and diagnoses were conclusive in 98.1%(101/103) of cases, confirming3.9%(4/103) of tumors were benign and 94.2%(97/103) were malignant; results were atypical in 1.9%(2/103) of cases, requiring a repeat biopsy to diagnose a neuroendocrine tumor, and surgical resection to confirm a primary adenocarcinoma. Only mild/moderate complications were observed in 9/103 patients(8.7%),and they were more commonly associated with biopsies of lesions located in the head/uncinate process(n =8), than of those located in the body/tail(n = 1) of the pancreas, but this difference was not significant.CONCLUSION: CT-guided biopsy of a pancreatic lesion is a safe procedure with a high success rate, and is an excellent option for minimally invasive diagnosis. | Chiang J Tyng Maria Fernanda A Almeida Paula NV Barbosa Almir GV Bitencourt José Augusto AG Berg Macello S Maciel Felipe JF Coimbra Luiz Henrique O Schiavon Maria Dirlei Begnami Marcos D Guimares Charles E Zurstrassen Rubens Chojniak | 2015 | World Journal of Gastroenterology2015，21，12： | 14 |
| 2 | The effects of insulin,and insulin-like growth factors Ⅰ and Ⅱ on human ovarian follicles in long-term culture显示文摘 | Louhio H Hovatta O Sj(o)berg J | 2000 | Mol Hum Reprod2000，6，8： | 1 |
| 3 | Whole body protein kinetics during hypocaloric and normocaloric feeding in critically ill patients显示文摘 | Berg A Rooyackers O Bellander BM | 2013 | Crit Care2013，17，4： | 1 |
| 4 | Glomerular and tubular renal functions after long-term medication of sulphasalazine,olsalazine,and mesalazine in patients with ulcerative colitis显示文摘 | Berg KJ Fausa O | 2000 | Inflamn Bowel Dis2000，6，4： | 1 |
| 5 | X-stop versus decompressive surgery for lumbar neurogenic intermittent claudication:randomized controlled trial with 2-year follow-up显示文摘 | Str(o)mqvist BH Berg S Gerdhem P | 2013 | Spine2013，38，17： | 1 |
| 6 | Certain special features of the formation of welds made at high speeds显示文摘 | PATON E O MANDEL' BERG S L Sidorenko B G | 1971 | Autom Weld1971，24，8： | 1 |
| 7 | Pharmacologically elevated levels of endogenous kynurenic acid prevent nicotine-induced activation of nigral dopamine neurons显示文摘 | Erhardt S (o)berg H Engberg G | 2001 | Naunyn Schmiedebergs Arch Pharmacol2001，363，1： | 1 |
| 8 | 14-3-3 Proteins in the Nervous System显示文摘 | BERG D VIOLZMANN C RIESS O | 2003 | Nat Rev Neurosci(S1471- 0048)2003，4，： | 1 |
| 9 | Growth and digestibility effects of soya lecithin and choline chloride on juvenile Atlantic salmon显示文摘 | S S O Hung G M Berge T Storebakken | 1997 | Aquaculture Nutrition1997，3，： | 1 |
| 10 | Copper amend- ment of agricultural soil selects for bacterial antibiotic resistance in the field 显示文摘 | BERG J TOM - PETERSON A NYBROE O | 2005 | Letters in Applied Microbiology2005，40，2： | 1 |
| 11 | Pomegranate seed oil, a rich source of punicic acid, prevents diet- induced obesity and insulin resistance in mice 显示文摘 | Vroegrijk I O C M van Diepen J A van den Berg S | 2011 | Food Chem Toxicol2011，49，6： | 1 |
| 12 | Hygroscopic growth of aerosol particles in the marine boundary layer over the Pacific and Southern Oceans during the First Aerosol Characterization Experiment (ACE 1)显示文摘 | Berg O H Swietlicki E Krejci R | 1998 | J Geophy Res1998，103，16： | 1 |
| 13 | Clinical and laboratory measures of postural balance in an elderly population显示文摘 | BERG K O MAKI B E WILLIAMS J I | 1992 | Arch Phys Med Rehabil1992，73，1： | 1 |
| 14 | 14-3-3 proteins in the nervous sys- tem显示文摘 | Berg D Holzmann C Riess O | 2003 | Nat Rev Neurosci2003，4，9： | 1 |
| 15 | Measuring balance in the elderly:validation of an instrument显示文摘 | BERG K O WOOD-DAUPHINEE S L WILLIAMS J I | 1992 | Can Public Health1992，83，2： | 1 |
| 16 | Comparison of the efficacy and safety of faropenem daloxate and cefuroxime axetil for the treatment of acute bacterial maxillary sinusitis in adults显示文摘 | Siegert R Berg O Gehanno P | | 0，，04： | 1 |
| 17 | Clinical diagnosis and management ofamyotrophic lateral scleosis显示文摘 | Hardiman O van den Berg LH Kieman MC | | 0，，11： | 1 |
| 18 | The emergence of koi her- pesvirus and its significance to European aquaculture 显示文摘 | Haenen O Way K Berg'mann S | 2004 | Bull Eur Assoc Fish Pathol2004，24，6： | 1 |
| 19 | 显示文摘 | Van den Berg A W C Aredn C O | 2008 | Chemical Communica- tions2008，6，： | 1 |
| 20 | Genetic and phenotypic diversity of Bacillus polymyxa in soil and in the wheat rhizosphere显示文摘 | MAVINGUI P LAGUERRE G BERGE O | 1992 | Applied and Environmental Microbiology1992，58，6： | 1 |
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